Review
Chemistry, Applied
Chanez Bennacef, Sylvie Desobry-Banon, Laurent Probst, Stephane Desobry
Summary: This review details spherification methods to produce millimetric particles, especially for encapsulation using alginate. The properties of alginate and factors impacting its gelation are discussed, and interest in using copolymers for spherification is investigated. Alginate composite gels can enhance encapsulation efficiency and stability, making alginate a promising encapsulation material.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Faith Seke, Vimbainashe E. Manhivi, Retha M. Slabbert, Yasmina Sultanbawa, Dharini Sivakumar
Summary: This study aimed to improve the bioaccessibility of anthocyanins in Natal plum by using microencapsulation techniques. The highest encapsulation efficiency and anthocyanin bioaccessibility were achieved with alginate/psyllium mucilage beads.
Review
Chemistry, Physical
Kun Qian, Randall E. Winans, Tao Li
Summary: Understanding the nanostructures of liquid electrolytes is crucial for enhancing electrochemical energy storage capacities, but the solvation structures and molecular dynamics in electrolytes are difficult to probe. Small-angle X-ray scattering (SAXS) offers unique insights into molecular clusters and ion pairs in electrolytes, with excellent time-resolution for studying molecular dynamics. This review focuses on the microscopic understanding of liquid electrolytes by SAXS and highlights the unique capabilities of X-ray scattering for nanostructure characterization.
ADVANCED ENERGY MATERIALS
(2021)
Article
Chemistry, Applied
Jingyi Yang, Jiangliu Song, Song Miao, Yanxiang Gao, Like Mao
Summary: This study developed novel gel beads with bigel structures based on alginate hydrogel and glycerol monostearate oleogel. The beads were able to encapsulate lipophilic and hydrophilic bioactives simultaneously. The increase in oleogel content led to larger bead size, higher oil filling level, and lower mechanical strength. The swelling of beads was inhibited by the increase in oleogel content. The gel structures provided good protection for curcumin, and about 70% of the original curcumin was retained after a 40-day storage test. The study provided valuable information for the development of functional food materials.
FOOD HYDROCOLLOIDS
(2024)
Article
Food Science & Technology
Esther Santamaria, Alicia Maestro, Carmen Gonzalez
Summary: Nanoemulsions were prepared using a low-energy emulsification method and encapsulated into alginate beads. The beads were coated with chitosan and pullulan to improve the release kinetics of carvacrol. The chitosan-coated beads showed sustained release patterns and avoided the initial burst effect.
Article
Materials Science, Multidisciplinary
Kakeru Obayashi, Kazutaka Kamitani, Chien-Wei Chu, Ryosuke Kawatoko, Chao-Hung Cheng, Atsushi Takahara, Ken Kojio
Summary: The internal structure of polyurethane adhesive undergoes changes during lap shear deformation, with an increase in the spacing of hard segment domains and the merging of tilt angle with the stretching direction. These findings are of great significance for the practical design of adhesives.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Food Science & Technology
Alejandro Londono-Moreno, Zayra Mundo-Franco, Margarita Franco-Colin, Carolina Buitrago-Arias, Martha Lucia Arenas-Ocampo, Antonio Ruperto Jimenez-Aparicio, Edgar Cano-Europa, Brenda Hildeliza Camacho-Diaz
Summary: The aim of this study was to develop a microencapsulate of a complex matrix using polysaccharides to protect and control the release of CPC. The results showed that the encapsulation efficiency of the matrix-type encapsulates increased as more components were added to the mixtures. Therefore, matrix M4 exhibited an encapsulation efficiency for CPC of 98% and a bioaccessibility of 10.65 +/- 0.65% after the passage of encapsulates through in vitro digestion.
Article
Chemistry, Multidisciplinary
Ezzeldin Metwalli, Klaus Goetz, Tobias Zech, Christian Baer, Isabel Schuldes, Anne Martel, Lionel Porcar, Tobias Unruh
Summary: A customized portable SAXS instrument has been constructed and tested at the D22 SANS instrument at ILL, with optimized lead shielding arrangement and double energy threshold X-ray detector to suppress high-energy gamma radiation background. The upgraded SAXS instrument allows for improved signal-to-noise ratio data and combined SAXS and SANS measurements, enabling simultaneous fitting of SAXS and SANS data from the same sample volume for unambiguous interpretation of scattering data. Advanced in situ/real time investigations are now possible, revealing time-resolved complementary nanoscale structural information.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Ivana M. Savic Gajic, Ivan M. Savic, Dragoljub G. Gajic, Aleksandar Dosic
Summary: This study aimed to develop an ultrasound-assisted extraction method for carotenoids from orange peel using olive oil as a solvent, finding optimal extraction conditions and preparing stable Ca-alginate beads enriched with carotenoids in olive oil. The results indicated that extraction time had the greatest impact on carotenoid content.
Article
Multidisciplinary Sciences
David N. Azulay, Oliver Spaeker, Mnar Ghrayeb, Michaela Wilsch-Brauninger, Ernesto Scoppola, Manfred Burghammer, Ivo Zizak, Luca Bertinetti, Yael Politi, Liraz Chai
Summary: Biofilms are multicellular microbial communities encased in an extracellular matrix, with phenotypic heterogeneity enhancing their survival. The molecular structures, elemental distribution, and possible linkages within biofilms remain unexplored, showcasing the importance of molecular-level heterogeneity in shaping biofilm physiology and development.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biochemistry & Molecular Biology
Ying Li, Qike Li, Richard E. Gillilan, Alireza Abbaspourrad
Summary: This study reveals the reversible modulation of protein-protein and protein-chromophore interactions of Cphycocyanin (C-PC) from Spirulina platensis under hydrostatic pressure. The results show that high pressures can disassemble C-PC into monomers or detached subunits, accompanied by protein unfolding. The pressure-induced changes in structure and color can be precisely manipulated and reversed. This knowledge can be used to design new delivery and optical materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Chonnipa Wongverawattanakul, Phim On Suklaew, Charoonsri Chusak, Sirichai Adisakwattana, Thavaree Thilavech
Summary: The encapsulation of Mesona chinensis polyphenols with alginate as a carrier can improve their bioaccessibility and biological activity in the gastrointestinal tract. The optimal encapsulation condition is 75% MCE, 1.5% alginate, and 3% CaCl2 solution, which provides the highest encapsulation efficiency and suitable particle diameter.
Article
Engineering, Biomedical
Yoon Jeong, Joseph Irudayaraj
Summary: In order to sequester prokaryotic cells in a biofilm-like niche, it is crucial to create a microenvironment that reflects the heterogeneous nature of biological systems. This study presents an artificial long-term confinement model using natural alginate hydrogels that can support the growth and survival of organisms for over 10 days. The confinement platform allows for the encapsulation of bacterial cells in both the core and shell layers, with tunable thickness and number of shell layers.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Yi Zhang, Wenkai Zhang, Tim Snow, Ying Ju, Yang Liu, Andrew J. Smith, Sujay Prabakar
Summary: This study investigated the changes in structure and stability of ABPs during crosslinking using GA or EDC at different concentrations through synchrotron small-angle X-ray scattering and thermal and colorimetric methods. The findings reveal that telopeptidyl-helical linkages are preferred at low crosslinker concentrations, while excess crosslinking leads to structural changes and plateauing of stabilities.
ACTA BIOMATERIALIA
(2022)
Article
Food Science & Technology
Carlos Pasqualin Cavalheiro, Claudia Ruiz-Capillas, Ana Maria Herrero, Tatiana Pintado
Summary: The addition of E. faecium CECT 410, either as free cells or in alginate beads, was effective in producing probiotic dry-fermented sausages, with acceptable weight losses and lower pH values during ripening and storage. The sausages with probiotics via alginate beads had higher protein and fat content, but lower moisture content, without affecting lipid oxidation. Counts of E. faecium CECT 410 remained high throughout the ripening and storage periods, making it an effective method for probiotic sausage production.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Maria Victoria Traffano-Schiffo, Tony Chuquizuta, Marta Castro-Giraldez, Pedro J. Fito
Summary: The study aims to develop a scientific method to determine the level of damage in poultry breast tenders affected by Deep Pectoral Myopathy, identifying three levels of damage based on significant variables in muscle tissue metabolism. This research provides an objective and scientific methodology for categorizing and assessing deep pectoral myopathy in broilers, enabling the detection and characterization of affected chickens.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Engineering, Chemical
Maria Victoria Traffano-Schiffo, Marta Castro-Giraldez, Ricardo J. Colom, Pau Talens, Pedro J. Fito
Summary: The study analyzed the dielectric spectra of chicken meat postmortem to predict its metabolic status. Changes in dielectric properties, including protein hydrolysis and various dispersion phenomena, can help understand the quality and safety state of meat.
JOURNAL OF FOOD ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Juan Angel Tomas-Egea, Maria Victoria Traffano-Schiffo, Marta Castro-Giraldez, Pedro J. Fito
Summary: The study explores the combined drying of raw potatoes using hot air drying and microwave radiation, finding that microwave radiation primarily increases the internal energy of potatoes, leading to rapid and efficient drying.
