Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

(2013) Tatiana Afrikanova et al.   PLoS One

The Effect of Antihistamines on Seizures Induced by Increasing-Current Electroshocks: Ketotifen, but Not Olopatadine, Promotes the Seizures in Infant Rats

(2012) Koji Yamada et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Distinct models of induced hyperactivity in zebrafish larvae

(2012) Lee David Ellis et al.   BRAIN RESEARCH

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

(2012) S. Baxendale et al.   Disease Models & Mechanisms

Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome

(2012) Dezhi Cao et al.   EPILEPSIA

ESPERA study: Applicability of the new ILAE criteria for antiepileptic drug resistance of focal epilepsies in current clinical practice

(2012) Bertrand de Toffol et al.   EPILEPSY & BEHAVIOR

SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome

(2012) Alex C. Bender et al.   EPILEPSY & BEHAVIOR

Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models

(2012) Adriana Monserrath Orellana-Paucar et al.   EPILEPSY & BEHAVIOR

A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors

(2012) Robert F. Hunt et al.   EXPERIMENTAL NEUROLOGY

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

(2012) C. S. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Zebrafish: A Powerful Platform for In Vivo, HTS Drug Discovery

(2011) Chris Delvecchio et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The developing zebrafish (Danio rerio): A vertebrate model for high-throughput screening of chemical libraries

(2011) Charles A. Lessman   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Towards an integrated view of HCN channel role in epilepsy

(2011) Yoav Noam et al.   CURRENT OPINION IN NEUROBIOLOGY

Expression and function of KCNQ channels in larval zebrafish

(2011) Sally W. Chege et al.   Developmental Neurobiology

Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma

(2011) Wolfgang Löscher et al.   EPILEPSIA

Automated measurement of zebrafish larval movement

(2011) Clinton L. Cario et al.   JOURNAL OF PHYSIOLOGY-LONDON

Seizure-modifying potential of histamine H1 antagonists: A clinical observation

(2011) Ippei Miyata et al.   PEDIATRICS INTERNATIONAL

Reduced Sodium Channel Nav1.1 Levels in BACE1-null Mice

(2010) Doo Yeon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous Seizures and Altered Gene Expression in GABA Signaling Pathways in a mind bomb Mutant Zebrafish

(2010) G. A. Hortopan et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Localization and Genetic Perturbation of Saccade-Generating Neurons in Zebrafish

(2010) P. J. Schoonheim et al.   JOURNAL OF NEUROSCIENCE

NaV1.1 channels and epilepsy

(2010) William A. Catterall et al.   JOURNAL OF PHYSIOLOGY-LONDON

Zebrafish: An integrative system for neurogenomics and neurosciences

(2010) Silke Rinkwitz et al.   PROGRESS IN NEUROBIOLOGY

Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy

(2009) J. C. Oakley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

(2008) Shirit Einav et al.   NATURE BIOTECHNOLOGY

Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs

(2008) Matthew J. Winter et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS