Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage

Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture

(2018) Zhiwen Zhang et al.   BIOSCIENCE REPORTS

Resveratrol Alleviates Inflammatory Responses and Oxidative Stress in Rat Kidney Ischemia-Reperfusion Injury and H2O2-Induced NRK-52E Cells via the Nrf2/TLR4/NF-κB Pathway

(2018) Jiawei Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration

(2018) Elizabeth S. Silagi et al.   MATRIX BIOLOGY

Resveratrol, an antioxidant, protects spinal cord injury in rats by suppressing MAPK pathway

(2018) Song Fu et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration

(2017) Chencheng Feng et al.   Oxidative Medicine and Cellular Longevity

Autophagy: A double-edged sword in intervertebral disk degeneration

(2016) Shu-Jun Zhang et al.   CLINICA CHIMICA ACTA

Resveratrol attenuated TNF-α–induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway

(2016) Xiao-Hu Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Molecular mechanisms of biological aging in intervertebral discs

(2016) Nam V. Vo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

MMPs and ADAMTSs in intervertebral disc degeneration

(2015) Wen-Jun Wang et al.   CLINICA CHIMICA ACTA

Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition

(2015) KANG XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Function of Autophagy in Neurodegenerative Diseases

(2015) Yoshimitsu Kiriyama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy prevents age-related OA

(2015) João H. Duarte   Nature Reviews Rheumatology

Mechanics and biology in intervertebral disc degeneration: a vicious circle

(2015) P.-P.A. Vergroesen et al.   OSTEOARTHRITIS AND CARTILAGE

Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

(2015) Satoshi Suzuki et al.   ARTHRITIS RESEARCH & THERAPY

Responses and adaptations of intervertebral disc cells to microenvironmental stress: a possible central role of autophagy in the adaptive mechanism

(2014) Libo Jiang et al.   CONNECTIVE TISSUE RESEARCH

The prosurvival role of autophagy in resveratrol-induced cytotoxicity in GH3 cells

(2014) XUEXIN ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells

(2014) Wei Jiang et al.   Scientific Reports

Review of recent data on the metabolism, biological effects, and toxicity of resveratrol in humans

(2013) Charles-Henry Cottart et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats

(2012) Wei Ye et al.   CONNECTIVE TISSUE RESEARCH

Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: Implications for diabetic intervertebral disc degeneration

(2012) Libo Jiang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL