“Rules of Engagement” of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling

Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis

(2015) Roberta Marchetti et al.   ACS Chemical Biology

Posttranslational Modifications of Intact Proteins Detected by NMR Spectroscopy: Application to Glycosylation

(2015) Mario Schubert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy

(2015) Jan-Henrik Ardenkjaer-Larsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deciphering the Non-Equivalence of Serine and ThreonineO-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

(2015) Nuria Martínez-Sáez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Defining the Interaction of Human Soluble Lectin ZG16p and Mycobacterial Phosphatidylinositol Mannosides

(2015) Shinya Hanashima et al.   CHEMBIOCHEM

A Murine Monoclonal Antibody to Glycogen: Characterization of Epitope-Fine Specificity by Saturation Transfer Difference (STD) NMR Spectroscopy and Its Use in Mycobacterial Capsular α-Glucan Research

(2015) Robert van de Weerd et al.   CHEMBIOCHEM

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Methyl groups as NMR probes for biomolecular interactions

(2015) Silke Wiesner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Algal lectin binding to core (α1–6) fucosylated N-glycans: Structural basis for specificity and production of recombinant protein

(2015) Antônia S F do Nascimento et al.   GLYCOBIOLOGY

Paramagnetic Ligand Tagging To Identify Protein Binding Sites

(2015) Ulrika Brath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR

(2015) Helena Coelho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Langerin–Heparin Interaction: Two Binding Sites for Small and Large Ligands As Revealed by a Combination of NMR Spectroscopy and Cross-Linking Mapping Experiments

(2015) Juan C. Muñoz-García et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbohydrate–Aromatic Interactions in Proteins

(2015) Kieran L. Hudson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Structural Role of Antibody N-Glycosylation in Receptor Interactions

(2015) Ganesh P. Subedi et al.   STRUCTURE

Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

(2014) Felix Broecker et al.   ACS Chemical Biology

Multiple Paramagnetic Effects through a Tagged Reporter Protein

(2014) Aldo R. Camacho-Zarco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Characterization of the DC-SIGN–LewisX Complex

(2014) Kari Pederson et al.   BIOCHEMISTRY

Intramolecular N-Glycan/Polypeptide Interactions Observed at Multiple N-Glycan Remodeling Steps through [13C,15N]-N-Acetylglucosamine Labeling of Immunoglobulin G1

(2014) Adam W. Barb   BIOCHEMISTRY

Recent advances in employing molecular modelling to determine the specificity of glycan-binding proteins

(2014) Oliver C Grant et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

NMR-based Structural Analysis of the Complete Rough-type Lipopolysaccharide Isolated fromCapnocytophaga canimorsus

(2014) Ulrich Zähringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding energy calculations for hevein–carbohydrate interactions using expanded ensemble molecular dynamics simulations

(2014) Chaitanya A. K. Koppisetty et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Study of the Structural and Dynamic Effects in the FimH Adhesin upon α-d-Heptyl Mannose Binding

(2014) Sophie Vanwetswinkel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lanthanide-Chelating Carbohydrate Conjugates Are Useful Tools To Characterize Carbohydrate Conformation in Solution and Sensitive Sensors to Detect Carbohydrate–Protein Interactions

(2014) Ángeles Canales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for sialic acid–mediated self-recognition by complement factor H

(2014) Bärbel S Blaum et al.   Nature Chemical Biology

Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization

(2014) M. Hayafune et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breaking Pseudo-Symmetry in Multiantennary Complex N-Glycans Using Lanthanide-Binding Tags and NMR Pseudo-Contact Shifts

(2013) Angeles Canales et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unraveling the Interaction between the LPS O-Antigen ofBurkholderia anthinaand the 5D8 Monoclonal Antibody by Using a Multidisciplinary Chemical Approach, with Synthesis, NMR, and Molecular Modeling Methods

(2013) Roberta Marchetti et al.   CHEMBIOCHEM

Terminal Spin Labeling of a High-mannose-type Oligosaccharide for Quantitative NMR Analysis of Its Dynamic Conformation

(2013) Takumi Yamaguchi et al.   CHEMISTRY LETTERS

Fluorinated Carbohydrates as Lectin Ligands: Dissecting Glycan-Cyanovirin Interactions by Using19F NMR Spectroscopy

(2013) Elena Matei et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure determination of protein–protein complexes with long-range anisotropic paramagnetic NMR restraints

(2013) Mathias AS Hass et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

NMR study of short β(1-3)-glucans provides insights into the structure and interaction with Dectin-1

(2013) Shinya Hanashima et al.   GLYCOCONJUGATE JOURNAL

Expression and structural characterization of anti-T-antigen single-chain antibodies (scFvs) and analysis of their binding to T-antigen by surface plasmon resonance and NMR spectroscopy

(2013) N. Yuasa et al.   JOURNAL OF BIOCHEMISTRY

Solution NMR Analyses of the C-type Carbohydrate Recognition Domain of DC-SIGNR Protein Reveal Different Binding Modes for HIV-derived Oligosaccharides and Smaller Glycan Fragments

(2013) Fay Probert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilization of Branched Oligosaccharides: Lewisx Benefits from a Nonconventional C–H···O Hydrogen Bond

(2013) Mirko Zierke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-Molecule Binding Sites on Proteins Established by Paramagnetic NMR Spectroscopy

(2013) Jia-Ying Guan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-type Lectin DC-SIGN. Structural Requirements for Selectivity and Ligand Design

(2013) Michel Thépaut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

(2013) Marie Pancera et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Noncarbohydrate Glycomimetics and Glycoprotein Surrogates as DC-SIGN Antagonists and Agonists

(2012) Lynne R. Prost et al.   ACS Chemical Biology

Towards a Structural Basis for the Relationship Between Blood Group and the Severity of El Tor Cholera

(2012) Pintu K. Mandal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NMR Characterization of Immunoglobulin G Fc Glycan Motion on Enzymatic Sialylation

(2012) Adam W. Barb et al.   BIOCHEMISTRY

Synthesis of β(1,3) oligoglucans exhibiting a Dectin-1 binding affinity and their biological evaluation

(2012) Hiroshi Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure of the lipopolysaccharide isolated from the novel species Uruburuella suis

(2012) Alba Silipo et al.   CARBOHYDRATE RESEARCH

Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

(2012) Sayoko Yamamoto et al.   CHEMICAL COMMUNICATIONS

NMR Spectroscopic Analysis Reveals Extensive Binding Interactions of Complex Xyloglucan Oligosaccharides with theCellvibrio japonicusGlycoside Hydrolase Family 31 α-Xylosidase

(2012) Alba Silipo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structural Study of Binding of α-Mannosides to Mannan-Binding Lectins

(2012) Roberta Marchetti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Shigella flexneriO-antigens revisited: final elucidation of the O-acetylation profiles and a survey of the O-antigen structure diversity

(2012) Andrei V. Perepelov et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

(2012) Liping Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent developments and applications of saturation transfer difference nuclear magnetic resonance (STD NMR) spectroscopy

(2012) Jane L. Wagstaff et al.   Molecular BioSystems

Application of Paramagnetic NMR-Validated Molecular Dynamics Simulation to the Analysis of a Conformational Ensemble of a Branched Oligosaccharide

(2012) Ying Zhang et al.   MOLECULES

Characterization of Influenza Hemagglutinin Interactions with Receptor by NMR

(2012) Christopher McCullough et al.   PLoS One

Glycosaminoglycans Are Interactants of Langerin: Comparison with gp120 Highlights an Unexpected Calcium-Independent Binding Mode

(2012) Eric Chabrol et al.   PLoS One

Bacterial Lipopolysaccharides in Plant and Mammalian Innate Immunity

(2012) Cristina De Castro et al.   PROTEIN AND PEPTIDE LETTERS

Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

(2012) Mario Schubert et al.   PLoS Pathogens

Molecular Details of the Recognition of Blood Group Antigens by a Human Norovirus as Determined by STD NMR Spectroscopy

(2011) Brigitte Fiege et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing β-(1→3)-d-glucans interactions with recombinant human receptors using high-resolution NMR studies

(2011) Balla Sylla et al.   CARBOHYDRATE RESEARCH

Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells

(2011) Mihai Ciobanu et al.   CHEMICAL COMMUNICATIONS

A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

(2011) Alvaro Mallagaray et al.   CHEMICAL COMMUNICATIONS

A Solution NMR Study of the Interactions of Oligomannosides and the Anti-HIV-1 2G12 Antibody Reveals Distinct Binding Modes for Branched Ligands*

(2011) Pedro M. Enríquez-Navas et al.   CHEMISTRY-A EUROPEAN JOURNAL

Saturation Transfer Difference NMR Experiments of Membrane Proteins in Living Cells under HR-MAS Conditions: The Interaction of the SGLT1 Co-transporter with Its Ligands

(2011) Cristina Airoldi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Conformational Selection of the AGA*IAM Heparin Pentasaccharide when Bound to the Fibroblast Growth Factor Receptor

(2011) Lidia Nieto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dynamics of the Glycosidic Bond: Conformational Space of Lactose

(2011) Máté Erdélyi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Investigation of the Binding of a Carbohydrate-Mimetic Peptide to its Complementary Anticarbohydrate Antibody by STD-NMR Spectroscopy and Molecular-Dynamics Simulations

(2011) Monica G. Szczepina et al.   CHEMISTRY-A EUROPEAN JOURNAL

Paramagnetic Lanthanide Tagging for NMR Conformational Analyses of N-Linked Oligosaccharides

(2011) Sayoko Yamamoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

WaterLOGSY NMR Experiments in Conjunction with Molecular-Dynamics Simulations Identify Immobilized Water Molecules That Bridge Peptide Mimic MDWNMHAA to Anticarbohydrate Antibody SYA/J6

(2011) Monica G. Szczepina et al.   CHEMISTRY-A EUROPEAN JOURNAL

Targeting Norovirus Infection-Multivalent Entry Inhibitor Design Based on NMR Experiments

(2011) Christoph Rademacher et al.   CHEMISTRY-A EUROPEAN JOURNAL

STD-NMR: application to transient interactions between biomolecules—a quantitative approach

(2011) Jesus Angulo et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Structural aspects of binding of α-linked digalactosides to human galectin-1

(2011) Michelle C Miller et al.   GLYCOBIOLOGY

Structural Flexibility of the Macrophage Dengue Virus Receptor CLEC5A

(2011) Aleksandra A. Watson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Insights into molecular recognition of LewisX mimics by DC-SIGN using NMR and molecular modelling

(2011) Cinzia Guzzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and binding analysis of unique AG2 pentasaccharide to human Siglec-2 using NMR techniques

(2010) Shinya Hanashima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ligand-Receptor Binding Affinities from Saturation Transfer Difference (STD) NMR Spectroscopy: The Binding Isotherm of STD Initial Growth Rates

(2010) Jesús Angulo et al.   CHEMISTRY-A EUROPEAN JOURNAL

PCS-based structure determination of protein–protein complexes

(2010) Tomohide Saio et al.   JOURNAL OF BIOMOLECULAR NMR

Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency

(2010) Christopher W. Murray et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human RegIV Protein Adopts a Typical C-Type Lectin Fold but Binds Mannan with Two Calcium-Independent Sites

(2010) Meng-Ru Ho et al.   JOURNAL OF MOLECULAR BIOLOGY

Presentation of Membrane-Anchored Glycosphingolipids Determined from Molecular Dynamics Simulations and NMR Paramagnetic Relaxation Rate Enhancement

(2010) Mari L. DeMarco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Analysis of Carbohydrate−Antibody Interactions: Case Study Using aBacillus anthracisTetrasaccharide

(2010) Matthias A. Oberli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clean STD-NMR spectrum for improved detection of ligand-protein interactions at low concentration of protein

(2010) Youlin Xia et al.   MAGNETIC RESONANCE IN CHEMISTRY

STD-NMR Studies Suggest that Two Acceptor Substrates for GlfT2, a Bifunctional Galactofuranosyltransferase Required for the Biosynthesis ofMycobacterium tuberculosisArabinogalactan, Compete for the Same Binding Site

(2009) Monica G. Szczepina et al.   CHEMBIOCHEM

Fluorinated Carbohydrates as Lectin Ligands: Versatile Sensors in19F-Detected Saturation Transfer Difference NMR Spectroscopy

(2009) Tammo Diercks et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ligand based NMR methods for drug discovery

(2009) Christian Ludwig   Frontiers in Bioscience-Landmark

Molecular Phenotyping of Mannosyltransferases-Deficient Candida albicans Cells by High-Resolution Magic Angle Spinning NMR

(2009) Emmanuel Maes et al.   JOURNAL OF BIOCHEMISTRY

Selective backbone labelling of ILV methyl labelled proteins

(2009) Nathalie Sibille et al.   JOURNAL OF BIOMOLECULAR NMR

Avian Influenza H5-Containing Virus-Like Particles (VLPs): Host-Cell Receptor Specificity by STD NMR Spectroscopy

(2008) Thomas Haselhorst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Saturation Transfer Difference (STD) NMR Spectroscopy Characterization of Dual Binding Mode of a Mannose Disaccharide to DC-SIGN

(2008) Jesús Angulo et al.   CHEMBIOCHEM

Microbial recognition of human cell surface glycoconjugates

(2008) Anne Imberty et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

(2008) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Competition Saturation Transfer Difference Experiments Improved with Isotope Editing and Filtering Schemes in NMR-Based Screening

(2008) Krisztina Fehér et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation of Binding of UDP-Galfand UDP-[3-F]Galfto UDP-galactopyranose Mutase by STD-NMR Spectroscopy, Molecular Dynamics, and CORCEMA-ST Calculations†

(2008) Yue Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Experiments Reveal the Molecular Basis of Receptor Recognition by a Calicivirus

(2008) Christoph Rademacher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin

(2008) José J. Reina et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

(2008) S.-K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure determination of a Galectin-3-carbohydrate complex using paramagnetism-based NMR constraints

(2008) Tiandi Zhuang et al.   PROTEIN SCIENCE

Structure and Function of the Cell Surface (Tethered) Mucins

(2007) Christine L. Hattrup et al.   Annual Review of Physiology

SALMON: Solvent Accessibility, Ligand binding, and Mapping of ligand Orientation by NMR Spectroscopy

(2007) Christian Ludwig et al.   JOURNAL OF MEDICINAL CHEMISTRY

Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands

(2002) Nitin U. Jain et al.   PROTEIN SCIENCE