Epigenetic Mechanisms in Inflammation

Age-associated epigenetic modifications in human DNA increase its immunogenicity

(2016) Anshu Agrawal et al.   Aging-US

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

(2014) G. Lal et al.   JOURNAL OF IMMUNOLOGY

The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the Polycomb group protein EZH2 in cancer

(2011) Jeffrey M. Friedman et al.   CELL CYCLE

Coordinated Chromatin Control: Structural and Functional Linkage of DNA and Histone Methylation

(2010) Xiaodong Cheng et al.   BIOCHEMISTRY

Inflammatory Processes Triggered by Helicobacter pylori Infection Cause Aberrant DNA Methylation in Gastric Epithelial Cells

(2010) T. Niwa et al.   CANCER RESEARCH

Helicobacter pyloriinfection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis

(2010) Song-Ze Ding et al.   Future Oncology

Jarid2 and PRC2, partners in regulating gene expression

(2010) G. Li et al.   GENES & DEVELOPMENT

microRNAs in Inflammation

(2010) Enikö Sonkoly et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Epigenetics and autoimmunity

(2010) Wesley H. Brooks et al.   JOURNAL OF AUTOIMMUNITY

MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance

(2010) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetics in atherosclerosis and inflammation

(2010) Rutger J. Wierda et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Transcriptome Remodeling in Hypoxic Inflammation

(2010) O. Safronova et al.   JOURNAL OF DENTAL RESEARCH

Altered gene expression in murine placentas in an infection-induced intrauterine growth restriction model: a microarray analysis

(2010) Y.A. Bobetsis et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency by Virus-Encoded MicroRNAs That Target Rta and the Cellular Rbl2-DNMT Pathway

(2010) F. Lu et al.   JOURNAL OF VIROLOGY

Epigenetic Basis for Fetal Origins of Age-Related Disease

(2010) Reid F. Thompson et al.   JOURNAL OF WOMENS HEALTH

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

(2010) Diego Pasini et al.   NATURE

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators

(2010) David Landeira et al.   NATURE CELL BIOLOGY

Polycomb group protein-mediated repression of transcription

(2010) Lluís Morey et al.   TRENDS IN BIOCHEMICAL SCIENCES

Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications

(2009) Rabab El Mezayen et al.   AGING CELL

Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice

(2009) Jiyeon Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Helicobacter pylori causes runx3 gene methylation and its loss of expression in gastric epithelial cells, which is mediated by nitric oxide produced by macrophages

(2009) Yasumi Katayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA methylation of cancer genome

(2009) Hoi-Hung Cheung et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer

(2009) E K O Ng et al.   BRITISH JOURNAL OF CANCER

Switching on Epigenetic Therapy

(2009) Sascha Karberg   CELL

Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells

(2009) Jamy C. Peng et al.   CELL

Jumonji Modulates Polycomb Activity and Self-Renewal versus Differentiation of Stem Cells

(2009) Xiaohua Shen et al.   CELL

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications

(2009) M. T. McCabe et al.   CLINICAL CANCER RESEARCH

Tyrosine Kinases and Inflammatory Signalling

(2009) Theresa Page et al.   CURRENT MOLECULAR MEDICINE

Current concepts on the role of inflammation in COPD and lung cancer

(2009) Hongwei Yao et al.   CURRENT OPINION IN PHARMACOLOGY

Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer

(2009) Gina Lee et al.   CURRENT OPINION IN PULMONARY MEDICINE

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

Epigenomic targets for the treatment of respiratory disease

(2009) Rayleen V Bowman et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis

(2009) Jelena Mann et al.   GASTROENTEROLOGY

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

Epigenetics and periodontal disease: future perspectives

(2009) Ricardo Santiago Gomez et al.   INFLAMMATION RESEARCH

The NF-κB Factor RelB and Histone H3 Lysine Methyltransferase G9a Directly Interact to Generate Epigenetic Silencing in Endotoxin Tolerance

(2009) Xiaoping Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of TLR2 Protein Expression by miR-105 in Human Oral Keratinocytes

(2009) Manjunatha R. Benakanakere et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

(2009) Zhaoyong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetics: Connecting Environment and Genotype to Phenotype and Disease

(2009) S.P. Barros et al.   JOURNAL OF DENTAL RESEARCH

Alteration of PTGS2 Promoter Methylation in Chronic Periodontitis

(2009) S. Zhang et al.   JOURNAL OF DENTAL RESEARCH

Epigenetic Regulation of TLR4 Gene Expression in Intestinal Epithelial Cells for the Maintenance of Intestinal Homeostasis

(2009) K. Takahashi et al.   JOURNAL OF IMMUNOLOGY

New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting

(2009) A. D. Wells   JOURNAL OF IMMUNOLOGY

Epigenetics, miRNAs, and human cancer: a new chapter in human gene regulation

(2009) Nicola Valeri et al.   MAMMALIAN GENOME

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

(2009) Aster H. Juan et al.   MOLECULAR CELL

Innate immunity, epigenetics and autoimmunity in rheumatoid arthritis

(2009) Hanna Maciejewska Rodrigues et al.   MOLECULAR IMMUNOLOGY

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Rethinking how DNA methylation patterns are maintained

(2009) Peter A. Jones et al.   NATURE REVIEWS GENETICS

In Brief

(2009)   NATURE REVIEWS NEUROSCIENCE

Epigenetic control in rheumatoid arthritis synovial fibroblasts

(2009) Emmanuel Karouzakis et al.   Nature Reviews Rheumatology

The multi-domain protein Np95 connects DNA methylation and histone modification

(2009) Andrea Rottach et al.   NUCLEIC ACIDS RESEARCH

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

(2009) Jesper Worm et al.   NUCLEIC ACIDS RESEARCH

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

(2009) E J Noonan et al.   ONCOGENE

Histone deacetylases and the immunological network: implications in cancer and inflammation

(2009) A Villagra et al.   ONCOGENE

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-terminus of histone H3 is required for de novo DNA methylation in chromatin

(2009) Jia-Lei Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb group complexes – many combinations, many functions

(2009) Tom K. Kerppola   TRENDS IN CELL BIOLOGY

Epigenetic regulation: methylation of histone and non-histone proteins

(2009) Fei Lan et al.   Science in China. Series C, Life sciences / Chinese Academy of Sciences

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

(2008) S. Sander et al.   BLOOD

Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation

(2008) M. A. Hahn et al.   CANCER RESEARCH

MicroRNA-26a Targets the Histone MethyltransferaseEnhancer of Zeste homolog 2during Myogenesis

(2008) Chung Fai Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G9a and HP1 Couple Histone and DNA Methylation to TNFα Transcription Silencing during Endotoxin Tolerance

(2008) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

Epigenetic modifications in rheumatoid arthritis

(2008) Simon Strietholt et al.   ARTHRITIS RESEARCH & THERAPY