Pim-3 enhances melanoma cell migration and invasion by promoting STAT3 phosphorylation

STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression

(2017) K-J Kim et al.   ONCOGENE

Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells

(2017) Qie Guo et al.   Oncotarget

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis

(2017) Eva M. Putz et al.   OncoImmunology

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Innate immunity and inflammation

(2016) Tsan Sam Xiao   Cellular & Molecular Immunology

MCP-1-induced ERK/GSK-3β/Snail signaling facilitates the epithelial–mesenchymal transition and promotes the migration of MCF-7 human breast carcinoma cells

(2016) Shun Li et al.   Cellular & Molecular Immunology

Epithelial–mesenchymal transition (EMT) and metastasis: yes, no, maybe?

(2016) Maren Diepenbruck et al.   CURRENT OPINION IN CELL BIOLOGY

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma

(2016) Hui-Hui Cao et al.   Scientific Reports

Aberrant Expression of Pim-3 Promotes Proliferation and Migration of Ovarian Cancer Cells

(2015) Hao Zhuang et al.   Asian Pacific Journal of Cancer Prevention

Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus

(2015) Deshan Ren et al.   Cellular & Molecular Immunology

The novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes

(2015) YU-KYOUNG PARK et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling

(2015) Xin Yin et al.   Journal of Hematology & Oncology

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

(2015) Niina M. Santio et al.   PLoS One

N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial–mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling

(2014) Myung-Jin Kim et al.   CANCER LETTERS

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

(2014) G Denecker et al.   CELL DEATH AND DIFFERENTIATION

Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses

(2014) Zhiyong Ma et al.   Cellular & Molecular Immunology

Immunotherapy for Hepatoma Using a Dual-Function Vector with Both Immunostimulatory and Pim-3-Silencing Effects

(2014) Q. Guo et al.   MOLECULAR CANCER THERAPEUTICS

Pim-3 promotes human pancreatic cancer growth by regulating tumor vasculogenesis

(2014) BIN LIU et al.   ONCOLOGY REPORTS

Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine

(2013) Dapeng Xu et al.   CANCER BIOLOGY & THERAPY

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells

(2012) Rahul Purwar et al.   NATURE MEDICINE

Identification of a phenanthrene derivative as a potent anticancer drug with Pim kinase inhibitory activity

(2011) Ying-Ying Wang et al.   CANCER SCIENCE

Roles of Pim-3, a novel survival kinase, in tumorigenesis

(2011) Naofumi Mukaida et al.   CANCER SCIENCE

IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway

(2011) A. Yadav et al.   MOLECULAR CANCER RESEARCH

Pim protein kinase-3 is regulated by TNF-α and promotes endothelial cell sprouting

(2011) Handong Yang et al.   MOLECULES AND CELLS

Epithelial–mesenchymal transition in the skin

(2010) Motonobu Nakamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

PIM Kinase Inhibitors Downregulate STAT3Tyr705 Phosphorylation

(2010) M. Chang et al.   MOLECULAR CANCER THERAPEUTICS

Melanocytes in development and cancer

(2009) Audrey Uong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor lymphangiogenesis and melanoma metastasis

(2008) Matthias Rinderknecht et al.   JOURNAL OF CELLULAR PHYSIOLOGY