Expressions of IGF-1, ERK, GLUT4, IRS-1 in metabolic syndrome complicated with colorectal cancer and their associations with the clinical characteristics of CRC

Inhibiting IGF-1R attenuates cell proliferation and VEGF production in IGF-1R over-expressing EGFR mutant non-small cell lung cancer cells

(2017) Chang Dong Yeo et al.   EXPERIMENTAL LUNG RESEARCH

Prevalence and risk factors of advanced colorectal neoplasms in asymptomatic Korean people between 40 and 49 years of age

(2017) Ja Eun Koo et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Diets link metabolic syndrome and colorectal cancer development

(2017) Jirakrit Saetang et al.   ONCOLOGY REPORTS

Characterization of stromal vascular fraction and adipose stem cells from subcutaneous, preperitoneal and visceral morbidly obese human adipose tissue depots

(2017) Karina Ribeiro Silva et al.   PLoS One

ApoA-IV improves insulin sensitivity and glucose uptake in mouse adipocytes via PI3K-Akt Signaling

(2017) Xiaoming Li et al.   Scientific Reports

Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human

(2016) Daniele Lettieri-Barbato et al.   Aging-US

Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes

(2016) Weihua Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Metformin may protect nondiabetic breast cancer women from metastasis

(2016) Sahar Mohammed EL-Haggar et al.   CLINICAL & EXPERIMENTAL METASTASIS

Atypical defects resulting in growth hormone insensitivity

(2016) Jan M. Wit et al.   GROWTH HORMONE & IGF RESEARCH

Visfatin stimulates endometrial cancer cell proliferation via activation of PI3K/Akt and MAPK/ERK1/2 signalling pathways

(2016) Yingmei Wang et al.   GYNECOLOGIC ONCOLOGY

Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway

(2016) Moon Hee Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Maternal flaxseed oil intake during lactation changes body fat, inflammatory markers and glucose homeostasis in the adult progeny: role of gender dimorphism

(2016) Deysla Sabino Guarda et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Regulation of dendritic cell function by insulin/IGF-1/PI3K/Akt signaling through klotho expression

(2016) Nguyen Thi Xuan et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy

(2016) Nam Hee Kim et al.   MEDICINE

Dietary protein and fat intake in relation to risk of colorectal adenoma in Korean

(2016) Sun Young Yang et al.   MEDICINE

Higher Expression of Proteins in IGF/IR Axes in Colorectal Cancer is Associated with Type 2 Diabetes Mellitus

(2016) Jing Ding et al.   PATHOLOGY & ONCOLOGY RESEARCH

Insulin-like growth factor-related components and the risk of liver cancer in a nested case-control study

(2016) Yasushi Adachi et al.   TUMOR BIOLOGY

Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation

(2016) HYUN JOO JANG et al.   Oncology Letters

Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation

(2016) Marina Saisana et al.   Oncotarget

Circulating levels of IGF-1, IGFBP-3, and IGF-1/IGFBP-3 molar ratio and colorectal adenomas: A meta-analysis

(2015) Yeong Sook Yoon et al.   Cancer Epidemiology

Krüppel-like factor 14 increases insulin sensitivity through activation of PI3K/Akt signal pathway

(2015) Min Yang et al.   CELLULAR SIGNALLING

Histidine supplementation alleviates inflammation in the adipose tissue of high-fat diet-induced obese rats via the NF-κB- and PPARγ-involved pathways

(2014) Xiaowei Sun et al.   BRITISH JOURNAL OF NUTRITION

Insulin-Like Growth Factors (IGF), IGF-Binding Proteins (IGFBP), and Vascular Endothelial Growth Factor (VEGF) in Blood Serum of Patients with Colorectal Cancer

(2014) N. E. Kushlinskii et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice

(2014) Ashish Saxena et al.   CANCER LETTERS

Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway

(2014) Gopalsamy Rajiv Gandhi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

(2014) Collin Y. Ewald et al.   NATURE

Olive leaf extract suppresses messenger RNA expression of proinflammatory cytokines and enhances insulin receptor substrate 1 expression in the rats with streptozotocin and high-fat diet–induced diabetes

(2014) Ya-Nan Liu et al.   NUTRITION RESEARCH

Calycosin Suppresses Breast Cancer Cell Growth via ERβ-Dependent Regulation of IGF-1R, p38 MAPK and PI3K/Akt Pathways

(2014) Jian Chen et al.   PLoS One

Elevated cyclin D1 expression is governed by plasma IGF-1 through Ras/Raf/MEK/ERK pathway in rumen epithelium of goats supplying a high metabolizable energy diet

(2013) J. Lu et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Metabolic syndrome and colorectal cancer: Is hyperinsulinemia/insulin receptor-mediated angiogenesis a critical process?

(2013) Jane Jijun Liu et al.   Journal of Geriatric Oncology

Mitogenic and anti-apoptotic effects of insulin in endometrial cancer are phosphatidylinositol 3-kinase/Akt dependent

(2012) Yingmei Wang et al.   GYNECOLOGIC ONCOLOGY

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium

(2011) A. Abbas et al.   DIABETES

Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice

(2011) Jie Tian et al.   JOURNAL OF CLINICAL INVESTIGATION

NBS1 is required for IGF-1 induced cellular proliferation through the Ras/Raf/MEK/ERK cascade

(2008) Arunee Hematulin et al.   CELLULAR SIGNALLING