A two-state model for the kinetics of competitive radioligand binding

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

On the different experimental manifestations of two-state ‘induced-fit’ binding of drugs to their cellular targets

(2016) Georges Vauquelin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Kinetic Aspects of the Interaction between Ligand and G Protein-Coupled Receptor: The Case of the Adenosine Receptors

(2016) Dong Guo et al.   CHEMICAL REVIEWS

A universal homogeneous assay for high-throughput determination of binding kinetics

(2015) Felix Schiele et al.   ANALYTICAL BIOCHEMISTRY

Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists

(2015) Jacobus P.D. van Veldhoven et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Characterization of 12 GnRH peptide agonists - a kinetic perspective

(2015) Indira Nederpelt et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Role of Binding Kinetics in GPCR Drug Discovery

(2015) David Swinney et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The drug–target residence time model: a 10-year retrospective

(2015) Robert A. Copeland   NATURE REVIEWS DRUG DISCOVERY

Scintillation proximity assay (SPA) as a new approach to determine a ligand’s kinetic profile. A case in point for the adenosine A1 receptor

(2015) Lizi Xia et al.   Purinergic Signalling

Kv11.1 (hERG)-induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv11.1 (hERG) inhibitors

(2014) Z Yu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drug-Target Residence Time-A Case for G Protein-Coupled Receptors

(2014) Dong Guo et al.   MEDICINAL RESEARCH REVIEWS

Structure–Kinetic Relationships—An Overlooked Parameter in Hit-to-Lead Optimization: A Case of Cyclopentylamines as Chemokine Receptor 2 Antagonists

(2013) Maris Vilums et al.   JOURNAL OF MEDICINAL CHEMISTRY

Functional efficacy of adenosine A2A receptor agonists is positively correlated to their receptor residence time

(2012) Dong Guo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional and Biochemical Rationales for the 24-Hour-Long Duration of Action of Olodaterol

(2011) P. Casarosa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)

(2011) S. Offermanns et al.   PHARMACOLOGICAL REVIEWS

Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a ‘two-step’ competition binding approach

(2010) A Packeu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: Application to (R)-dimethindene occupancy of central histamine H1receptors

(2009) Siobhan Malany et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Modelling the activation of G-protein coupled receptors by a single drug

(2009) P.J. Woodroffe et al.   MATHEMATICAL BIOSCIENCES

Mathematical modelling of signalling in a two-ligand G-protein coupled receptor system: Agonist–antagonist competition

(2009) L.J. Bridge et al.   MATHEMATICAL BIOSCIENCES

Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor

(2006) Mark R Dowling et al.   BRITISH JOURNAL OF PHARMACOLOGY