Versatile coordination of acetazolamide to ruthenium(ii) p-cymene complexes and preliminary cytotoxicity studies

Ruthenium(II)-Arene Metallacycles: Crystal Structures, Interaction with DNA, and Cytotoxicity

(2017) Hong-Yan Wang et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

(2017) Tatjana Lazarević et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium Complexes are pH-Activated Metallo Prodrugs (pHAMPs) with Light-Triggered Selective Toxicity Toward Cancer Cells

(2017) Fengrui Qu et al.   INORGANIC CHEMISTRY

Varying the metal to ethacrynic acid ratio in ruthenium(ii)/osmium(ii)- p -cymene conjugates

(2017) Emilia Păunescu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Advances in the design of organometallic anticancer complexes

(2017) Pingyu Zhang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Organometallic Glutathione S-Transferase Inhibitors

(2017) Emilia Păunescu et al.   ORGANOMETALLICS

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

The development of RAPTA compounds for the treatment of tumors

(2016) Benjamin S. Murray et al.   COORDINATION CHEMISTRY REVIEWS

Metal-based drugs that break the rules

(2016) Claire S. Allardyce et al.   DALTON TRANSACTIONS

“Head-to-head” double-hamburger-like structure of di-ruthenated d(GpG) adducts of mono-functional Ru–arene anticancer complexes

(2016) Hong-Ke Liu et al.   DALTON TRANSACTIONS

Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective

(2016) Enzo Alessio   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

RuII(η6-p-cymene) Complexes of Bioactive 1,2-Benzothiazines: Protein Binding vs. Antitumor Activity

(2016) Adnan Ashraf et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Nonsteroidal Anti-inflammatory—Organometallic Anticancer Compounds

(2016) Emilia Păunescu et al.   INORGANIC CHEMISTRY

From Sunscreen to Anticancer Agent: Ruthenium(II) Arene Avobenzone Complexes Display Potent Anticancer Activity

(2016) Riccardo Pettinari et al.   ORGANOMETALLICS

Nanoparticles of chitosan conjugated to organo-ruthenium complexes

(2016) Yanqing Wang et al.   Inorganic Chemistry Frontiers

Linking the future of anticancer metal-complexes to the therapy of tumour metastases

(2015) Alberta Bergamo et al.   CHEMICAL SOCIETY REVIEWS

Chemical biology of anticancer gold(iii) and gold(i) complexes

(2015) Taotao Zou et al.   CHEMICAL SOCIETY REVIEWS

Half-Sandwich Ruthenium(II) Biotin Conjugates as Biological Vectors to Cancer Cells

(2015) Maria V. Babak et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition studies and cellular imaging investigations

(2015) Jonathan R. Dilworth et al.   DALTON TRANSACTIONS

Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity

(2015) Alexey A. Nazarov et al.   DALTON TRANSACTIONS

Acetazolamide for the treatment of idiopathic intracranial hypertension

(2015) Claudiu T Supuran   Expert Review of Neurotherapeutics

Synthesis and Antiproliferative Activity of New Ruthenium Complexes with Ethacrynic-Acid-Modified Pyridine and Triphenylphosphine Ligands

(2015) Gabriele Agonigi et al.   INORGANIC CHEMISTRY

The history and rationale of using carbonic anhydrase inhibitors in the treatment of peptic ulcers. In memoriam Ioan Puşcaş (1932–2015)

(2015) György M. Buzás et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The 1,3-diaryltriazenido( p -cymene)ruthenium(II) complexes with a high in vitro anticancer activity

(2015) Jure Vajs et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Impact of the Halogen Substitution Pattern on the Biological Activity of Organoruthenium 8-Hydroxyquinoline Anticancer Agents

(2015) Mario Kubanik et al.   ORGANOMETALLICS

Strong in Vitro Cytotoxic Potential of New Ruthenium–Cymene Complexes

(2015) Stefan Nikolić et al.   ORGANOMETALLICS

S⋯O chalcogen bonding in sulfa drugs: insights from multipole charge density and X-ray wavefunction of acetazolamide

(2015) Sajesh P. Thomas et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design

(2015) Joan J. Soldevila-Barreda et al.   Nature Communications

Acetazolamide for the treatment of idiopathic intracranial hypertension

(2015) Claudiu T Supuran   Expert Review of Neurotherapeutics

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Combining [Arene-Ru] with Azocarboxamide to Generate a Complex with Cytotoxic Properties

(2014) Michael G. Sommer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium, Iridium, and Ruthenium Half-Sandwich Picolinamide Complexes as Anticancer Agents

(2014) Zahra Almodares et al.   INORGANIC CHEMISTRY

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

(2014) Suzanne Leijen et al.   INVESTIGATIONAL NEW DRUGS

Influence of PPh3 moiety in the anticancer activity of new organometallic ruthenium complexes

(2014) Rubén Sáez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Discovery of a Highly Tumor-Selective Organometallic Ruthenium(II)–Arene Complex

(2014) Catherine M. Clavel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium(II)–Arene RAPTA Type Complexes Containing Curcumin and Bisdemethoxycurcumin Display Potent and Selective Anticancer Activity

(2014) Riccardo Pettinari et al.   ORGANOMETALLICS

In vivo anti-tumor activity of the organometallic ruthenium(ii)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas

(2014) Andrea Weiss et al.   Chemical Science

NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

(2014) Robert Trondl et al.   Chemical Science

Conformational control of anticancer activity: the application of arene-linked dinuclear ruthenium(ii) organometallics

(2014) Benjamin S. Murray et al.   Chemical Science

Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

(2014) Zenita Adhireksan et al.   Nature Communications

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

(2013) Wolfgang Kandioller et al.   CHEMICAL COMMUNICATIONS

Recent advances in supramolecular and biological aspects of arene ruthenium(II) complexes

(2013) Ashish Kumar Singh et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis and evaluation of new polynuclear organometallic Ru(ii), Rh(iii) and Ir(iii) pyridyl ester complexes as in vitro antiparasitic and antitumor agents

(2013) Prinessa Chellan et al.   DALTON TRANSACTIONS

Multi-targeted organometallic ruthenium(II)–arene anticancer complexes bearing inhibitors of poly(ADP-ribose) polymerase-1: A strategy to improve cytotoxicity

(2013) Zhigang Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Opening the lid on piano-stool complexes: An account of ruthenium(II)–arene complexes with medicinal applications

(2013) Alexey A. Nazarov et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Enzyme inhibition by metal complexes: concepts, strategies and applications

(2013) Kelly J. Kilpin et al.   Chemical Science

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX

(2012) Daniel Can et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder

(2012) Andrea Kurzwernhart et al.   CHEMICAL COMMUNICATIONS

Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs

(2012) Vladimir B. Arion et al.   CHEMICAL COMMUNICATIONS

Designing organometallic compounds for catalysis and therapy

(2012) Anna Louisa Noffke et al.   CHEMICAL COMMUNICATIONS

Structure–Activity Relationships of Targeted RuII(η6-p-Cymene) Anticancer Complexes with Flavonol-Derived Ligands

(2012) Andrea Kurzwernhart et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural, spectroscopic and voltammetric studies of bis(acetazolamido)bis(aquo)bis(nicotinamide)copper(II)

(2012) Filiz Öztürk et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Physicochemical Studies and Anticancer Potency of Ruthenium η6-p-Cymene Complexes Containing Antibacterial Quinolones

(2011) Jakob Kljun et al.   ORGANOMETALLICS

A new vibrational study of Acetazolamide compound based on normal coordinate analysis and DFT calculations

(2010) S.A. Brandán et al.   JOURNAL OF MOLECULAR STRUCTURE

Rational Design of an Organometallic Glutathione Transferase Inhibitor

(2009) Wee Han Ang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)–arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity

(2009) Sanja Grgurić-Šipka et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

(2009) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Reactivity of [TpRuCl(PTA)(PPh3)] with Alkynes and Propargylic Alcohols: Occurrence of Structurally Related Cationic vs Neutral Allenylidene Complexes with the Ruthenium Hydrotris(pyrazolyl)borate Moiety

(2009) Sandra Bolaño et al.   ORGANOMETALLICS

In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands

(2008) Isabella Berger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Developments of Carbonic Anhydrase Inhibitors as Potential Anticancer Drugs

(2008) Anne Thiry et al.   JOURNAL OF MEDICINAL CHEMISTRY

Vibrational study of acetazolamide polymorphism

(2008) C. Baraldi et al.   JOURNAL OF MOLECULAR STRUCTURE

PGSE NMR Studies on RAPTA Derivatives: Evidence for the Formation of H-Bonded Dicationic Species

(2008) Sandra Bolaño et al.   ORGANOMETALLICS