Laminopathies: what can humans learn from fruit flies

Invertebrate models of lamin diseases

(2018) Ryszard Rzepecki et al.   Nucleus

Invertebrate models of lamin diseases

(2018) Ryszard Rzepecki et al.   Nucleus

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

The molecular architecture of lamins in somatic cells

(2017) Yagmur Turgay et al.   NATURE

The structure of lamin filaments in somatic cells as revealed by cryo-electron tomography

(2017) Y. Turgay et al.   Nucleus

Evolutionary changes in lamin expression in the vertebrate lineage

(2017) Reimer Stick et al.   Nucleus

The structure of lamin filaments in somatic cells as revealed by cryo-electron tomography

(2017) Y. Turgay et al.   Nucleus

Evolutionary changes in lamin expression in the vertebrate lineage

(2017) Reimer Stick et al.   Nucleus

Cross talk between the cytoplasm and nucleus during development and disease

(2016) Lori L Wallrath et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis inDrosophilamale meiosis

(2016) Daisuke Hayashi et al.   Biology Open

Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

(2015) Yosef Gruenbaum et al.   Annual Review of Biochemistry

A Drosophila Model of Epidermolysis Bullosa Simplex

(2015) Jens Bohnekamp et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Loss of lamin A function increases chromatin dynamics in the nuclear interior

(2015) I. Bronshtein et al.   Nature Communications

Regulation of lamin properties and functions: does phosphorylation do it all?

(2015) Magdalena Machowska et al.   Open Biology

Myopathic Lamin Mutations Cause Reductive Stress and Activate the Nrf2/Keap-1 Pathway

(2015) George Dialynas et al.   PLoS Genetics

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

(2014) Amnon Buxboim et al.   CURRENT BIOLOGY

Lamins of the sea lamprey (Petromyzon marinus) and the evolution of the vertebrate lamin protein family

(2014) Paul Schilf et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Unique and Shared Functions of Nuclear Lamina LEM Domain Proteins in Drosophila

(2014) Lacy J. Barton et al.   GENETICS

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies

(2014) Z.-J. Chen et al.   JOURNAL OF CELL SCIENCE

Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

(2014) Peter Meinke et al.   PLoS Genetics

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Loss of Drosophila A-type lamin C initially causes tendon abnormality including disintegration of cytoskeleton and nuclear lamina in muscular defects

(2012) Ryo Uchino et al.   DEVELOPMENTAL BIOLOGY

Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1

(2012) Jianbin Ruan et al.   FEBS LETTERS

The Different Function of Single Phosphorylation Sites of Drosophila melanogaster Lamin Dm and Lamin C

(2012) Magdalena Zaremba-Czogalla et al.   PLoS One

Evolution of the lamin protein family

(2012) Annette Peter et al.   Nucleus

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle

(2011) E Mattioli et al.   CELL DEATH AND DIFFERENTIATION

LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle

(2011) George Dialynas et al.   HUMAN MOLECULAR GENETICS

Filaments assembly of ectopically expressed Caenorhabditis elegans lamin within Xenopus oocytes

(2011) Einat Grossman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Identification of new in vivo phosphosites on lamin Dm - the evidence of heterogeneity of phosphorylation sites in differentDrosophilatissues

(2011) Magdalena Zaremba-Czogalla et al.   Nucleus

Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes

(2010) Maya Capelson et al.   CELL

The role of Drosophila Lamin C in muscle function and gene expression

(2010) G. Dialynas et al.   DEVELOPMENT

Lamin C and chromatin organization in Drosophila

(2010) B. V. Gurudatta et al.   JOURNAL OF GENETICS

A Comparative Study of Drosophila and Human A-Type Lamins

(2009) Sandra R. Schulze et al.   PLoS One

The B-type lamin is required for somatic repression of testis-specific gene clusters

(2009) Y. Y. Shevelyov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The farnesylated nuclear proteins KUGELKERN and LAMIN B promote aging-like phenotypes inDrosophilaflies

(2008) Annely Brandt et al.   AGING CELL

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT