The synthetic cathinone α-pyrrolidinovalerophenone (α-PVP): pharmacokinetic and pharmacodynamic clinical and forensic aspects

Neurocognitive dysfunction following repeated binge-like self-administration of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)

(2018) Kaveish Sewalia et al.   NEUROPHARMACOLOGY

MDPV and α-PVP use in humans: The twisted sisters

(2018) Laurent Karila et al.   NEUROPHARMACOLOGY

Stability of synthetic cathinones in oral fluid samples

(2017) Briana Miller et al.   FORENSIC SCIENCE INTERNATIONAL

α-Pyrrolidinophenones: a new wave of designer cathinones

(2017) Jolanta B. Zawilska et al.   Forensic Toxicology

Hair Testing for Drugs of Abuse and New Psychoactive Substances in a High-Risk Population

(2017) Alberto Salomone et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Synthetic Stimulant Reaching Epidemic Proportions: Flakka-induced ST-elevation Myocardial Infarction With Intracardiac Thrombi

(2017) Shane V. Cherry et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Active vaccination attenuates the psychostimulant effects of α-PVP and MDPV in rats

(2017) Jacques D. Nguyen et al.   NEUROPHARMACOLOGY

The Cathinones MDPV and α-PVP Elicit Different Behavioral and Molecular Effects Following Acute Exposure

(2017) Giuseppe Giannotti et al.   NEUROTOXICITY RESEARCH

Conditioned taste avoidance, conditioned place preference and hyperthermia induced by the second generation ‘bath salt’ α-pyrrolidinopentiophenone (α-PVP)

(2017) Katharine H. Nelson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Measuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay

(2017) Anne Zwartsen et al.   TOXICOLOGY IN VITRO

Cocaine-like discriminative stimulus effects of alpha-pyrrolidinovalerophenone, methcathinone and their 3,4-methylenedioxy or 4-methyl analogs in rhesus monkeys

(2016) Douglas A. Smith et al.   ADDICTION BIOLOGY

Neurobiology of 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

(2016) Richard A. Glennon et al.   BRAIN RESEARCH BULLETIN

Elimination half-life of alpha-pyrrolidinovalerophenone in an acute non-fatal intoxication

(2016) Loreto Quesada et al.   CLINICAL TOXICOLOGY

Clinical characteristics of α-pyrrolidinovalerophenone (α-PVP) poisoning

(2016) Rimako Umebachi et al.   CLINICAL TOXICOLOGY

Poisoning to α-pyrrolidinovalerophenone (α-PVP), a synthetic cathinone

(2016) Neel Patel et al.   CLINICAL TOXICOLOGY

Toxicity evaluation of α-pyrrolidinovalerophenone (α-PVP): results from intoxication cases within the STRIDA project

(2016) Olof Beck et al.   CLINICAL TOXICOLOGY

Comparative metabolism of tramadol and tapentadol: a toxicological perspective

(2016) Joana Barbosa et al.   DRUG METABOLISM REVIEWS

Metabolomics of methadone: clinical and forensic toxicological implications and variability of dose response

(2016) Ricardo Jorge Dinis-Oliveira   DRUG METABOLISM REVIEWS

Metabolomics of Δ9-tetrahydrocannabinol: implications in toxicity

(2016) Ricardo Jorge Dinis-Oliveira   DRUG METABOLISM REVIEWS

GC–MS analysis of the designer drug α-pyrrolidinovalerophenone and its metabolites in urine and blood in an acute poisoning case

(2016) Marcel Grapp et al.   FORENSIC SCIENCE INTERNATIONAL

New psychoactive substance α-PVP in a traffic accident case

(2016) Sebastian Rojek et al.   Forensic Toxicology

Blood concentrations of α-pyrrolidinovalerophenone (α-PVP) determined in 66 forensic samples

(2016) Piotr Adamowicz et al.   Forensic Toxicology

Chiral enantioresolution of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone (MDPV)

(2016) Bárbara Silva et al.   Forensic Toxicology

New psychoactive substances as part of polydrug abuse within opioid maintenance treatment revealed by comprehensive high-resolution mass spectrometric urine drug screening

(2016) Pertti Heikman et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Twenty-One Cases Involving Alpha-Pyrrolidinovalerophenone (α-PVP)

(2016) Trista Haupt Wright et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Identification and quantification of synthetic cathinones in blood and urine using liquid chromatography-quadrupole/time of flight (LC-Q/TOF) mass spectrometry

(2016) Lindsay Glicksberg et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fatal Intoxication with α-PVP, a Synthetic Cathinone Derivative

(2016) Barbara Potocka-Banaś et al.   JOURNAL OF FORENSIC SCIENCES

Identificación de la droga de abuso flakka (α-PVP) como sospecha de sumisión química no probada en Urgencias de un hospital terciario

(2016) Cesáreo Fernández Alonso et al.   MEDICINA CLINICA

Synthetic cathinone MDPV downregulates glutamate transporter subtype I (GLT-1) and produces rewarding and locomotor-activating effects that are reduced by a GLT-1 activator

(2016) Ryan A. Gregg et al.   NEUROPHARMACOLOGY

Pharmacological effects of methamphetamine and alpha-PVP vapor and injection

(2016) Julie A. Marusich et al.   NEUROTOXICOLOGY

Self-administration and behavioral economics of second-generation synthetic cathinones in male rats

