Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

(2014) Matjaz Rokavec et al.   JOURNAL OF CLINICAL INVESTIGATION

Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells

(2014) Jeannine Diesch et al.   PLoS One

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

(2013) Wai Leong Tam et al.   CANCER CELL

Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition

(2013) L Guo et al.   ONCOGENE

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

The HAT/HDAC interplay: Multilevel control of STAT signaling

(2012) Laura Icardi et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Inhibition of the IL-6 signaling pathway: A strategy to combat chronic inflammatory diseases and cancer

(2012) Parvin Ataie-Kachoie et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Novel Interactions between NFATc1 (Nuclear Factor of Activated T Cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) Mediate G Protein-coupled Receptor Agonist, Thrombin-induced Biphasic Expression of Cyclin D1, with First Phase Influencing Cell Migration and Second Phase Directing Cell Proliferation

(2012) Venkatesh Kundumani-Sridharan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon Regulatory Factor 1 Transactivates Expression of Human DNA Polymerase η in Response to CarcinogenN-Methyl-N′-nitro-N-nitrosoguanidine

(2012) Hongyan Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells

(2012) K Belguise et al.   ONCOGENE

MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1

(2012) S Yang et al.   ONCOGENE

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct reprogramming of stem cell properties in colon cancer cells by CD44

(2011) Ying-Jhen Su et al.   EMBO JOURNAL

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro

(2011) C. HUANG et al.   NEOPLASMA

IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

(2011) A Rojas et al.   ONCOGENE

Annexin A1 attenuates EMT and metastatic potential in breast cancer

(2010) Sabine Maschler et al.   EMBO Molecular Medicine

Nonhistone protein acetylation as cancer therapy targets

(2010) Brahma N Singh et al.   Expert Review of Anticancer Therapy

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

International Trends in Colorectal Cancer Incidence Rates

(2009) M. M. Center et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Serum interleukin-6 levels in colorectal cancer patients—a summary of published results

(2009) Heike Knüpfer et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Acetylation and activation of STAT3 mediated by nuclear translocation of CD44

(2009) Jia-Lin Lee et al.   JOURNAL OF CELL BIOLOGY

Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

(2009) Yaping Sun et al.   JOURNAL OF IMMUNOLOGY

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

(2009) Yongzhan Nie et al.   NATURE CELL BIOLOGY

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

(2009) N J Sullivan et al.   ONCOGENE

STAT3 as a target for inducing apoptosis in solid and hematological tumors

(2008) Khandaker Al Zaid Siddiquee et al.   CELL RESEARCH

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS