Abnormalities of Mitochondrial Dynamics in the Failing Heart: Normalization Following Long-Term Therapy with Elamipretide

The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age

(2017) Mariya T. Sweetwyne et al.   KIDNEY INTERNATIONAL

Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress

(2015) Luis Alberto Luévano-Martínez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Regulation of Mitochondrial Dynamics by Dynamin-Related Protein-1 in Acute Cardiorenal Syndrome

(2015) M. Sumida et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dysregulation of Mfn2 and Drp-1 proteins in heart failure

(2014) Srikanth Givvimani et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Serendipity and the Discovery of Novel Compounds That Restore Mitochondrial Plasticity

(2014) H H Szeto et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bendavia, a Mitochondria-targeting Peptide, Improves Postinfarction Cardiac Function, Prevents Adverse Left Ventricular Remodeling, and Restores Mitochondria-related Gene Expression in Rats

(2014) Wangde Dai et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of mitochondrial lipids in guiding fission and fusion

(2014) Michael A. Frohman   JOURNAL OF MOLECULAR MEDICINE-JMM

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

(2013) Michael P. Siegel et al.   AGING CELL

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

Global Proteomics and Pathway Analysis of Pressure-Overload–Induced Heart Failure and Its Attenuation by Mitochondrial-Targeted Peptides

(2013) Dao-Fu Dai et al.   Circulation-Heart Failure

Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy

(2013) Valeria Righi et al.   FASEB JOURNAL

Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant

(2013) Erin E. Talbert et al.   JOURNAL OF APPLIED PHYSIOLOGY

Reduction of Early Reperfusion Injury With the Mitochondria-Targeting Peptide Bendavia

(2013) David A. Brown et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

(2013) A. V. Birk et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Cardiolipin and Mitochondrial Phosphatidylethanolamine Have Overlapping Functions in Mitochondrial Fusion inSaccharomyces cerevisiae

(2012) Amit S. Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness*

(2011) Scott K. Powers et al.   CRITICAL CARE MEDICINE

Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury

(2011) H. H. Szeto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

(2011) K. N. Papanicolaou et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel Therapies Targeting Inner Mitochondrial Membrane—From Discovery to Clinical Development

(2011) Hazel H. Szeto et al.   PHARMACEUTICAL RESEARCH

Proteomic alterations of distinct mitochondrial subpopulations in the type 1 diabetic heart: contribution of protein import dysfunction

(2010) Walter A. Baseler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial OPA1, apoptosis, and heart failure

(2009) Le Chen et al.   CARDIOVASCULAR RESEARCH

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

(2009) Rachel M. DeVay et al.   JOURNAL OF CELL BIOLOGY