Mechanisms of AMPK in the maintenance of ATP balance during energy metabolism

Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds

(2017) Fabiola Marín-Aguilar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cancer stem cells: The root of tumor recurrence and metastases

(2017) Claudia Peitzsch et al.   SEMINARS IN CANCER BIOLOGY

ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells

(2016) Shanshan Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms

(2016) Y. Qian et al.   MOLECULAR CANCER RESEARCH

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

(2016) Linda S. Steelman et al.   Aging-US

Oxidative stress induces phosphorylation of neuronal NOS in cardiomyocytes through AMP-activated protein kinase (AMPK)

(2015) Rekha Kar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation

(2015) Nicole Witte et al.   ENDOCRINOLOGY

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

AMPK, a metabolic sensor, is involved in isoeugenol-induced glucose uptake in muscle cells

(2015) Nami Kim et al.   JOURNAL OF ENDOCRINOLOGY

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

(2015) Morgan D. Fullerton et al.   JOURNAL OF LIPID RESEARCH

Visfatin, a novel adipokine, stimulates glucose uptake through the Ca2+-dependent AMPK-p38 MAPK pathway in C2C12 skeletal muscle cells

(2015) J. O. Lee et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

ChREBP binding and histone modifications modulate hepatic expression of the Fasn gene in a metabolic syndrome rat model

(2015) Takuji Suzuki et al.   NUTRITION

Response to energy depletion: miR-451/AMPK loop

(2015) Agnieszka Bronisz et al.   Oncotarget

Prognostic Value of Malic Enzyme and ATP-Citrate Lyase in Non-Small Cell Lung Cancer of the Young and the Elderly

(2015) Agnes Csanadi et al.   PLoS One

MLK3 Phophorylates AMPK Independently of LKB1

(2015) Lingyu Luo et al.   PLoS One

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling

(2015) Bingqing Huang et al.   Oncotarget

AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

(2014) Tz-Chuen Ju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells

(2014) Yanrong Qian et al.   CANCER LETTERS

AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice

(2014) Hayley M. O’Neill et al.   DIABETOLOGIA

Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP

(2014) F. Romana Auciello et al.   FEBS LETTERS

Metformin Induces Apoptosis and Cell Cycle Arrest Mediated by Oxidative Stress, AMPK and FOXO3a in MCF-7 Breast Cancer Cells

(2014) Eveline A. I. F. Queiroz et al.   PLoS One

ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells

(2014) Yongjun Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

(2013) Shi-Bei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

LKB1 and AMPK and the cancer-metabolism link - ten years after

(2013) D Hardie et al.   BMC BIOLOGY

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

ATP citrate lyase knockdown impacts cancer stem cells in vitro

(2013) J-i Hanai et al.   Cell Death & Disease

AMPK Enhances Insulin-Stimulated GLUT4 Regulation via Lowering Membrane Cholesterol

(2012) Kirk M. Habegger et al.   ENDOCRINOLOGY

CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin

(2012) Sinju Sundaresan et al.   FASEB JOURNAL

In Vivo, Fatty Acid Translocase (CD36) Critically Regulates Skeletal Muscle Fuel Selection, Exercise Performance, and Training-induced Adaptation of Fatty Acid Oxidation

(2012) Jay T. McFarlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice

(2012) Gado Dramane et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional Regulation of Pyruvate Dehydrogenase Kinase

(2012) Ji Yun Jeong et al.   Diabetes & Metabolism Journal

Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation

(2011) Hakam Alkhateeb et al.   Applied Physiology Nutrition and Metabolism

Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells

(2011) Y. Zhou et al.   CANCER RESEARCH

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells

(2011) A. M. Martelli et al.   CURRENT MEDICINAL CHEMISTRY

CTRP1 Protein Enhances Fatty Acid Oxidation via AMP-activated Protein Kinase (AMPK) Activation and Acetyl-CoA Carboxylase (ACC) Inhibition

(2011) Jonathan M. Peterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein Kinase (MAPK) and Phosphatidylinositol-3-kinase (PI3K)/AKT pathways

(2011) Jun-ichi Hanai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MEF2A Binding to the Glut4 Promoter Occurs via an AMPKα2-Dependent Mechanism

(2011) HAOJIE GONG et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

AMPK -> ULK1 -> Autophagy

(2011) P. J. Roach   MOLECULAR AND CELLULAR BIOLOGY

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of HMG-CoA reductase in mammals and yeast

(2011) John S. Burg et al.   PROGRESS IN LIPID RESEARCH

Extracellular ATP reduces tumor sphere growth and cancer stem cell population in glioblastoma cells

(2011) Pítia Flores Ledur et al.   Purinergic Signalling

The androgen derivative 5α-androstane-3β,17β-diol inhibits tumor necrosis factor α and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta

(2010) Giuseppe Danilo Norata et al.   ATHEROSCLEROSIS

Extracellular ATP enhances in vitro invasion of prostate cancer cells by activating Rho GTPase and upregulating MMPs expression

(2010) Yang Zhang et al.   CANCER LETTERS

Identification of the Citrate-binding Site of Human ATP-Citrate Lyase Using X-ray Crystallography

(2010) Tianjun Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria

(2010) Katia Aquilano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

(2010) Jan F. C. Glatz et al.   PHYSIOLOGICAL REVIEWS

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

(2009) S. Hoppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

Transcriptional activation of hypoxia-inducible factor-1α by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

(2008) Hee-Won Seo et al.   FEBS LETTERS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

SNF1/AMPK pathways in yeast

(2007) Kristina Hedbacker   Frontiers in Bioscience-Landmark