Differential Reactivity of Metal Binding Domains of Copper ATPases towards Cisplatin and Colocalization of Copper and Platinum

A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

(2017) Sha Zhu et al.   Journal of Cancer

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics

(2016) Kyung Chan Park et al.   Metallomics

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

(2016) Cristine L. Chisholm et al.   Oncotarget

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Cisplatin binds to human copper chaperone Cox17: the mechanistic implication of drug delivery to mitochondria

(2014) Linhong Zhao et al.   CHEMICAL COMMUNICATIONS

Transporting platinum drugs from a copper chaperone to ATPase: the mechanistic implication of drug efflux mediated cisplatin resistance

(2014) Dechen Xu et al.   Inorganic Chemistry Frontiers

Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B

(2013) Francesco Tadini-Buoninsegni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

(2013) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1

(2013) Zhaoyong Xi et al.   CHEMICAL COMMUNICATIONS

Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

(2013) Maria E. Palm-Espling et al.   PLoS One

The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin

(2012) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

P-Type ATPases

(2011) Michael G. Palmgren et al.   Annual Review of Biophysics

Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) Oleg Y. Dmitriev   Biochemistry and Cell Biology

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

(2009) L. S. Mangala et al.   CLINICAL CANCER RESEARCH

Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

(2008) Ganna V Kalayda et al.   BMC CANCER

Conserved residues modulate copper release in human copper chaperone Atox1

(2008) F. Hussain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA