Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity

Celebrating the New

(2017) Kimberly Callan   Journal of the National Comprehensive Cancer Network

Immuno-Chemotherapeutic Platinum(IV) Prodrugs of Cisplatin as Multimodal Anticancer Agents

(2014) Daniel Yuan Qiang Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reprogramming the Mechanism of Action of Chlorambucil by Coupling to a G-Quadruplex Ligand

(2014) Marco Di Antonio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

(2013) Wolfgang Kandioller et al.   CHEMICAL COMMUNICATIONS

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs

(2013) Christian G. Hartinger et al.   CHEMICAL SOCIETY REVIEWS

Opening the lid on piano-stool complexes: An account of ruthenium(II)–arene complexes with medicinal applications

(2013) Alexey A. Nazarov et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents

(2013) Samuel M. Meier et al.   Chemical Science

Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder

(2012) Andrea Kurzwernhart et al.   CHEMICAL COMMUNICATIONS

Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs

(2012) Vladimir B. Arion et al.   CHEMICAL COMMUNICATIONS

3-Hydroxyflavones vs. 3-hydroxyquinolinones: structure–activity relationships and stability studies on RuII(arene) anticancer complexes with biologically active ligands

(2012) Andrea Kurzwernhart et al.   DALTON TRANSACTIONS

Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death

(2012) Alexey A. Nazarov et al.   DALTON TRANSACTIONS

Anthracene-Tethered Ruthenium(II) Arene Complexes as Tools To Visualize the Cellular Localization of Putative Organometallic Anticancer Compounds

(2012) Alexey A. Nazarov et al.   INORGANIC CHEMISTRY

Structure–Activity Relationships of Targeted RuII(η6-p-Cymene) Anticancer Complexes with Flavonol-Derived Ligands

(2012) Andrea Kurzwernhart et al.   JOURNAL OF MEDICINAL CHEMISTRY

Naphthalimide-Tagged Ruthenium–Arene Anticancer Complexes: Combining Coordination with Intercalation

(2012) Kelly J. Kilpin et al.   ORGANOMETALLICS

Thermoresponsive Chlorambucil Derivatives for Tumour Targeting

(2011) Catherine M. Clavel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core

(2011) Bin Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bioorganometallics: Future Trends in Drug Discovery, Analytical Chemistry, and Catalysis†,‡

(2011) Elizabeth A. Hillard et al.   ORGANOMETALLICS

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA

(2009) Fabio Arnesano et al.   COORDINATION CHEMISTRY REVIEWS

Bioorganometallic chemistry—from teaching paradigms to medicinal applications

(2008) Christian G. Hartinger et al.   CHEMICAL SOCIETY REVIEWS

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands

(2008) Isabella Berger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antitumour metal compounds: more than theme and variations

(2007) Michael A. Jakupec et al.   DALTON TRANSACTIONS