The interplay of histone H2B ubiquitination with budding and fission yeast heterochromatin

Recruitment and allosteric stimulation of a histone-deubiquitinating enzyme during heterochromatin assembly

(2017) Alexis Zukowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1

(2017) Valentin Flury et al.   MOLECULAR CELL

H2B ubiquitylation and the histone chaperone Asf1 cooperatively mediate the formation and maintenance of heterochromatin silencing

(2017) Meng-Ying Wu et al.   NUCLEIC ACIDS RESEARCH

A common strategy for initiating the transition from proliferation to quiescence

(2016) Shawna Miles et al.   CURRENT GENETICS

Epigenetic transcriptional memory

(2016) Agustina D’Urso et al.   CURRENT GENETICS

The RNA-induced transcriptional silencing complex targets chromatin exclusively via interacting with nascent transcripts

(2016) Yukiko Shimada et al.   GENES & DEVELOPMENT

The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6

(2016) S. Branden Van Oss et al.   MOLECULAR CELL

Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers

(2016) Gregory Segala et al.   MOLECULAR CELL

Ubiquitin utilizes an acidic surface patch to alter chromatin structure

(2016) Galia T Debelouchina et al.   Nature Chemical Biology

Structural basis for histone H2B deubiquitination by the SAGA DUB module

(2016) M. T. Morgan et al.   SCIENCE

Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA

(2016) Vanesa Álvarez et al.   Scientific Reports

Structural and biochemical analyses of monoubiquitinated human histones H2B and H4

(2016) Shinichi Machida et al.   Open Biology

Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes

(2016) Reza Behrouzi et al.   eLife

The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast

(2015) L. Sadeghi et al.   EMBO REPORTS

A Conserved Deubiquitinating Enzyme Uses Intrinsically Disordered Regions to Scaffold Multiple Protein Interaction Sites

(2015) Benjamin J. Reed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Paf1 complex represses small-RNA-mediated epigenetic gene silencing

(2015) Katarzyna Maria Kowalik et al.   NATURE

Layers of DUB regulation

(2015) Danny D. Sahtoe et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNAi and Heterochromatin Assembly

(2015) Robert Martienssen et al.   Cold Spring Harbor Perspectives in Biology

Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin

(2015) Michelle L. Larin et al.   PLoS Genetics

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

(2014) H. Vlaming et al.   EMBO REPORTS

SIR Proteins and the Assembly of Silent Chromatin in Budding Yeast

(2013) Stephanie Kueng et al.   Annual Review of Genetics

Cellular aging is associated with increased ubiquitylation of histone H2B in yeast telomeric heterochromatin

(2013) Byung-Ho Rhie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIR–nucleosome interactions: Structure–function relationships in yeast silent chromatin

(2013) Mariano Oppikofer et al.   GENE

Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA

(2013) F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin

(2012) T. Kitada et al.   GENES & DEVELOPMENT

Histone H2B Ubiquitylation Promotes Activity of the Intact Set1 Histone Methyltransferase Complex in Fission Yeast

(2012) Ariane Racine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for H2B Ubiquitylation in DNA Replication

(2012) Kelly M. Trujillo et al.   MOLECULAR CELL

A Conserved Deubiquitinating Enzyme Controls Cell Growth by Regulating RNA Polymerase I Stability

(2012) Lauren A. Richardson et al.   Cell Reports

Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae

(2012) Alfonso Gallego-Sánchez et al.   PLoS Genetics

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin

(2011) Mariano Oppikofer et al.   EMBO JOURNAL

Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123

(2011) J. M. Schulze et al.   GENES & DEVELOPMENT

Genome-wide function of H2B ubiquitylation in promoter and genic regions

(2011) K. Batta et al.   GENES & DEVELOPMENT

Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79

(2011) S. Ehrentraut et al.   GENES & DEVELOPMENT

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution

(2011) K.-J. Armache et al.   SCIENCE

A Global Census of Fission Yeast Deubiquitinating Enzyme Localization and Interaction Networks Reveals Distinct Compartmentalization Profiles and Overlapping Functions in Endocytosis and Polarity

(2010) Ilektra Kouranti et al.   PLOS BIOLOGY

TERRA: telomeric repeat-containing RNA

(2009) Brian Luke et al.   EMBO JOURNAL

Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing

(2009) Aaron Johnson et al.   MOLECULAR CELL

The establishment of gene silencing at single-cell resolution

(2009) Erin A Osborne et al.   NATURE GENETICS

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone chaperone Chz1p regulates H2B ubiquitination and subtelomeric anti-silencing

(2009) Yakun Wan et al.   NUCLEIC ACIDS RESEARCH

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

(2009) M. B. Chandrasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL