Novel Therapies Targeting Inner Mitochondrial Membrane—From Discovery to Clinical Development

Reduction of Age-Associated Pathology in Old Mice by Overexpression of Catalase in Mitochondria

(2011) P. M. Treuting et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Development of Mitochondria-targeted Aromatic-cationic Peptides for Neurodegenerative Diseases

(2010) Hazel H. Szeto   Annals of the New York Academy of Sciences

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

(2010) Hui-Young Lee et al.   Cell Metabolism

Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging

(2010) Giuseppe Paradies et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress is required for mechanical ventilation-induced protease activation in the diaphragm

(2010) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease

(2010) Jun Ren et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mitochondrial DNA alterations and reduced mitochondrial function in aging

(2010) Sadie L. Hebert et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial oxidative stress and mammalian healthspan

(2010) Jonathan Wanagat et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity

(2009) Vladimir B. Ritov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies

(2009) Y. N. Antonenko et al.   BIOCHEMISTRY-MOSCOW

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

Mitochondria-Derived Reactive Oxygen Species Mediate Heme Oxygenase-1 Expression in Sheared Endothelial Cells

(2009) Z. Han et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Overexpression of Mn Superoxide Dismutase Does Not Increase Life Span in Mice

(2009) Y. C. Jang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy

(2009) James J Kohler et al.   LABORATORY INVESTIGATION

Ectopic Catalase Expression in Mitochondria by Adeno-Associated Virus Enhances Exercise Performance in Mice

(2009) Dejia Li et al.   PLoS One

Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis

(2009) S. Someya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat

(2008) Edward J. Lesnefsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondria-Penetrating Peptides

(2008) Kristin L. Horton et al.   CHEMISTRY & BIOLOGY

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

(2008) J. M. Forbes et al.   DIABETES

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

(2008) Sanford Levine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Do Mitochondriotropic Antioxidants Prevent Chlorinative Stress-Induced Mitochondrial and Cellular Injury?

(2007) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury

(2007) Hazel H. Szeto   ANTIOXIDANTS & REDOX SIGNALING

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH

Live-cell analysis of cell penetration ability and toxicity of oligo-arginines

(2007) Gisela Tünnemann et al.   JOURNAL OF PEPTIDE SCIENCE