Beyond the Magic Bullet: Current Progress of Therapeutic Vaccination in Multiple Sclerosis

Effects of ATX-MS-1467 immunotherapy over 16 weeks in relapsing multiple sclerosis

(2018) Jeremy Chataway et al.   NEUROLOGY

Shuttling Tolerogenic Dendritic Cells across the Blood–Brain Barrier In Vitro via the Introduction of De Novo C–C Chemokine Receptor 5 Expression Using Messenger RNA Electroporation

(2018) Maxime De Laere et al.   Frontiers in Immunology

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

(2016) G M Bell et al.   ANNALS OF THE RHEUMATIC DISEASES

Cryopreserved vitamin D3-tolerogenic dendritic cells pulsed with autoantigens as a potential therapy for multiple sclerosis patients

(2016) María José Mansilla et al.   Journal of Neuroinflammation

Administration of Myelin Basic Protein Peptides Encapsulated in Mannosylated Liposomes Normalizes Level of Serum TNF-αand IL-2 and Chemoattractants CCL2 and CCL4 in Multiple Sclerosis Patients

(2016) Yakov Lomakin et al.   MEDIATORS OF INFLAMMATION

CD206-Targeted Liposomal Myelin Basic Protein Peptides in Patients with Multiple Sclerosis Resistant to First-Line Disease-Modifying Therapies: A First-in-Human, Proof-of-Concept Dose-Escalation Study

(2016) Alexey Belogurov et al.   Neurotherapeutics

A basic overview of multiple sclerosis immunopathology

(2015) N. Grigoriadis et al.   EUROPEAN JOURNAL OF NEUROLOGY

Intraperitoneal Administration of Autologous Tolerogenic Dendritic Cells for Refractory Crohn’s Disease: A Phase I Study

(2015) Aranzazu Jauregui-Amezaga et al.   Journal of Crohns & Colitis

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

(2015) Helen Benham et al.   Science Translational Medicine

Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis

(2015) Annie Elong Ngono et al.   Journal of Immunology Research

Beneficial Effect of Tolerogenic Dendritic Cells Pulsed with MOG Autoantigen in Experimental Autoimmune Encephalomyelitis

(2014) María José Mansilla et al.   CNS Neuroscience & Therapeutics

Tolerogenic dendritic cell vaccines to treat autoimmune diseases: Can the unattainable dream turn into reality?

(2013) Ilse Van Brussel et al.   AUTOIMMUNITY REVIEWS

Regulatory dendritic cell therapy: From rodents to clinical application

(2013) Dalia Raïch-Regué et al.   IMMUNOLOGY LETTERS

Antigen-Specific Tolerance by Autologous Myelin Peptide-Coupled Cells: A Phase 1 Trial in Multiple Sclerosis

(2013) A. Lutterotti et al.   Science Translational Medicine

Transdermal Application of Myelin Peptides in Multiple Sclerosis Treatment

(2013) Agata Walczak et al.   JAMA Neurology

Personalized medicine in multiple sclerosis: hope or reality?

(2012) Tobias Derfuss   BMC Medicine

Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

(2012) C. M. U. Hilkens et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

T Cell Vaccination Benefits Relapsing Progressive Multiple Sclerosis Patients: A Randomized, Double-Blind Clinical Trial

(2012) Dimitrios Karussis et al.   PLoS One

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

(2011) N. Giannoukakis et al.   DIABETES CARE

A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS

(2011) M. S. Freedman et al.   NEUROLOGY

Immune regulation of multiple sclerosis by transdermally applied myelin peptides

(2010) Maciej Juryńczyk et al.   ANNALS OF NEUROLOGY

DNA-based vaccines for multiple sclerosis: Current status and future directions

(2010) Nicolas Fissolo et al.   CLINICAL IMMUNOLOGY

Specific T-cell proliferation to myelin peptides in relapsing-remitting multiple sclerosis

(2010) L. Grau-López et al.   EUROPEAN JOURNAL OF NEUROLOGY

Limited Amounts of Dendritic Cells Migrate into the T-Cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients

(2009) P. Verdijk et al.   CLINICAL CANCER RESEARCH

Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice

(2009) Dae-Seog Lim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis

(2008) Hideki Garren et al.   ANNALS OF NEUROLOGY

DNA-based vaccines: the future of multiple sclerosis therapy?

(2008) Olaf Stüve et al.   Expert Review of Neurotherapeutics

Therapeutic peptide vaccines for treatment of autoimmune diseases

(2008) David C. Wraith   IMMUNOLOGY LETTERS

A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy

(2008) Justin M. Skripak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Antigen-specific therapies in MS — Current concepts and novel approaches

(2008) Andreas Lutterotti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis

(2007) Arthur A. Vandenbark et al.   IMMUNOLOGY