Alopecia areata and the gut—the link opens up for novel therapeutic interventions

Intestinal barriers protect against disease

(2018) Sandra Citi   SCIENCE

649 Gut microbiota plays a role in the development of alopecia areata

(2017) L. Nair et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inflammatory bowel disease is associated with an increased risk of inflammatory skin diseases: A population-based cross-sectional study

(2017) Miri Kim et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Commensal bacteria make GPCR ligands that mimic human signalling molecules

(2017) Louis J. Cohen et al.   NATURE

Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata

(2017) Gabriel Skogberg et al.   PHARMACOLOGY & THERAPEUTICS

Nutritional influences of overfeeding on experimental outcomes in laboratory mice: consequences for gut microbiota and other functional studies

(2016) Stephan C. Bischoff et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

(2016) Mingming Sun et al.   JOURNAL OF GASTROENTEROLOGY

Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration

(2016) Eva Rosenkranz et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

GPR41 and GPR43 in Obesity and Inflammation – Protective or Causative?

(2016) Zhiwei Ang et al.   Frontiers in Immunology

Individualized Responses of Gut Microbiota to Dietary Intervention Modeled in Humanized Mice

(2016) Samuel A. Smits et al.   mSystems

Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

(2015) Aaron Lerner et al.   AUTOIMMUNITY REVIEWS

Modulation of the faecal microbiome of healthy adult dogs by inclusion of potato fibre in the diet

(2015) Matthew R. Panasevich et al.   BRITISH JOURNAL OF NUTRITION

Revisiting the hygiene hypothesis for allergy and asthma

(2015) Andrew H. Liu   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetic basis of autoimmunity

(2015) Alexander Marson et al.   JOURNAL OF CLINICAL INVESTIGATION

Allergy in Children in Hand Versus Machine Dishwashing

(2015) B. Hesselmar et al.   PEDIATRICS

Role of Small Intestinal Bacterial Overgrowth in Functional Gastrointestinal Disorders

(2015) Chang Hwan Choi et al.   Journal of Neurogastroenterology and Motility

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

(2014) Mohamed S. Donia et al.   CELL

The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata

(2014) Taisuke Ito et al.   EXPERIMENTAL DERMATOLOGY

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Epithelial Cell Tight Junctions by Protease-Activated Receptor 2

(2014) Shuhei ENJOJI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Crosstalk at the mucosal border: importance of the gut microenvironment in IBS

(2014) Lena Öhman et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiome of the Hadza hunter-gatherers

(2014) Stephanie L. Schnorr et al.   Nature Communications

Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation

(2014) Chang H. Kim et al.   Immune Network

Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease

(2013) Lotta Nylund et al.   BMC MICROBIOLOGY

Role of “Western Diet” in Inflammatory Autoimmune Diseases

(2013) Arndt Manzel et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Tolerance induction by hair-specific keratins in murine alopecia areata

(2013) Ulrike Erb et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Feed Your Tregs More Fiber

(2013) J. Bollrath et al.   SCIENCE

Intestinal Epithelial Barrier Dysfunction in Disease and Possible Therapeutical Interventions

(2012) R.-M. Catalioto et al.   CURRENT MEDICINAL CHEMISTRY

Genetic Basis of Alopecia Areata

(2012) Ali Jabbari et al.   DERMATOLOGIC CLINICS

A framework for human microbiome research

(2012)   NATURE

Alopecia Areata

(2012) Amos Gilhar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut microbiota, immune development and function

(2012) Stig Bengmark   PHARMACOLOGICAL RESEARCH

Low diversity of the gut microbiota in infants with atopic eczema

(2011) Thomas R. Abrahamsson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

Commensal flora and the regulation of inflammatory and autoimmune responses

(2011) Jan Kranich et al.   SEMINARS IN IMMUNOLOGY

Hair follicle is a target of stress hormone and autoimmune reactions

(2010) Taisuke Ito   JOURNAL OF DERMATOLOGICAL SCIENCE

Collapse of Immune Privilege in Alopecia Areata: Coincidental or Substantial?

(2010) Amos Gilhar   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

(2010) Lynn Petukhova et al.   NATURE

Diet, gut microbiota and immune responses

(2010) Kendle M Maslowski et al.   NATURE IMMUNOLOGY

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small intestinal bacterial overgrowth and intestinal permeability

(2010) Ernesto Cristiano Lauritano et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Small intestinal bacterial overgrowth syndrome

(2010) Jan Bures   WORLD JOURNAL OF GASTROENTEROLOGY

Tight Junctions, Intestinal Permeability, and Autoimmunity

(2009) Jeroen Visser et al.   Annals of the New York Academy of Sciences

Stress and autoimmunity

(2009) Ljudmila Stojanovich   AUTOIMMUNITY REVIEWS

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The genetics of human autoimmune disease

(2009) Pietro Invernizzi et al.   JOURNAL OF AUTOIMMUNITY

Recent insights in the epidemiology of autoimmune diseases: Improved prevalence estimates and understanding of clustering of diseases

(2009) Glinda S. Cooper et al.   JOURNAL OF AUTOIMMUNITY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

The therapeutic helminth?

(2009) Derek M. McKay   TRENDS IN PARASITOLOGY

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY

Protease-activated receptor 2 and gut permeability: a review

(2008) l. bueno et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Stress as a trigger of autoimmune disease

(2007) Ljudmila Stojanovich et al.   AUTOIMMUNITY REVIEWS

Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack

(2007) Taisuke Ito et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY