SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

(2017) Na Li et al.   HEPATOLOGY

Expression of oncogenic miR-17-92 and tumor suppressive miR-143-145 clusters in basal cell carcinoma and cutaneous squamous cell carcinoma

(2017) Michael Sand et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention

(2017) Mohammad Alam Jafri et al.   SEMINARS IN CANCER BIOLOGY

The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth

(2016) Maria Teresa Bengoechea-Alonso et al.   CELL CYCLE

SREBP-1 is an independent prognostic marker and promotes invasion and migration in breast cancer

(2016) Jisheng Bao et al.   Oncology Letters

Breast cancer statistics, 2015: Convergence of incidence rates between black and white women

(2015) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

53BP1suppresses epithelial-mesenchymal transition by downregulatingZEB1through microRNA-200b/429 in breast cancer

(2015) Xiangnan Kong et al.   CANCER SCIENCE

miR-128 represses L1 retrotransposition by binding directly to L1 RNA

(2015) Matthias Hamdorf et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miR-128 represses L1 retrotransposition by binding directly to L1 RNA

(2015) Matthias Hamdorf et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer

(2015) Gloria Bertoli et al.   Theranostics

PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer

(2014) R. Yao et al.   CANCER RESEARCH

SREBP-1 Has a Prognostic Role and Contributes to Invasion and Metastasis in Human Hepatocellular Carcinoma

(2014) Chao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

(2014) Rafaela Ruiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Clinical Significance and Prognostic Value of microRNA Expression Signatures in Hepatocellular Carcinoma

(2013) R. Wei et al.   CLINICAL CANCER RESEARCH

mir-17-92: a polycistronic oncomir with pleiotropic functions

(2013) Virginie Olive et al.   IMMUNOLOGICAL REVIEWS

The Oncogene Metadherin Modulates the Apoptotic Pathway Based on the Tumor Necrosis Factor Superfamily Member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in Breast Cancer

(2013) Ning Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-17-92 Cluster Mediates the Proliferation and Survival of Neural Progenitor Cells after Stroke

(2013) Xian Shuang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-30a suppresses breast tumor growth and metastasis by targeting metadherin

(2013) N Zhang et al.   ONCOGENE

Sterol regulatory element-binding protein 1 is required for ovarian tumor growth

(2013) LONG-YUN NIE et al.   ONCOLOGY REPORTS

Repression of endometrial tumor growth by targeting SREBP1 and lipogenesis

(2012) Weihua Li et al.   CELL CYCLE

Expanding Roles for SREBP in Metabolism

(2012) Wei Shao et al.   Cell Metabolism

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells

(2011) W.-C. Huang et al.   MOLECULAR CANCER RESEARCH

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin

(2011) Z-T Tong et al.   ONCOGENE

An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway

(2011) D. Guo et al.   Cancer Discovery

Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue

(2010) Peng Su et al.   Diagnostic Pathology

mir-17-92, a cluster of miRNAs in the midst of the cancer network

(2010) Virginie Olive et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

(2010) Z. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

(2009) Johannes von Burstin et al.   GASTROENTEROLOGY

miRiad Roles for the miR-17-92 Cluster in Development and Disease

(2008) Joshua T. Mendell   CELL

Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes

(2008) Brian D. Reed et al.   PLoS Genetics