Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-κB signalling pathways

(2012) J. Zheng et al.   ALLERGY

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin

(2012) Joyce J. B. C. van Beers et al.   ARTHRITIS AND RHEUMATISM

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy

(2012) J. B. Canavan et al.   BLOOD

Tolerogenic dendritic cells

(2012) Gaelle Beriou et al.   Current Opinion in Organ Transplantation

Stable antigen-specific T-cell hyporesponsiveness induced by tolerogenic dendritic cells from multiple sclerosis patients

(2012) Dàlia Raϊch-Regué et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis

(2012) Rong Li et al.   Journal of Translational Medicine

The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells

(2012) Silvia Gregori et al.   Frontiers in Immunology

Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models?

(2011) J. N. Stoop et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction — A comparative study of human clinical-applicable DC

(2011) Martine A. Boks et al.   CLINICAL IMMUNOLOGY

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

(2011) N. Giannoukakis et al.   DIABETES CARE

Dendritic cell control of tolerogenic responses

(2011) Santhakumar Manicassamy et al.   IMMUNOLOGICAL REVIEWS

Intra-graft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation

(2011) Felix Bohne et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt5a Skews Dendritic Cell Differentiation to an Unconventional Phenotype with Tolerogenic Features

(2011) Jaris Valencia et al.   JOURNAL OF IMMUNOLOGY

Weak CD4+ T-cell responses to citrullinated vimentin in rheumatoid arthritis patients carrying HLA-DR9 alleles

(2011) Diego Catalán et al.   RHEUMATOLOGY INTERNATIONAL

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Tolerogenic dendritic cells and their role in transplantation

(2011) Mohamed Ezzelarab et al.   SEMINARS IN IMMUNOLOGY

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

(2010) R. A. Harry et al.   ANNALS OF THE RHEUMATIC DISEASES

HLA-DR1001 presents “altered-self” peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

(2010) Eddie A. James et al.   ARTHRITIS AND RHEUMATISM

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

(2010) Jeroen N. Stoop et al.   ARTHRITIS AND RHEUMATISM

Development of Dendritic Cell-Based Immunotherapy for Autoimmunity

(2010) Catharien M. U. Hilkens et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Peptides Presented by HLA-DR Molecules in Synovia of Patients with Rheumatoid Arthritis or Antibiotic-Refractory Lyme Arthritis

(2010) Robert J. Seward et al.   MOLECULAR & CELLULAR PROTEOMICS

Cartilage proteoglycan aggrecan epitopes induce proinflammatory autoreactive T-cell responses in rheumatoid arthritis and osteoarthritis

(2009) H de Jong et al.   ANNALS OF THE RHEUMATIC DISEASES

Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis

(2009) H. M. Baldwin et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models

(2009) Nicole R. Bianco et al.   ARTHRITIS AND RHEUMATISM

Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis

(2009) Alexei von Delwig et al.   ARTHRITIS AND RHEUMATISM

Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis

(2009) Anouk L. Feitsma et al.   ARTHRITIS AND RHEUMATISM

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

(2009) K. R. Carson et al.   BLOOD

Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice

(2009) Dae-Seog Lim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Therapeutic agents for patients with rheumatoid arthritis and an inadequate response to tumour necrosis factor-α antagonists

(2009) John D Isaacs   EXPERT OPINION ON BIOLOGICAL THERAPY

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmacytoid Dendritic Cells Mediate Oral Tolerance

(2008) Anne Goubier et al.   IMMUNITY

Determination of T-cell fate by dendritic cells

(2008) Sandra S Diebold   IMMUNOLOGY AND CELL BIOLOGY

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells

(2008) Amy E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells

(2008) A. E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis

(2008) A.W. Morgan et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology