Room temperature decarboxylative cyanation of carboxylic acids using photoredox catalysis and cyanobenziodoxolones: a divergent mechanism compared to alkynylation

Cyclic Hypervalent Iodine Reagents for Atom-Transfer Reactions: Beyond Trifluoromethylation

(2016) Yifan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deboronative cyanation of potassium alkyltrifluoroborates via photoredox catalysis

(2016) Jian-Jun Dai et al.   CHEMICAL COMMUNICATIONS

Carbon–Carbon Bond Forming Reactions via Photogenerated Intermediates

(2016) Davide Ravelli et al.   CHEMICAL REVIEWS

Advances in Synthetic Applications of Hypervalent Iodine Compounds

(2016) Akira Yoshimura et al.   CHEMICAL REVIEWS

A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light: Application to the Synthesis of Tetraponerines and Crispine A

(2016) Julio Cesar Orejarena Pacheco et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure Property Relationships of Carboxylic Acid Isosteres

(2016) Pierrik Lassalas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

(2016) Guo-Xing Li et al.   Chemical Science

Advances in C–CN Bond Formation via C–H Bond Activation

(2016) Yuanyuan Ping et al.   ACS Catalysis

α-Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non-Toxic Cyanide Source

(2015) Alexander M. Nauth et al.   ADVANCED SYNTHESIS & CATALYSIS

DDQ-mediated Direct C(sp3)H Cyanation of Benzyl Ethers and 1,3-Diarylpropenes under Solvent- and Metal-free Conditions

(2015) Shanshan Kong et al.   ADVANCED SYNTHESIS & CATALYSIS

Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents

(2015) Franck Le Vaillant et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Single Enzyme Transforms a Carboxylic Acid into a Nitrile through an Amide Intermediate

(2015) Micah T. Nelp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decarboxylative Alkynylation and Carbonylative Alkynylation of Carboxylic Acids Enabled by Visible-Light Photoredox Catalysis

(2015) Quan-Quan Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Induced Decarboxylative Functionalization of Carboxylic Acids and Their Derivatives

(2015) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Merging Photoredox and Nickel Catalysis: Decarboxylative Cross-Coupling of Carboxylic Acids with Vinyl Halides

(2015) Adam Noble et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Fluorination of Aliphatic Carboxylic Acids via Photoredox Catalysis

(2015) Sandrine Ventre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The direct electrophilic cyanation of β-keto esters and amides with cyano benziodoxole

(2015) Yao-Feng Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organic base-promoted enantioselective electrophilic cyanation of β-keto esters by using chiral phase-transfer catalysts

(2015) Min Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of Homoallylic Azides and Nitriles via Palladium-Catalyzed Decarboxylative Allylation

(2015) Maria Victoria Vita et al.   ORGANIC LETTERS

Sequential Oxidative α-Cyanation/Anti-Markovnikov Hydroalkoxylation of Allylamines

(2015) Alexander Wagner et al.   ORGANIC LETTERS

Alkynylation of Thiols with Ethynylbenziodoxolone (EBX) Reagents: α- or β- π-Addition?

(2015) Matthew D. Wodrich et al.   ORGANIC LETTERS

Rhodium-Catalyzed Cyanation of C(sp2)–H Bond of Alkenes

(2015) Manthena Chaitanya et al.   ORGANIC LETTERS

Synthesis of Vildagliptin Utilizing Continuous Flow and Batch Technologies

(2015) Laurent Pellegatti et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Towards an asymmetric organocatalytic α-cyanation of β-ketoesters

(2015) Raghunath Chowdhury et al.   TETRAHEDRON LETTERS

Direct oxidative cyanation of tertiary amines promoted by in situ generated hypervalent iodine(III)-CN intermediate

(2015) Hang Shen et al.   TETRAHEDRON LETTERS

Direct Approaches to Nitriles via Highly Efficient Nitrogenation Strategy through C–H or C–C Bond Cleavage

(2014) Teng Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cobalt-Catalyzed CH Cyanation of Arenes and Heteroarenes

(2014) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed RegioselectiveorthoCH Cyanation of Vinylarenes

(2014) Yang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron(II)-Catalyzed Direct Cyanation of Arenes with Aryl(cyano)iodonium Triflates

(2014) Zhibin Shu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General and Practical Formation of Thiocyanates from Thiols

(2014) Reto Frei et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct C–F Bond Formation Using Photoredox Catalysis

(2014) Montserrat Rueda-Becerril et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Arylation of α-Amino Acids via Photoredox Catalysis: A One-Step Conversion of Biomass to Drug Pharmacophore

(2014) Zhiwei Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carboxylic Acids as A Traceless Activation Group for Conjugate Additions: A Three-Step Synthesis of (±)-Pregabalin

(2014) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fast and Highly Chemoselective Alkynylation of Thiols with Hypervalent Iodine Reagents Enabled through a Low Energy Barrier Concerted Mechanism

(2014) Reto Frei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Co(III)-Catalyzed C–H Activation/Formal SN-Type Reactions: Selective and Efficient Cyanation, Halogenation, and Allylation

(2014) Da-Gang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocatalytic Decarboxylative Reduction of Carboxylic Acids and Its Application in Asymmetric Synthesis

(2014) Carlo Cassani et al.   ORGANIC LETTERS

Solar Synthesis: Prospects in Visible Light Photocatalysis

(2014) D. M. Schultz et al.   SCIENCE

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

Nitrile Synthesis through Catalyzed Cascades Involving Acid–Nitrile Exchange

(2014) Laurent El Kaïm et al.   SYNTHESIS-STUTTGART

Iron-Catalyzed Generation of α-Amino Nitriles from Tertiary Amines

(2013) Alexander Wagner et al.   ADVANCED SYNTHESIS & CATALYSIS

Continuous-Flow Oxidative Cyanation of Primary and Secondary Amines Using Singlet Oxygen

(2013) Dmitry B. Ushakov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Mediated Decarboxylation/Oxidative Amidation of α-Keto Acids with Amines under Mild Reaction Conditions Using O2

(2013) Jie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The chemistry of amine radical cations produced by visible light photoredox catalysis

(2013) Jie Hu et al.   Beilstein Journal of Organic Chemistry

A room temperature decarboxylation/C–H functionalization cascade by visible-light photoredox catalysis

(2013) Jin Xie et al.   CHEMICAL COMMUNICATIONS

Visible light-mediated oxidative decarboxylation of arylacetic acids into benzyl radicals: addition to electron-deficient alkenes by using photoredox catalysts

(2013) Yoshihiro Miyake et al.   CHEMICAL COMMUNICATIONS

Room temperature decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids by photoredox catalysis

(2013) Pan Xu et al.   CHEMICAL COMMUNICATIONS

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

One-Pot Transformation of Carboxylic Acids into Nitriles

(2013) Kotaro Miyagi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct Preparation of Nitriles from Carboxylic Acids in Continuous Flow

(2013) David Cantillo et al.   JOURNAL OF ORGANIC CHEMISTRY

A Highly Chemoselective and Practical Alkynylation of Thiols

(2013) Reto Frei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Directed C–H Cyanation of Arenes with N-Cyano-N-phenyl-p-toluenesulfonamide

(2013) Tian-Jun Gong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amphiphilic methyleneamino synthon through organic dye catalyzed-decarboxylative aminoalkylation

(2013) Li Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cobalt-Catalyzed Oxidative α-Cyanation of Tertiary Aromatic Amines with Trimethylsilyl Cyanide and tert-Butyl Hydroperoxide

(2013) Norio Sakai et al.   SYNLETT

Photoinduced Direct Cyanation of C(sp3)-H Bonds

(2013) Masayuki Inoue et al.   SYNTHESIS-STUTTGART

Synthesis of Aromatic Nitriles Using Nonmetallic Cyano-Group Sources

(2012) Jinho Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light Photoredox Catalysis

(2012) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Lepadiformine Alkaloids using N-Boc α-Amino Nitriles as Trianion Synthons

(2012) Matthew A. Perry et al.   JOURNAL OF ORGANIC CHEMISTRY

Friedel–Crafts Amidoalkylation via Thermolysis and Oxidative Photocatalysis

(2012) Chunhui Dai et al.   JOURNAL OF ORGANIC CHEMISTRY

Shining Light on Photoredox Catalysis: Theory and Synthetic Applications

(2012) Joseph W. Tucker et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Catalyzed Decarboxylative Alkynylation of Aliphatic Carboxylic Acids in Aqueous Solution

(2012) Xuesong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-Neutral α-Cyanation of Amines

(2012) Longle Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-light photoredox catalyzed oxidative Strecker reaction

(2011) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

A Density Dependent Dispersion Correction

(2011) Stephan N. Steinmann et al.   CHIMIA

A generalized-gradient approximation exchange hole model for dispersion coefficients

(2011) Stephan N. Steinmann et al.   JOURNAL OF CHEMICAL PHYSICS

Comprehensive Benchmarking of a Density-Dependent Dispersion Correction

(2011) Stephan N. Steinmann et al.   Journal of Chemical Theory and Computation

Photochemically Induced Radical Transformation of C(sp3)–H Bonds to C(sp3)–CN Bonds

(2011) Shin Kamijo et al.   ORGANIC LETTERS

Gold-complexes catalyzed oxidative α-cyanation of tertiary amines

(2010) Yan Zhang et al.   CHEMICAL COMMUNICATIONS

Visible light photoredox catalysis: applications in organic synthesis

(2010) Jagan M. R. Narayanam et al.   CHEMICAL SOCIETY REVIEWS

A System-Dependent Density-Based Dispersion Correction

(2010) Stephan N. Steinmann et al.   Journal of Chemical Theory and Computation

Integration Grid Errors for Meta-GGA-Predicted Reaction Energies: Origin of Grid Errors for the M06 Suite of Functionals

(2010) Steven E. Wheeler et al.   Journal of Chemical Theory and Computation

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visible light photocatalysis as a greener approach to photochemical synthesis

(2010) Tehshik P. Yoon et al.   Nature Chemistry

Iron catalyzed oxidative cyanation of tertiary amines

(2009) Wei Han et al.   CHEMICAL COMMUNICATIONS

An efficient aerobic oxidative cyanation of tertiary amines with sodium cyanide using vanadium based systems as catalysts

(2009) Sweety Singhal et al.   CHEMICAL COMMUNICATIONS

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

(2008) Jacques Yves Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ruthenium-Catalyzed Oxidative Cyanation of Tertiary Amines with Molecular Oxygen or Hydrogen Peroxide and Sodium Cyanide: sp3C−H Bond Activation and Carbon−Carbon Bond Formation

(2008) Shun-Ichi Murahashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Oxidative Cyanation Based on the Concept of Site Isolation

(2008) Toshiki Tajima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE