C(sp3 )−H Cyanation Promoted by Visible-Light Photoredox/Phosphate Hybrid Catalysis

Sulfonamides as new hydrogen atom transfer (HAT) catalysts for photoredox allylic and benzylic C–H arylations

(2018) Hirotaka Tanaka et al.   CHEMICAL COMMUNICATIONS

A General Strategy for Aliphatic C–H Functionalization Enabled by Organic Photoredox Catalysis

(2018) Kaila A. Margrey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular Anti-Markovnikov Hydroamination of Unactivated Alkenes with Sulfonamides Enabled by Proton-Coupled Electron Transfer

(2018) Qilei Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen Atom Transfer (HAT): A Versatile Strategy for Substrate Activation in Photocatalyzed Organic Synthesis

(2017) Luca Capaldo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct Aldehyde C–H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis

(2017) Xiaheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced Nickel-Catalyzed Chemo- and Regioselective Hydroalkylation of Internal Alkynes with Ether and Amide α-Hetero C(sp3)–H Bonds

(2017) Hong-Ping Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybrid Catalysis Enabling Room-Temperature Hydrogen Gas Release from N-Heterocycles and Tetrahydronaphthalenes

(2017) Shota Kato et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective sp3 C–H alkylation via polarity-match-based cross-coupling

(2017) Chip Le et al.   NATURE

Photocatalytic α-Acylation of Ethers

(2017) Zhongdong Sun et al.   ORGANIC LETTERS

Room temperature decarboxylative cyanation of carboxylic acids using photoredox catalysis and cyanobenziodoxolones: a divergent mechanism compared to alkynylation

(2017) Franck Le Vaillant et al.   Chemical Science

Mild, visible light-mediated decarboxylation of aryl carboxylic acids to access aryl radicals

(2017) L. Candish et al.   Chemical Science

Photoredox-Mediated Routes to Radicals: The Value of Catalytic Radical Generation in Synthetic Methods Development

(2017) Jennifer K. Matsui et al.   ACS Catalysis

Accelerated Discovery in Photocatalysis using a Mechanism-Based Screening Method

(2016) Matthew N. Hopkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Enantioselective C(sp3 )−H Functionalization

(2016) Qingquan Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deboronative cyanation of potassium alkyltrifluoroborates via photoredox catalysis

(2016) Jian-Jun Dai et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Visible-Light-Mediated Alkenylation, Allylation, and Cyanation of Potassium Alkyltrifluoroborates with Organic Photoredox Catalysts

(2016) Drew R. Heitz et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Promoted Activation of Unactivated C(sp3)–H Bonds and Their Selective Trifluoromethylthiolation

(2016) Satobhisha Mukherjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photochemical Nickel-Catalyzed C–H Arylation: Synthetic Scope and Mechanistic Investigations

(2016) Drew R. Heitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C(sp3)–H Cross Coupling Enabled by Catalytic Generation of Chlorine Radicals

(2016) Benjamin J. Shields et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Advances in C–CN Bond Formation via C–H Bond Activation

(2016) Yuanyuan Ping et al.   ACS Catalysis

Aerobic Oxidation of Benzylic sp3 C−H Bonds through Cooperative Visible-Light Photoredox Catalysis of N -Hydroxyimide and Dicyanopyrazine

(2016) Xinfei Liu et al.   Asian Journal of Organic Chemistry

Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations

(2015) Chao Liu et al.   CHEMICAL REVIEWS

Alcohols as alkylating agents in heteroarene C–H functionalization

(2015) Jian Jin et al.   NATURE

The direct arylation of allylic sp3 C–H bonds via organic and photoredox catalysis

(2015) James D. Cuthbertson et al.   NATURE

O-H hydrogen bonding promotes H-atom transfer from   C-H bonds for C-alkylation of alcohols

(2015) J. L. Jeffrey et al.   SCIENCE

Characterizing chain processes in visible light photoredox catalysis

(2015) Megan A. Cismesia et al.   Chemical Science

Thiyl Radicals in Organic Synthesis

(2014) Fabrice Dénès et al.   CHEMICAL REVIEWS

Gold-catalyzed C(sp3)–H bond functionalization

(2014) Jin Xie et al.   CHEMICAL SOCIETY REVIEWS

Activation of C–H Bonds via the Merger of Photoredox and Organocatalysis: A Coupling of Benzylic Ethers with Schiff Bases

(2014) Dominik Hager et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Photoinduced Direct Cyanation of C(sp3)-H Bonds

(2013) Masayuki Inoue et al.   SYNTHESIS-STUTTGART

Direct Formation of the C5′-Radical in the Sugar–Phosphate Backbone of DNA by High-Energy Radiation

(2012) Amitava Adhikary et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Redox-Neutral α-Cyanation of Amines

(2012) Longle Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic aerobic production of imines en route to mild, green, and concise derivatizations of amines

(2012) Toshiaki Sonobe et al.   Chemical Science

Innate and Guided C–H Functionalization Logic

(2011) Tobias Brückl et al.   ACCOUNTS OF CHEMICAL RESEARCH

Visible-light photoredox catalyzed oxidative Strecker reaction

(2011) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Tropylium Ion Mediated α-Cyanation of Amines

(2011) Julia M. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H functionalization of tertiary amines by cross dehydrogenative coupling reactions: solvent-free synthesis of α-aminonitriles and β-nitroamines under aerobic condition

(2011) Kaliyamoorthy Alagiri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Eosin Y Catalyzed Visible Light Oxidative C–C and C–P bond Formation

(2011) Durga Prasad Hari et al.   ORGANIC LETTERS

Photochemically Induced Radical Transformation of C(sp3)–H Bonds to C(sp3)–CN Bonds

(2011) Shin Kamijo et al.   ORGANIC LETTERS

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron catalyzed oxidative cyanation of tertiary amines

(2009) Wei Han et al.   CHEMICAL COMMUNICATIONS

An efficient aerobic oxidative cyanation of tertiary amines with sodium cyanide using vanadium based systems as catalysts

(2009) Sweety Singhal et al.   CHEMICAL COMMUNICATIONS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective Functionalization of sp3C−H Bonds Adjacent to Nitrogen Using (Diacetoxyiodo)benzene (DIB)

(2009) Xing-Zhong Shu et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Oxidative Cyanation of Tertiary Amines with Molecular Oxygen or Hydrogen Peroxide and Sodium Cyanide: sp3C−H Bond Activation and Carbon−Carbon Bond Formation

(2008) Shun-Ichi Murahashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Oxidative Cyanation Based on the Concept of Site Isolation

(2008) Toshiki Tajima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE

The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA

(2007) Peter C. Dedon   CHEMICAL RESEARCH IN TOXICOLOGY