Benchmark dose (BMD) modeling: current practice, issues, and challenges

Derivation of an oral toxicity reference value for nickel

(2017) Lynne T. Haber et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Dose-Response Modeling with Summary Data from Developmental Toxicity Studies

(2016) John F. Fox et al.   RISK ANALYSIS

A Unified Probabilistic Framework for Dose–Response Assessment of Human Health Effects

(2015) Weihsueh A. Chiu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Model Averaging Software for Dichotomous Dose Response Risk Estimation

(2015) Matthew W. Wheeler et al.   Journal of Statistical Software

Benchmark dose and the three Rs. Part II. Consequences for study design and animal use

(2014) Wout Slob   CRITICAL REVIEWS IN TOXICOLOGY

Benchmark dose and the three Rs. Part I. Getting more information from the same number of animals

(2014) Wout Slob   CRITICAL REVIEWS IN TOXICOLOGY

The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

(2014) Ted W. Simon et al.   CRITICAL REVIEWS IN TOXICOLOGY

Current modeling practice may lead to falsely high benchmark dose estimates

(2014) Joakim Ringblom et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Shape and steepness of toxicological dose–response relationships of continuous endpoints

(2013) Wout Slob et al.   CRITICAL REVIEWS IN TOXICOLOGY

Information-theoretic model-averaged benchmark dose analysis in environmental risk assessment

(2013) Walter W. Piegorsch et al.   ENVIRONMETRICS

Benchmark Dose Analysis via Nonparametric Regression Modeling

(2013) Walter W. Piegorsch et al.   RISK ANALYSIS

Hazard characterization of 3-MCPD using benchmark dose modeling: Factors influencing the outcome

(2012) Klaus Abraham et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Refined hazard characterization of 3-MCPD using benchmark dose modeling

(2012) Ivonne M. C. M. Rietjens et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Linear low-dose extrapolation for noncancer health effects is the exception, not the rule

(2011) Lorenz R. Rhomberg et al.   CRITICAL REVIEWS IN TOXICOLOGY

A Signal-to-Noise Crossover Dose as the Point of Departure for Health Risk Assessment

(2011) Salomon Sand et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Carcinogenicity study of 3-monochloropropane-1,2-diol in Sprague–Dawley rats

(2008) Wan-Seob Cho et al.   FOOD AND CHEMICAL TOXICOLOGY

Evidence-based dose–response assessment for thyroid tumorigenesis from acrylamide

(2008) Michael Dourson et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Toxicity value for 3-monochloropropane-1,2-diol using a benchmark dose methodology

(2008) Myungsil Hwang et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY