In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB

Overcoming β-lactam resistance in Gram-negative pathogens

(2016) Karen Bush   Future Medicinal Chemistry

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Design, synthesis and characterization of new 1,2,3-triazolyl pyrazole derivatives as potential antimicrobial agents via a Vilsmeier–Haack reaction approach

(2016) Manjunatha Bhat et al.   RSC Advances

Synthesis and in vitro kinetic study of novel mono-pyridinium oximes as reactivators of organophosphorus (OP) inhibited human acetylcholinesterase (hAChE)

(2015) Aditya Kapil Valiveti et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F

(2014) Martina Hrast et al.   BIOORGANIC CHEMISTRY

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Correction: Association of pol Diversity with Antiretroviral Treatment Outcomes among HIV-Infected African Children

(2013) Iris Chen et al.   PLoS One

Bacterial cell wall assembly: still an attractive antibacterial target

(2011) Timothy D.H. Bugg et al.   TRENDS IN BIOTECHNOLOGY

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Pharmacophore Based Drug Design Approach as a Practical Process in Drug Discovery

(2010) Qingzhi Gao et al.   Current Computer-Aided Drug Design

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Validation of Molecular Docking Programs for Virtual Screening against Dihydropteroate Synthase

(2009) Kirk E. Hevener et al.   Journal of Chemical Information and Modeling