Cohesin dynamic association to chromatin and interfacing with replication forks in genome integrity maintenance

Establishment of DNA-DNA Interactions by the Cohesin Ring

(2018) Yasuto Murayama et al.   CELL

Establishing and dissolving cohesion during the vertebrate cell cycle

(2018) Carmen Morales et al.   CURRENT OPINION IN CELL BIOLOGY

Cdc48/VCP Promotes Chromosome Morphogenesis by Releasing Condensin from Self-Entrapment in Chromatin

(2018) Yogitha Thattikota et al.   MOLECULAR CELL

Smc3 Deacetylation by Hos1 Facilitates Efficient Dissolution of Sister Chromatid Cohesion during Early Anaphase

(2017) Shuyu Li et al.   MOLECULAR CELL

Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress

(2017) Haiyun Gan et al.   MOLECULAR CELL

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

(2017) Christoph F. Kurat et al.   MOLECULAR CELL

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

(2017) Joseph T.P. Yeeles et al.   MOLECULAR CELL

Cohesin Ubiquitylation and Mobilization Facilitate Stalled Replication Fork Dynamics

(2017) Camilla Frattini et al.   MOLECULAR CELL

Structure of the cohesin loader Scc2

(2017) William C. H. Chao et al.   Nature Communications

Cohesin Can Remain Associated with Chromosomes during DNA Replication

(2017) James D.P. Rhodes et al.   Cell Reports

Cohesin mutations in human cancer

(2016) Victoria K. Hill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The loading of condensin in the context of chromatin

(2016) Xavier Robellet et al.   CURRENT GENETICS

A cohesin-based structural platform supporting homologous chromosome pairing in meiosis

(2016) Da-Qiao Ding et al.   CURRENT GENETICS

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

(2016) Catarina P. Samora et al.   MOLECULAR CELL

Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

(2016) Fabrizio Villa et al.   MOLECULAR CELL

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends

(2016) Camille Gelot et al.   MOLECULAR CELL

VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair

(2016) Johannes van den Boom et al.   MOLECULAR CELL

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together

(2016) Andrew Seeber et al.   MOLECULAR CELL

SMC complexes: from DNA to chromosomes

(2016) Frank Uhlmann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nucleolytic processing of aberrant replication intermediates by an Exo1-Dna2-Sae2 axis counteracts fork collapse-driven chromosome instability

(2016) Arianna Colosio et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into Ring Formation of Cohesin and Related Smc Complexes

(2016) Thomas Gligoris et al.   TRENDS IN CELL BIOLOGY

DNA Polymerases Divide the Labor of Genome Replication

(2016) Scott A. Lujan et al.   TRENDS IN CELL BIOLOGY

Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks

(2016) Cyril Ribeyre et al.   Cell Reports

Of Rings and Rods: Regulating Cohesin Entrapment of DNA to Generate Intra- and Intermolecular Tethers

(2016) Robert V. Skibbens   PLoS Genetics

DNA Entry into and Exit out of the Cohesin Ring by an Interlocking Gate Mechanism

(2015) Yasuto Murayama et al.   CELL

Error-Free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polα/Primase/Ctf4 Complex

(2015) Marco Fumasoni et al.   MOLECULAR CELL

Chromosome Dynamics during Mitosis

(2015) Tatsuya Hirano   Cold Spring Harbor Perspectives in Biology

Rad53-Mediated Regulation of Rrm3 and Pif1 DNA Helicases Contributes to Prevention of Aberrant Fork Transitions under Replication Stress

(2015) Silvia Emma Rossi et al.   Cell Reports

Etiology and pathogenesis of the cohesinopathies

(2015) Musinu Zakari et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Cohesin gene mutations in tumorigenesis: from discovery to clinical significance

(2014) David A. Solomon et al.   BMB Reports

Replication stress and cancer: It takes two to tango

(2014) Emilio Lecona et al.   EXPERIMENTAL CELL RESEARCH

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

(2014) Constance Alabert et al.   NATURE CELL BIOLOGY

Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication

(2014) Marija Maric et al.   SCIENCE

Structural insights into eukaryotic DNA replication

(2014) Sylvie Doublié et al.   Frontiers in Microbiology

Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks

(2013) Mari Fujita et al.   PLoS One

Pds5 promotes and protects cohesin acetylation

(2013) K.-L. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulating DNA Replication in Bacteria

(2013) K. Skarstad et al.   Cold Spring Harbor Perspectives in Biology

The DNA damage checkpoint response to replication stress: A Game of Forks

(2013) Rachel Jossen et al.   Frontiers in Genetics

Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18–RFC complex and Mrc1

(2012) Mong Sing Lai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cohesin: A guardian of genome integrity

(2012) Gunjan D. Mehta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

(2012) Kok-Lung Chan et al.   CELL

Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

(2012) Amaya Alzu et al.   CELL

Sister chromatid cohesion establishment occurs in concert with lagging strand synthesis

(2012) Soumya Rudra et al.   CELL CYCLE

Budding Yeast Wapl Controls Sister Chromatid Cohesion Maintenance and Chromosome Condensation

(2012) Lidia Lopez-Serra et al.   CURRENT BIOLOGY

Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres

(2012) Silvia Remeseiro et al.   EMBO JOURNAL

dNTP pools determine fork progression and origin usage under replication stress

(2012) Jérôme Poli et al.   EMBO JOURNAL

Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart

(2012) Mireille Tittel-Elmer et al.   MOLECULAR CELL

Replisome Stability at Defective DNA Replication Forks Is Independent of S Phase Checkpoint Kinases

(2012) Giacomo De Piccoli et al.   MOLECULAR CELL

Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin

(2012) Alexandra McAleenan et al.   NATURE

Phosphorylation-enabled binding of SGO1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin

(2012) Nico P. Dantuma et al.   TRENDS IN CELL BIOLOGY

The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores

(2011) Rodrigo Bermejo et al.   CELL

Cohesin: genomic insights into controlling gene transcription and development

(2011) Dale Dorsett   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

(2011) Rati Verma et al.   MOLECULAR CELL

Cohesin: a catenase with separate entry and exit gates?

(2011) Kim Nasmyth   NATURE CELL BIOLOGY

Cdc48: a power machine in protein degradation

(2011) Alexandra Stolz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hos1 Is a Lysine Deacetylase for the Smc3 Subunit of Cohesin

(2010) Bo Xiong et al.   CURRENT BIOLOGY

Cohesin ties up the genome

(2010) María Carretero et al.   CURRENT OPINION IN CELL BIOLOGY

A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion

(2010) Alexander Kurze et al.   EMBO JOURNAL

Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

(2010) Christina Bauerschmidt et al.   EXPERIMENTAL CELL RESEARCH

An Smc3 Acetylation Cycle Is Essential for Establishment of Sister Chromatid Cohesion

(2010) Frederic Beckouët et al.   MOLECULAR CELL

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Replication Factor C Complexes Play Unique Pro- and Anti-Establishment Roles in Sister Chromatid Cohesion

(2010) Marie E. Maradeo et al.   PLoS One

Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction

(2009) Takashi Sutani et al.   CURRENT BIOLOGY

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

(2009) Mireille Tittel-Elmer et al.   EMBO JOURNAL

Csm3, Tof1, and Mrc1 Form a Heterotrimeric Mediator Complex That Associates with DNA Replication Forks

(2009) Masashige Bando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Targets of the Eco1 Acetyltransferase Modulate Cohesion in S Phase and in Response to DNA Damage

(2009) Jill M. Heidinger-Pauli et al.   MOLECULAR CELL

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

(2009) M. Harreman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA