The recognition of glycans by protein receptors. Insights from NMR spectroscopy

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation

(2018) Rebekka Wild et al.   SCIENCE

NMR line shape analysis of a multi-state ligand binding mechanism in chitosanase

(2017) Shoko Shinya et al.   JOURNAL OF BIOMOLECULAR NMR

Direct Observation of Carbohydrate Hydroxyl Protons in Hydrogen Bonds with a Protein

(2017) Gustav Nestor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploiting Uniformly 13C-Labeled Carbohydrates for Probing Carbohydrate–Protein Interactions by NMR Spectroscopy

(2017) Gustav Nestor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

(2017) Abhay Kotecha et al.   Nature Communications

Functional Analysis of Glycosylation of Zika Virus Envelope Protein

(2017) Camila R. Fontes-Garfias et al.   Cell Reports

Strategies for carbohydrate model building, refinement and validation

(2017) Jon Agirre   Acta Crystallographica Section D-Structural Biology

X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer

(2017) Harry B. Gristick et al.   Acta Crystallographica Section D-Structural Biology

Conformational effects of N-glycan core fucosylation of immunoglobulin G Fc region on its interaction with Fcγ receptor IIIa

(2017) Yoshitake Sakae et al.   Scientific Reports

19F NMR-Guided Design of Glycomimetic Langerin Ligands

(2016) Eike-Christian Wamhoff et al.   ACS Chemical Biology

Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations

(2016) Luca Unione et al.   ACS Chemical Biology

Structural Aspects of Heparan Sulfate Binding to Robo1–Ig1–2

(2016) Qi Gao et al.   ACS Chemical Biology

Galectin-3 binds highly galactosylated IgG1 and is crucial for the IgG1 complex mediated inhibition of C5aReceptor induced immune responses

(2016) Kerstin A. Heyl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Current Revolution in Cryo-EM

(2016) Edward H. Egelman   BIOPHYSICAL JOURNAL

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

(2016) Guillaume B.E. Stewart-Jones et al.   CELL

Regulation of antibody effector functions through IgG Fc N-glycosylation

(2016) Isaak Quast et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Organizing multivalency in carbohydrate recognition

(2016) Christian Müller et al.   CHEMICAL SOCIETY REVIEWS

N-glycans of growth factor receptors: their role in receptor function and disease implications

(2016) M. Takahashi et al.   CLINICAL SCIENCE

Isotope-labeling strategies for solution NMR studies of macromolecular assemblies

(2016) Heyi Zhang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A

(2016) Christoffer Hamark et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disease-associated glycans on cell surface proteins

(2016) Motoko Takahashi et al.   MOLECULAR ASPECTS OF MEDICINE

Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8

(2016) Johannes M. Pröpster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop

(2016) Haoqing Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

(2016) J. H. Lee et al.   SCIENCE

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

“Rules of Engagement” of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling

(2016) Roberta Marchetti et al.   ChemistryOpen

Attachment of Norovirus to Histo Blood Group Antigens: A Cooperative Multistep Process

(2015) Alvaro Mallagaray et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Recognition in Chemical and Biological Systems

(2015) Elke Persch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural elucidation of an asparagine-linked oligosaccharide from the hyperthermophilic archaeon, Archaeoglobus fulgidus

(2015) Daisuke Fujinami et al.   CARBOHYDRATE RESEARCH

A Hybrid Strategy for the Preparation of 13C-labeled High-mannose-type Oligosaccharides with Terminal Glucosylation for NMR Study

(2015) Tong Zhu et al.   CHEMISTRY LETTERS

Monitoring Glycan-Protein Interactions by NMR Spectroscopic Analysis: A Simple Chemical Tag That Mimics Natural CH-π Interactions

(2015) Luis P. Calle et al.   CHEMISTRY-A EUROPEAN JOURNAL

Methyl-specific isotopic labeling: a molecular tool box for solution NMR studies of large proteins

(2015) Rime Kerfah et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Paramagnetic NMR probes for characterization of the dynamic conformations and interactions of oligosaccharides

(2015) Koichi Kato et al.   GLYCOCONJUGATE JOURNAL

Langerin–Heparin Interaction: Two Binding Sites for Small and Large Ligands As Revealed by a Combination of NMR Spectroscopy and Cross-Linking Mapping Experiments

(2015) Juan C. Muñoz-García et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Erratum: Surfactant protein D suppresses lung cancer progression by downregulation of epidermal growth factor signalling

(2015) Y Hasegawa et al.   ONCOGENE

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intramolecular N-Glycan/Polypeptide Interactions Observed at Multiple N-Glycan Remodeling Steps through [13C,15N]-N-Acetylglucosamine Labeling of Immunoglobulin G1

(2014) Adam W. Barb   BIOCHEMISTRY

Backbone 1H, 13C, and 15N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein

(2014) Hirokazu Yagi et al.   Biomolecular NMR Assignments

Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor-Associated Mucin Glycopeptides by the Human Macrophage Galactose-Type Lectin

(2014) Filipa Marcelo et al.   CHEMISTRY-A EUROPEAN JOURNAL

NMR structure analysis of uniformly 13C-labeled carbohydrates

(2014) Carolina Fontana et al.   JOURNAL OF BIOMOLECULAR NMR

Lanthanide-Chelating Carbohydrate Conjugates Are Useful Tools To Characterize Carbohydrate Conformation in Solution and Sensitive Sensors to Detect Carbohydrate–Protein Interactions

(2014) Ángeles Canales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent strategies targeting HIV glycans in vaccine design

(2014) Satoru Horiya et al.   Nature Chemical Biology

Surfactant protein D suppresses lung cancer progression by downregulation of epidermal growth factor signaling

(2014) Y Hasegawa et al.   ONCOGENE

The Resolution Revolution

(2014) W. Kuhlbrandt   SCIENCE

Breaking Pseudo-Symmetry in Multiantennary Complex N-Glycans Using Lanthanide-Binding Tags and NMR Pseudo-Contact Shifts

(2013) Angeles Canales et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Terminal Spin Labeling of a High-mannose-type Oligosaccharide for Quantitative NMR Analysis of Its Dynamic Conformation

(2013) Takumi Yamaguchi et al.   CHEMISTRY LETTERS

Fluorinated Carbohydrates as Lectin Ligands: Dissecting Glycan-Cyanovirin Interactions by Using19F NMR Spectroscopy

(2013) Elena Matei et al.   CHEMISTRY-A EUROPEAN JOURNAL

The application of paramagnetic lanthanoid ions in NMR spectroscopy on proteins

(2013) Wei-Min Liu et al.   COORDINATION CHEMISTRY REVIEWS

Protein-Carbohydrate Interactions Studied by NMR: From Molecular Recognition to Drug Design

(2013) Maria del Carmen Fernandez-Alonso et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The role of C-type lectin receptors in immune homeostasis

(2013) Huimin Yan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular Recognition of Complex-Type Biantennary N-Glycans by Protein Receptors: a Three-Dimensional View on Epitope Selection by NMR

(2013) Ana Ardá et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

(2013) D. Lyumkis et al.   SCIENCE

Carbohydrate–Aromatic Interactions

(2012) Juan Luis Asensio et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sialyl Lewisx: A “Pre-Organized Water Oligomer”?

(2012) Florian P. C. Binder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NMR Characterization of Immunoglobulin G Fc Glycan Motion on Enzymatic Sialylation

(2012) Adam W. Barb et al.   BIOCHEMISTRY

Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

(2012) Sayoko Yamamoto et al.   CHEMICAL COMMUNICATIONS

Multivalent glycoconjugates as anti-pathogenic agents

(2012) Anna Bernardi et al.   CHEMICAL SOCIETY REVIEWS

Fluorinated Carbohydrates as Lectin Ligands: Biorelevant Sensors with Capacity to Monitor Anomer Affinity in 19F-NMR-Based Inhibitor Screening

(2012) Sabine André et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

(2012) Gabriel A. Rabinovich et al.   IMMUNITY

Application of Paramagnetic NMR-Validated Molecular Dynamics Simulation to the Analysis of a Conformational Ensemble of a Branched Oligosaccharide

(2012) Ying Zhang et al.   MOLECULES

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Glycosaminoglycans Are Interactants of Langerin: Comparison with gp120 Highlights an Unexpected Calcium-Independent Binding Mode

(2012) Eric Chabrol et al.   PLoS One

Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy

(2012) Adam W. Barb et al.   PROTEIN SCIENCE

Regulation of B Cell Functions by the Sialic Acid-Binding Receptors Siglec-G and CD22

(2012) Julia Jellusova et al.   Frontiers in Immunology

Modifications of Glycans: Biological Significance and Therapeutic Opportunities

(2011) Saddam M. Muthana et al.   ACS Chemical Biology

Carbohydrate-Protein Interactions: A 3D View by NMR

(2011) Virginia Roldós et al.   CHEMBIOCHEM

Paramagnetic Lanthanide Tagging for NMR Conformational Analyses of N-Linked Oligosaccharides

(2011) Sayoko Yamamoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Overexpression of a homogeneous oligosaccharide with 13C labeling by genetically engineered yeast strain

(2011) Yukiko Kamiya et al.   JOURNAL OF BIOMOLECULAR NMR

NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic

(2011) Adam W Barb et al.   Nature Chemical Biology

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable-isotope-assisted NMR approaches to glycoproteins using immunoglobulin G as a model system

(2010) Koichi Kato et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Nuclear Magnetic Resonance Structural Characterization of Substrates Bound to the α-2,6-Sialyltransferase, ST6Gal-I

(2009) Shan Liu et al.   BIOCHEMISTRY

Assessing Carbohydrate-Carbohydrate Interactions by NMR Spectroscopy: The Trisaccharide Epitope from the Marine SpongeMicrociona prolifera

(2009) J. Ignacio Santos et al.   CHEMBIOCHEM

Fluorinated Carbohydrates as Lectin Ligands: Versatile Sensors in19F-Detected Saturation Transfer Difference NMR Spectroscopy

(2009) Tammo Diercks et al.   CHEMISTRY-A EUROPEAN JOURNAL

Expression systems for therapeutic glycoprotein production

(2009) Yves Durocher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

Recent advances in segmental isotope labeling of proteins: NMR applications to large proteins and glycoproteins

(2009) Lenka Skrisovska et al.   JOURNAL OF BIOMOLECULAR NMR

Saturation Transfer Difference (STD) NMR Spectroscopy Characterization of Dual Binding Mode of a Mannose Disaccharide to DC-SIGN

(2008) Jesús Angulo et al.   CHEMBIOCHEM

13C-Sialic Acid Labeling of Glycans on Glycoproteins Using ST6Gal-I

(2008) Megan A. Macnaughtan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure determination of a Galectin-3-carbohydrate complex using paramagnetism-based NMR constraints

(2008) Tiandi Zhuang et al.   PROTEIN SCIENCE

Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands

(2002) Nitin U. Jain et al.   PROTEIN SCIENCE