APPLIED SCIENCES-BASEL
(2021)
Review
Materials Science, Ceramics
Brianne Salvati, Patricio Santagapita, Mercedes Perullini
Summary: Alginate-based nanosized particles show promising features in drug delivery applications, but the fast gelling rate limits the adequate inclusion of bioactive molecules.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Leidy Ricaurte, Maria de Jesus Perea-Flores, Juan Vicente Mendez-Mendez, Patricio Roman Santagapita, Maria Ximena Quintanilla-Carvajal
Summary: This study evaluated the effect of HOPO concentration on various properties of NFs and found that higher HOPO concentration decreased the elastic modulus of NFs and increased their adhesive properties, making them suitable for use as edible packaging.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Applied
Gabriela Jaramillo Sanchez, Eunice V. Contigiani, Stella M. Alzamora, Patricio R. Santagapita
Summary: This study aimed to evaluate the effect of ozone in aqueous phase on blueberry surface through analyzing the changes in epicuticular waxes and color. It was found that ozone treatment led to chemical modifications in the epicuticular waxes, but did not significantly affect the color, indicating a preserved quality of the blueberries post-treatment.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Applied
Camila Regina Hackenhaar, Carolina Flores Rosa, Eli Emanuel Esparza Flores, Patricio Roman Santagapita, Manuela Poletto Klein, Plinho Francisco Hertz
Summary: In this study, a biocomposite made of alginate and gelatin crosslinked with genipin was developed for immobilizing beta-galactosidase. The microstructure, thermal stability, and operational stability of the immobilized enzyme were analyzed using thermal analyses and SAXS. The results showed that the addition of genipin and enzyme significantly reduced the size and density of the Ca(II)-alginate rods in the biocomposite. The immobilized beta-galactosidase exhibited high storage stability and retained a high relative activity after multiple reuses in lactose hydrolysis.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Chemical
Juan Angel Tomas-Egea, Marta Castro-Giraldez, Ricardo J. Colom, Pedro J. Fito
Summary: This study compares the application of Differential Scanning Calorimetry (DSC) and Photospectrometry in the Radiofrequency Range (PFR) for measuring the thermal properties of chicken breast during the freezing process. The results show that PFR provides similar results to DSC in measuring critical temperatures.
JOURNAL OF FOOD ENGINEERING
(2022)
Article
Polymer Science
Yesica Vanesa Rojas-Munoz, Patricio Roman Santagapita, Maria Ximena Quintanilla-Carvajal
Summary: This study evaluated the effect of wall materials on the viability of Lactobacillus fermentum during the encapsulation process and under simulated gastrointestinal conditions. The optimal mixture formulation was determined, and its effectiveness in improving bacterial survival was confirmed through experiments and modeling.
Article
Chemistry, Applied
Ignacio Zazzali, Gabriela Jaramillo, Julieta Gabilondo, Luana Peixoto Mallmann, Eliseu Rodrigues, Mercedes Perullini, Patricio R. Santagapita
Summary: The study focuses on the extraction of phenolic compounds from artichoke harvest waste using green extractions. The extract was encapsulated into Ca(II)-alginate beads, and the physico-chemical and structural properties of the beads were optimized. The study also investigated the transfer of phenolic compounds from the waste to the beads, and the relationship between synthesis conditions and the microstructure of the beads.
FOOD HYDROCOLLOIDS FOR HEALTH
(2022)
Article
Food Science & Technology
Tatiana Rocio Aguirre-Calvo, Natalia Sosa, Tamara Anahi Lopez, Maria Ximena Quintanilla-Carvajal, Mercedes Perullini, Patricio Roman Santagapita
Summary: The study revealed that Ca(II)-alginate beads containing beet stem extract showed significantly increased phenolic compounds content and antioxidant capacity in cookies and Turkish delights, protecting these compounds during oral and gastric digestion phases.
FOOD CHEMISTRY: MOLECULAR SCIENCES
(2022)
Article
Engineering, Chemical
Cecilia G. Gimenez, Maria Victoria Traffano-Schiffo, Sonia C. Sgroppo, Carola A. Sosa
Summary: Consumers' interest in a high-quality healthy diet has led to the design and development of new products rich in bioactive compounds. In this study, PVC was found to better preserve polyphenols, antioxidant activity, and carotenoids at a storage temperature of 25 degrees Celsius. Higher storage temperatures accelerated undesirable changes in sensory attributes.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
