Synthesis and Biological Evaluation of a Series of Novel Celastrol Derivatives with Amino Acid Chain

Novel celastrol derivatives with improved selectivity and enhanced antitumour activity: Design, synthesis and biological evaluation

(2017) Sandra A.C. Figueiredo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of novel C-29 carbamate celastrol derivatives as potent and selective cytotoxic compounds

(2017) Sandra A.C. Figueiredo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and characterisation of celastrol derivatives as potential anticancer agents

(2017) Hong-Jian Zhang et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Celastrol enhances Nrf2 mediated antioxidant enzymes and exhibits anti-fibrotic effect through regulation of collagen production against bleomycin-induced pulmonary fibrosis

(2016) Thomas Divya et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Treatment of Obesity with Celastrol

(2015) Junli Liu et al.   CELL

Design and synthesis of celastrol derivatives as anticancer agents

(2015) Wen-Jian Tang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The effect of celastrol, a triterpene with antitumorigenic activity, on conformational and functional aspects of the human 90kDa heat shock protein Hsp90α, a chaperone implicated in the stabilization of the tumor phenotype

(2014) Letícia M. Zanphorlin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of Autophagy Strengthens Celastrol-Induced Apoptosis in Human Pancreatic Cancer In Vitro and In Vivo Models

(2014) X. Zhao et al.   CURRENT MOLECULAR MEDICINE

Tirucallane-Type Triterpenoids fromCelastrus stylosusWall.

(2014) Wei-Guang Shan et al.   HELVETICA CHIMICA ACTA

Combination of Amino Acid/Dipeptide with Nitric Oxide Donating Oleanolic Acid Derivatives as PepT1 Targeting Antitumor Prodrugs

(2014) Lei Fang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis and Biological Evaluation of C(6)-Modified Celastrol Derivatives as Potential Antitumor Agents

(2014) Kaiyong Tang et al.   MOLECULES

Celastrol Blocks Interleukin-6 Gene Expression via Downregulation of NF-κB in Prostate Carcinoma Cells

(2014) Kun-Chun Chiang et al.   PLoS One

Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo

(2013) Hong-Lei Jiang et al.   MOLECULAR BIOLOGY REPORTS

Celastrol Analogues as Inducers of the Heat Shock Response. Design and Synthesis of Affinity Probes for the Identification of Protein Targets

(2012) Lada Klaić et al.   ACS Chemical Biology

Synthesis and Biological Evaluation of New Amino Acid and Dipeptide Derivatives of Neocryptolepine as Anticancer Agents

(2012) Katarzyna Sidoryk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappa B signaling pathway in vitro

(2012) Xiao-Nan Wang et al.   Chinese Journal of Cancer

Synthesis and preliminary evaluation of neuroprotection of celastrol analogues in PC12 cells

(2010) Hongli Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer

(2010) Radhamani Kannaiyan et al.   CANCER LETTERS

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

(2010) Sibylle Endter et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

(2008) T. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting

(2007) Fujun Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES