EJE PRIZE 2018: A gut feeling about glucagon

Evidence of a liver–alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

(2018) Nicolai J. Wewer Albrechtsen et al.   DIABETOLOGIA

Higher Endogenous Glucose Production During OGTT vs Isoglycemic Intravenous Glucose Infusion

(2016) Asger Lund et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia

(2016) A. E. Junker et al.   JOURNAL OF INTERNAL MEDICINE

Involvement of steatosis-induced glucagon resistance in hyperglucagonaemia

(2016) Malte P. Suppli et al.   MEDICAL HYPOTHESES

Risk Factors for and Management of Postpancreatectomy Hepatic Steatosis

(2016) N. Takemura et al.   Scandinavian Journal of Surgery

Evidence of Extrapancreatic Glucagon Secretion in Man

(2015) Asger Lund et al.   DIABETES

Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes

(2015) Nicolai A. Rhee et al.   DIABETOLOGIA

Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis

(2015) M. Gyldenløve et al.   JOURNAL OF INTERNAL MEDICINE

Islet α cells and glucagon—critical regulators of energy homeostasis

(2015) Jonathan E. Campbell et al.   Nature Reviews Endocrinology

Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease

(2015) Darleen A. Sandoval et al.   PHYSIOLOGICAL REVIEWS

Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass

(2015) Mark J. Solloway et al.   Cell Reports

Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes

(2014) Mikkel Christensen et al.   DIABETES

Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients With Maturity-Onset Diabetes of the Young--Type 2 and Type 3

(2014) S. H. Ostoft et al.   DIABETES

Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

(2014) Nicolai J. Wewer Albrechtsen et al.   DIABETOLOGIA

Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

(2014) Jonatan I. Bagger et al.   DIABETOLOGIA

The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

(2014) N A Rhee et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans

(2014) Monika J Bak et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, High-performance Quadrupole and an Ultra-high-field Orbitrap Analyzer

(2014) Richard Alexander Scheltema et al.   MOLECULAR & CELLULAR PROTEOMICS

The incretin effect in Korean subjects with normal glucose tolerance or type 2 diabetes

(2013) Tae Jung Oh et al.   CLINICAL ENDOCRINOLOGY

Secretion of Glucose-Dependent Insulinotropic Polypeptide in Patients With Type 2 Diabetes: Systematic review and meta-analysis of clinical studies

(2013) S. Calanna et al.   DIABETES CARE

Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

(2013) S. Calanna et al.   DIABETOLOGIA

Characterisation of oral and i.v. glucose handling in truncally vagotomised subjects with pyloroplasty

(2013) Astrid Plamboeck et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Blockade of Glucagon-like Peptide 1 Receptor Corrects Postprandial Hypoglycemia After Gastric Bypass

(2013) Marzieh Salehi et al.   GASTROENTEROLOGY

Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

(2013) Mikkel B. Christensen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease

(2013) Thomas Idorn et al.   KIDNEY INTERNATIONAL

Postpartum reversibility of impaired incretin effect in gestational diabetes mellitus

(2013) M. Kosinski et al.   REGULATORY PEPTIDES

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

Roux-en Y Gastric Bypass Surgery Reduces Hedonic Hunger and Improves Dietary Habits in Severely Obese Subjects

(2012) Jennifer Ullrich et al.   OBESITY SURGERY

The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

(2011) Asger Lund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Integrated Physiology/Obesity

(2011)   DIABETES

Glucose-Dependent Insulinotropic Polypeptide: A Bifunctional Glucose-Dependent Regulator of Glucagon and Insulin Secretion in Humans

(2011) M. Christensen et al.   DIABETES

Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity

(2011) F. K. Knop et al.   DIABETES OBESITY & METABOLISM

Impaired Regulation of the Incretin Effect in Patients with Type 2 Diabetes

(2011) Jonatan I. Bagger et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes

(2010) Kristine J. Hare et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduced Glucose Tolerance and Insulin Resistance Induced by Steroid Treatment, Relative Physical Inactivity, and High-Calorie Diet Impairs the Incretin Effect in Healthy Subjects

(2010) K. B. Hansen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass: Unraveling the Role of Gut Hormonal and Pancreatic Endocrine Dysfunction

(2010) Atoosa Rabiee et al.   JOURNAL OF SURGICAL RESEARCH

Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis

(2010) F.K. Knop et al.   REGULATORY PEPTIDES

Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes

(2010) Mikkel Christensen et al.   REGULATORY PEPTIDES

Exogenous Glucose-Dependent Insulinotropic Polypeptide Worsens Post prandial Hyperglycemia in T ype 2 Diabetes

(2009) C. W. Chia et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling?

(2009) F. K. Knop   DIABETOLOGIA

Preserved Inhibitory Potency of GLP-1 on Glucagon Secretion in Type 2 Diabetes Mellitus

(2009) Kristine J. Hare et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM