Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling

(2014) John W. Scott et al.   CHEMISTRY & BIOLOGY

Akt Inhibition Promotes ABCA1-Mediated Cholesterol Efflux to ApoA-I through Suppressing mTORC1

(2014) Fumin Dong et al.   PLoS One

Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development

(2013) Akifumi Kushiyama et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol Efflux Capacity

(2013) Amit V. Khera et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

5′-AMP–Activated Protein Kinase–Activating Transcription Factor 1 Cascade Modulates Human Monocyte–Derived Macrophages to Atheroprotective Functions in Response to Heme or Metformin

(2013) Xinyi Wan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammation and immune system interactions in atherosclerosis

(2013) Bart Legein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation

(2013) Chunsheng Dong et al.   GENE

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Is it time to revise the HDL cholesterol hypothesis?

(2012) Daniel J Rader et al.   NATURE MEDICINE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Targeting High Density Lipoproteins in the Prevention of Cardiovascular Disease?

(2012) Daniel B. Larach et al.   Current Cardiology Reports

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

(2011) Sandra Galic et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Adenosine Monophosphate Activated Protein Kinase Regulates ABCG1-Mediated Oxysterol Efflux From Endothelial Cells and Protects Against Hypercholesterolemia-Induced Endothelial Dysfunction

(2010) Dan Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adenosine Monophosphate-activated Protein Kinase Induces Cholesterol Efflux from Macrophage-derived Foam Cells and Alleviates Atherosclerosis in Apolipoprotein E-deficient Mice

(2010) Dan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Accessory to the ‘Trinity’: SR-As Are Essential Pathogen Sensors of Extracellular dsRNA, Mediating Entry and Leading to Subsequent Type I IFN Responses

(2010) Stephanie J. DeWitte-Orr et al.   PLoS Pathogens

Rationale and design of the dal-OUTCOMES trial: Efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome

(2009) Gregory G. Schwartz et al.   AMERICAN HEART JOURNAL

Germline deletion of AMP-activated protein kinase β subunits reduces bone mass without altering osteoclast differentiation or function

(2009) Julian M. W. Quinn et al.   FASEB JOURNAL

Interleukin-10 Facilitates Both Cholesterol Uptake and Efflux in Macrophages

(2009) Xinbing Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance

(2009) Nicolas Dzamko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Macrophage cholesteryl ester mobilization and atherosclerosis

(2009) Shobha Ghosh et al.   VASCULAR PHARMACOLOGY

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

(2008) Daniel J. Rader et al.   JOURNAL OF LIPID RESEARCH

Coexistence of Foam Cells and Hypocholesterolemia in Mice Lacking the ABC Transporters A1 and G1

(2007) Ruud Out et al.   CIRCULATION RESEARCH