Of Rings and Rods: Regulating Cohesin Entrapment of DNA to Generate Intra- and Intermolecular Tethers

Genome stability: What we have learned from cohesinopathies

(2016) Francesco Cucco et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

(2016) Matthias Merkenschlager et al.   Annual Review of Genomics and Human Genetics

CTCF: making the right connections

(2016) Rodolfo Ghirlando et al.   GENES & DEVELOPMENT

Visualizing the Path of DNA through Proteins Using DREEM Imaging

(2016) Dong Wu et al.   MOLECULAR CELL

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening

(2016) Ahmed M.O. Elbatsh et al.   MOLECULAR CELL

Releasing Activity Disengages Cohesin’s Smc3/Scc1 Interface in a Process Blocked by Acetylation

(2016) Frederic Beckouët et al.   MOLECULAR CELL

Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic

(2016) Jorine M. Eeftens et al.   Cell Reports

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function

(2016) Kyle W. Muir et al.   Cell Reports

Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1

(2016) Byung-Gil Lee et al.   Cell Reports

Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin

(2016) Johannes Stigler et al.   Cell Reports

DNA Entry into and Exit out of the Cohesin Ring by an Interlocking Gate Mechanism

(2015) Yasuto Murayama et al.   CELL

Leukemogenic Activity of Cohesin Rings True

(2015) Mark S. Williams et al.   Cell Stem Cell

Esco2 regulatescx43expression during skeletal regeneration in the zebrafish fin

(2015) Rajeswari Banerji et al.   DEVELOPMENTAL DYNAMICS

Complex elaboration: making sense of meiotic cohesin dynamics

(2015) Susannah Rankin   FEBS Journal

Structural Basis for Dimer Formation of Human Condensin Structural Maintenance of Chromosome Proteins and Its Implications for Single-stranded DNA Recognition

(2015) Susumu Uchiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase

(2015) Vincent Guacci et al.   MOLECULAR BIOLOGY OF THE CELL

Interallelic complementation provides functional evidence for cohesin–cohesin interactions on DNA

(2015) Thomas Eng et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding

(2015) Young-Min Soh et al.   MOLECULAR CELL

Pds5 regulators segregate cohesion and condensation pathways inSaccharomyces cerevisiae

(2015) Kevin Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells

(2015) Sadia Rahman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Tailors: CTCF and Cohesin Shape the Genome During Evolution

(2015) Matteo Vietri Rudan et al.   TRENDS IN GENETICS

Chromosome Dynamics during Mitosis

(2015) Tatsuya Hirano   Cold Spring Harbor Perspectives in Biology

Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling

(2015) H. Barysz et al.   Open Biology

A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex

(2015) Ola Orgil et al.   PLoS Genetics

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

(2015) Gamze Çamdere et al.   eLife

Cohesin’s ATPase Activity Couples Cohesin Loading onto DNA with Smc3 Acetylation

(2014) Rene Ladurner et al.   CURRENT BIOLOGY

Structure and function of cohesin's Scc3/SA regulatory subunit

(2014) Maurici B. Roig et al.   FEBS LETTERS

Accessory Replicative Helicases and the Replication of Protein-Bound DNA

(2014) Jan-Gert Brüning et al.   JOURNAL OF MOLECULAR BIOLOGY

ROCC, a conserved region in cohesin's Mcd1 subunit, is essential for the proper regulation of the maintenance of cohesion and establishment of condensation

(2014) Thomas Eng et al.   MOLECULAR BIOLOGY OF THE CELL

Characterization of a DNA exit gate in the human cohesin ring

(2014) P. J. Huis in 't Veld et al.   SCIENCE

Closing the cohesin ring: Structure and function of its Smc3-kleisin interface

(2014) T. G. Gligoris et al.   SCIENCE

Cohesin at active genes: a unifying theme for cohesin and gene expression from model organisms to humans

(2013) Dale Dorsett et al.   CURRENT OPINION IN CELL BIOLOGY

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3–Scc1 gate

(2013) Johannes Buheitel et al.   EMBO JOURNAL

Chromosome segregation: how to open cohesin without cutting the ring?

(2013) Yasuto Murayama et al.   EMBO JOURNAL

Cohesin codes – interpreting chromatin architecture and the many facets of cohesin function

(2013) Soumya Rudra et al.   JOURNAL OF CELL SCIENCE

Biochemical reconstitution of topological DNA binding by the cohesin ring

(2013) Yasuto Murayama et al.   NATURE

Chl1 DNA Helicase Regulates Scc2 Deposition Specifically during DNA-Replication in Saccharomyces cerevisiae

(2013) Soumya Rudra et al.   PLoS One

Cohesinopathies of a Feather Flock Together

(2013) Robert V. Skibbens et al.   PLoS Genetics

Sister Chromatid Cohesion

(2012) J.-M. Peters et al.   Cold Spring Harbor Perspectives in Biology

Cohesin Rings Devoid of Scc3 and Pds5 Maintain Their Stable Association with the DNA

(2012) Irina Kulemzina et al.   PLoS Genetics

Diverse Developmental Disorders from The One Ring: Distinct Molecular Pathways Underlie the Cohesinopathies

(2012) Julia A. Horsfield et al.   Frontiers in Genetics

Cohesin-independent segregation of sister chromatids in budding yeast

(2011) Vincent Guacci et al.   MOLECULAR BIOLOGY OF THE CELL

Gene Regulation by Cohesin in Cancer: Is the Ring an Unexpected Party to Proliferation?

(2011) J. M. Rhodes et al.   MOLECULAR CANCER RESEARCH

The dark side of cohesin: The carcinogenic point of view

(2011) Linda Mannini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

In vitro assembly of physiological cohesin/DNA complexes

(2011) I. Onn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair

(2010) Jill M. Heidinger-Pauli et al.   CURRENT BIOLOGY

ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex

(2010) Bin Hu et al.   CURRENT BIOLOGY

Dosage-Sensitive Regulation of Cohesin Chromosome Binding and Dynamics by Nipped-B, Pds5, and Wapl

(2010) M. Gause et al.   MOLECULAR AND CELLULAR BIOLOGY

Cornelia de Lange syndrome, cohesin, and beyond

(2009) J Liu et al.   CLINICAL GENETICS

Road to the crossroads of life and death: Linking sister chromatid cohesion and separation to aneuploidy, apoptosis and cancer

(2009) Anil K. Panigrahi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction

(2009) Takashi Sutani et al.   CURRENT BIOLOGY

Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity

(2009) Benjamin D. Rowland et al.   MOLECULAR CELL

The Elg1-RFC Clamp-Loading Complex Performs a Role in Sister Chromatid Cohesion

(2009) Marie E. Maradeo et al.   PLoS One

The Coiled Coils of Cohesin Are Conserved in Animals, but Not In Yeast

(2009) Glenn E. White et al.   PLoS One

The Elg1 Clamp Loader Plays a Role in Sister Chromatid Cohesion

(2009) Oren Parnas et al.   PLoS One

Sister Chromatid Cohesion: A Simple Concept with a Complex Reality

(2008) Itay Onn et al.   Annual Review of Cell and Developmental Biology

A handcuff model for the cohesin complex

(2008) Nenggang Zhang et al.   JOURNAL OF CELL BIOLOGY

Cohesin Interaction with Centromeric Minichromosomes Shows a Multi-Complex Rod-Shaped Structure

(2008) Alexandra Surcel et al.   PLoS One