An emerging link between LIM domain proteins and nuclear receptors

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations

(2017) Stefano Sala et al.   JOURNAL OF PROTEOME RESEARCH

Actin, actin-binding proteins, and actin-related proteins in the nucleus

(2016) Ildikó Kristó et al.   HISTOCHEMISTRY AND CELL BIOLOGY

α Actinin 4 (ACTN4) Regulates Glucocorticoid Receptor-mediated Transactivation and Transrepression in Podocytes

(2016) Xuan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Analyses of Zinc Finger Domains for Specific Interactions with DNA

(2016) Ki Seong Eom et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Mutation of orthologouspricklegenes causes a similar epilepsy syndrome in flies and humans

(2016) Salleh N. Ehaideb et al.   Annals of Clinical and Translational Neurology

The LIM protein Ajuba promotes adipogenesis by enhancing PPARγ and p300/CBP interaction

(2015) Q Li et al.   CELL DEATH AND DIFFERENTIATION

Transcription of Nrdp1 by the androgen receptor is regulated by nuclear filamin A in prostate cancer

(2015) R. M. Savoy et al.   ENDOCRINE-RELATED CANCER

Upregulated LMO1 in prostate cancer acts as a novel coactivator of the androgen receptor

(2015) HUI GU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α

(2015) SILKE KAULFUSS et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Selective Coregulator Function and Restriction of Steroid Receptor Chromatin Occupancy by Hic-5

(2015) Rajas Chodankar et al.   MOLECULAR ENDOCRINOLOGY

Ajuba Preferentially Binds LXRα/RXRγ Heterodimer to Enhance LXR Target Gene Expression in Liver Cells

(2015) Hongyan Fan et al.   MOLECULAR ENDOCRINOLOGY

PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm

(2015) Rumiko Ono et al.   Scientific Reports

The actin cytoskeleton in rapid steroid hormone actions

(2014) Christos Stournaras et al.   Cytoskeleton

LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis

(2014) Kondababu Kurakula et al.   MOLECULAR AND CELLULAR BIOLOGY

Hic-5 influences genomic and non-genomic actions of the androgen receptor in prostate myofibroblasts

(2014) Damien A. Leach et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

VDR Activity Is Differentially Affected by Hic-5 in Prostate Cancer and Stromal Cells

(2014) Joshua D. Solomon et al.   MOLECULAR CANCER RESEARCH

Elevated LIM Kinase 1 in Nonmetastatic Prostate Cancer Reflects Its Role in Facilitating Androgen Receptor Nuclear Translocation

(2014) K. Mardilovich et al.   MOLECULAR CANCER THERAPEUTICS

Nuclear receptors in neurodegenerative diseases

(2014) Rebecca Skerrett et al.   NEUROBIOLOGY OF DISEASE

The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters

(2014) Markus E. Diefenbacher et al.   PLoS One

Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner

(2014) R. Chodankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation

(2014) Ales Obrdlik et al.   Nucleus

Nuclear Receptor Coactivators: Master Regulators of Human Health and Disease

(2013) Subhamoy Dasgupta et al.   Annual Review of Medicine

Zyxin cooperates with PTOV1 to confer retinoic acid resistance by repressing RAR activity

(2013) HyeSook Youn et al.   CANCER LETTERS

Regulation of the Transcriptional Coactivator FHL2 Licenses Activation of the Androgen Receptor in Castrate-Resistant Prostate Cancer

(2013) M. J. McGrath et al.   CANCER RESEARCH

The orphan nuclear receptors at their 25-year reunion

(2013) Shannon E Mullican et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Zyxin is a novel target for beta-amyloid peptide: characterization of its role in Alzheimer's pathogenesis

(2013) Cristina Lanni et al.   JOURNAL OF NEUROCHEMISTRY

The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis

(2013) Abdulaleem Alnajar et al.   PLoS One

Signaling by Nuclear Receptors

(2013) R. Sever et al.   Cold Spring Harbor Perspectives in Biology

Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation

(2012) Aritro Sen et al.   JOURNAL OF CLINICAL INVESTIGATION

The LIM Domain Protein FHL2 Interacts with the NR5A Family of Nuclear Receptors and CREB to Activate the Inhibin-α Subunit Gene in Ovarian Granulosa Cells

(2012) Christina K. Matulis et al.   MOLECULAR ENDOCRINOLOGY

A LIM Domain Protein from Tobacco Involved in Actin-Bundling and Histone Gene Transcription

(2012) Danièle Moes et al.   Molecular Plant

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein–protein interactions

(2012) S Mihlan et al.   ONCOGENE

The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development

(2012) Amy Li et al.   PROTEOMICS

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes

(2011) Mohammad Ishaq et al.   BMC MOLECULAR BIOLOGY

Increased Acetylation in the DNA-binding Domain of TR4 Nuclear Receptor by the Coregulator ARA55 Leads to Suppression of TR4 Transactivation

(2011) Shaozhen Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FHL2 Protein Is a Novel Co-repressor of Nuclear Receptor Nur77

(2011) Kondababu Kurakula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma

(2011) C-Y Chang et al.   ONCOGENE

Nuclear receptors as drug targets for metabolic disease

(2010) Ira G. Schulman   ADVANCED DRUG DELIVERY REVIEWS

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

(2010) C.-W. Ni et al.   BLOOD

Synergistic repression of estrogen receptor transcriptional activity by FHL2 and Smad4 in breast cancer cells

(2010) Zhihong Xiong et al.   IUBMB LIFE

Paxillin and Hydrogen Peroxide-Inducible Clone 5 Expression and Distribution in Control and Alzheimer Disease Hippocampi

(2010) John Caltagarone et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor

(2010) Markus E. Diefenbacher et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling

(2010) Z. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

It Takes Two to Tango: The Structure and Function of LIM, RING, PHD and MYND Domains

(2009) J. Matthews et al.   CURRENT PHARMACEUTICAL DESIGN

The Progesterone Receptor Coactivator Hic-5 Is Involved in the Pathophysiology of Endometriosis

(2009) Lusine Aghajanova et al.   ENDOCRINOLOGY

FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth

(2009) Lihua Ding et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4motif: evidence that nuclear paxillin promotes cell proliferation

(2008) Jing-Ming Dong et al.   BIOCHEMICAL JOURNAL

Nuclear receptors and coregulators in inflammation and cancer

(2008) Jason S. Lee et al.   CANCER LETTERS

Sequestration of PDLIM2 in the cytoplasm of monocytic/macrophage cells is associated with adhesion and increased nuclear activity of NF-κB

(2008) Nollaig C. Healy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rescue of Neurons from Ischemic Injury by Peroxisome Proliferator-Activated Receptor-  Requires a Novel Essential Cofactor LMO4

(2008) S. C. Schock et al.   JOURNAL OF NEUROSCIENCE

Leupaxin, a Novel Coactivator of the Androgen Receptor, Is Expressed in Prostate Cancer and Plays a Role in Adhesion and Invasion of Prostate Carcinoma Cells

(2008) Silke Kaulfuss et al.   MOLECULAR ENDOCRINOLOGY