(2016) S.L. Huskinson et al.   PSYCHOPHARMACOLOGY

The dangerous new synthetic drug α-PVP as the hydrated chloride salt α-pyrrolidinopentiophenone hydrochloride 0.786-hydrate

(2016) Matthew R. Wood et al.   Acta Crystallographica Section C-Structural Chemistry

Stereoselective Actions of Methylenedioxypyrovalerone (MDPV) To Inhibit Dopamine and Norepinephrine Transporters and Facilitate Intracranial Self-Stimulation in Rats

(2015) R. Kolanos et al.   ACS Chemical Neuroscience

Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters

(2015) R. Kolanos et al.   ACS Chemical Neuroscience

In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol

(2015) Noelia Negreira et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Alpha-pyrrolidinovalerophenone (alpha-PVP): Self-administration and acute drug challenges in rats

(2015) Shawn M. Aarde et al.   DRUG AND ALCOHOL DEPENDENCE

Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats

(2015) Jennifer E. Naylor et al.   DRUG AND ALCOHOL DEPENDENCE

The prevalence of new psychoactive substances in biological material - a three-year review of casework in Poland

(2015) Piotr Adamowicz et al.   Drug Testing and Analysis

Patterns of drug abuse among drug users with regular and irregular attendance for treatment as detected by comprehensive UHPLC-HR-TOF-MS

(2015) Mira Sundström et al.   Drug Testing and Analysis

Monoamine transporter and receptor interaction profiles of novel psychoactive substances: Para-halogenated amphetamines and pyrovalerone cathinones

(2015) Anna Rickli et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Injection of new psychoactive substance snow blow associated with recently acquired HIV infections among homeless people who inject drugs in Dublin, Ireland, 2015

(2015) Coralie Giese et al.   Eurosurveillance

Metabolism of the designer drug α-pyrrolidinobutiophenone (α-PBP) in humans: Identification and quantification of the phase I metabolites in urine

(2015) Shuntaro Matsuta et al.   FORENSIC SCIENCE INTERNATIONAL

Concentrations of MDPV in rat striatum correlate with the psychostimulant effect

(2015) Judith Novellas et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability

(2015) H. Chapy et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Effects of  -Pyrrolidinopentiophenone and 4-Methyl-N-Ethylcathinone, Two Synthetic Cathinones Commonly Found in Second-Generation "Bath Salts," on Intracranial Self-Stimulation Thresholds in Rats

(2015) L. R. Watterson et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone

(2014) Hisashi Nagai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Testing for Designer Stimulants: Metabolic Profiles of 16 Synthetic Cathinones Excreted Free in Human Urine

(2014) Victor Uralets et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Synthetic Cathinones (“Bath Salts”)

(2014) Matthew L. Banks et al.   JOURNAL OF EMERGENCY MEDICINE

New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron

(2014) Asuka Kaizaki et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Postmortem distribution of α-pyrrolidinobutiophenone in body fluids and solid tissues of a human cadaver

(2014) Amin Wurita et al.   Legal Medicine

Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)

(2014) Julie A. Marusich et al.   NEUROPHARMACOLOGY

In silico and in vitro metabolism studies support identification of designer drugs in human urine by liquid chromatography/quadrupole-time-of-flight mass spectrometry

(2013) Elli Tyrkkö et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Compartment Syndrome After “Bath Salts” Use: A Case Series

(2013) Michael Levine et al.   ANNALS OF EMERGENCY MEDICINE

Khat and synthetic cathinones: a review

(2013) Maria João Valente et al.   ARCHIVES OF TOXICOLOGY

Small Molecules as Chromatographic Tools for HPLC Enantiomeric Resolution: Pirkle-Type Chiral Stationary Phases Evolution

(2013) Carla Fernandes et al.   CHROMATOGRAPHIA

Toxicity and death following recreational use of 2-pyrrolidino valerophenone

(2013) Celine Eiden et al.   CLINICAL TOXICOLOGY

Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites

(2013) Noriaki Shima et al.   Forensic Toxicology

Time-course profile of urinary excretion of intravenously administered α-pyrrolidinovalerophenone and α-pyrrolidinobutiophenone in a human

(2013) Akira Namera et al.   Forensic Toxicology

Analysis of Synthetic Cathinones Commonly Found in Bath Salts in Human Performance and Postmortem Toxicology: Method Development, Drug Distribution and Interpretation of Results

(2013) L. J. Marinetti et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Simple segmental hair analysis for α-pyrrolidinophenone-type designer drugs by MonoSpin extraction for evaluation of abuse history

(2013) Akira Namera et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Methylenedioxypyrovalerone (“Bath Salts”),Related Death: Case Report and Review of the Literature,

(2013) Kilak Kesha et al.   JOURNAL OF FORENSIC SCIENCES

Pharmacological characterization of designer cathinonesin vitro

(2012) LD Simmler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Psychoactive “bath salts”: Not so soothing

(2012) Michael H. Baumann et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthetic cathinones: Chemistry, pharmacology and toxicology of a new class of designer drugs of abuse marketed as “bath salts” or “plant food”

(2012) M. Coppola et al.   TOXICOLOGY LETTERS

New designer drug α‐pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

(2009) Christoph Sauer et al.   JOURNAL OF MASS SPECTROMETRY