Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals

Infiltrating Macrophages Promote Prostate Tumorigenesis via Modulating Androgen Receptor-Mediated CCL4-STAT3 Signaling

(2013) L.-Y. Fang et al.   CANCER RESEARCH

Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation

(2013) Kouji Izumi et al.   EMBO Molecular Medicine

Increased Chemosensitivity via Targeting Testicular Nuclear Receptor 4 (TR4)-Oct4-Interleukin 1 Receptor Antagonist (IL1Ra) Axis in Prostate Cancer CD133+Stem/Progenitor Cells to Battle Prostate Cancer

(2013) Dong-Rong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Androgen Deprivation Therapies with Anti-androgens Casodex/Bicalutamide or MDV3100/EnzalutamideversusAnti-androgen Receptor ASC-J9® Lead to PromotionversusSuppression of Prostate Cancer Metastasis

(2013) Tzu-Hua Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent advances in the study of testicular nuclear receptor 4

(2013) Xian-fan Ding et al.   Journal of Zhejiang University-SCIENCE B

Endothelial Cells Enhance Prostate Cancer Metastasis via IL-6->Androgen Receptor->TGF- ->MMP-9 Signals

(2013) X. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease

(2013) L. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPAR  and TR4 for Survival

(2012) S. Mahajan et al.   JOURNAL OF IMMUNOLOGY

The roles of testicular nuclear receptor 4 (TR4) in male fertility-priapism and sexual behavior defects in TR4 knockout mice

(2011) Loretta L Collins et al.   Reproductive Biology and Endocrinology

Elevated plasma tissue inhibitor of metalloproteinase-1 levels predict decreased survival in castration-resistant prostate cancer patients

(2010) William K. Oh et al.   CANCER

Nuclear Orphan Receptor TAK1/TR4-Deficient Mice Are Protected Against Obesity-Linked Inflammation, Hepatic Steatosis, and Insulin Resistance

(2010) H. S. Kang et al.   DIABETES

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation

(2009) S. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the Osteopontin/Matrix Metalloproteinase-9 Pathway Correlates with Prostate Cancer Progression

(2008) G. Castellano et al.   CLINICAL CANCER RESEARCH

Oxidative Stress Stimulates Testicular Orphan Receptor 4 through Forkhead Transcription Factor Forkhead Box O3a

(2008) Gonghui Li et al.   ENDOCRINOLOGY