Therapy-Related Myeloid Neoplasms

Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases

(2015) Chi Young Ok et al.   LEUKEMIA RESEARCH

Clinicopathologic and molecular characterization of myeloid neoplasms harboring isochromosome 17(q10)

(2014) Valeria Visconte et al.   AMERICAN JOURNAL OF HEMATOLOGY

A Prognostic Model of Therapy-Related Myelodysplastic Syndrome for Predicting Survival and Transformation to Acute Myeloid Leukemia

(2014) Alfonso Quintás-Cardama et al.   Clinical Lymphoma Myeloma & Leukemia

Nodular Lymphocyte Predominant Hodgkin Lymphoma: Biology, Diagnosis and Treatment

(2014) Anupama Goel et al.   Clinical Lymphoma Myeloma & Leukemia

SETBP1 mutations in 106 patients with therapy-related myeloid neoplasms

(2014) E. Fabiani et al.   HAEMATOLOGICA

Why is there so much therapy-related AML and MDS and so little therapy-related CML?

(2014) Robert Peter Gale et al.   LEUKEMIA RESEARCH

Therapy-related AML: A slip of the lip can sink a ship

(2014) Robert Peter Gale et al.   LEUKEMIA RESEARCH

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

(2014) Terrence N. Wong et al.   NATURE

Predictive factors for latency period and a prognostic model for survival in patients with therapy-related acute myeloid leukemia

(2013) Moshe C. Ornstein et al.   AMERICAN JOURNAL OF HEMATOLOGY

Evolving risk of therapy-related acute myeloid leukemia following cancer chemotherapy among adults in the United States, 1975-2008

(2013) L. M. Morton et al.   BLOOD

Recent progress toward epigenetic therapies: the example of mixed lineage leukemia

(2013) T. Neff et al.   BLOOD

Donor cell-derived leukemia after cord blood transplantation and a review of the literature: differences between cord blood and BM as the transplant source

(2013) H Shiozaki et al.   BONE MARROW TRANSPLANTATION

Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia

(2013) A. H. Shih et al.   HAEMATOLOGICA

The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia

(2013) M A Jacoby et al.   LEUKEMIA

Application of the International Prognostic Scoring System-Revised in therapy-related myelodysplastic syndromes and oligoblastic acute myeloid leukemia

(2013) C Y Ok et al.   LEUKEMIA

SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations

(2013) M Meggendorfer et al.   LEUKEMIA

Somatic SETBP1 mutations in myeloid malignancies

(2013) Hideki Makishima et al.   NATURE GENETICS

Patterns of second primary malignancy risk in multiple myeloma patients before and after the introduction of novel therapeutics

(2013) P Razavi et al.   Blood Cancer Journal

Acute Myeloid Leukemia and Myelodysplastic Syndromes After Radiation Therapy Are Similar to De Novo Disease and Differ From Other Therapy-Related Myeloid Neoplasms

(2012) Valentina Nardi et al.   JOURNAL OF CLINICAL ONCOLOGY

Germline mutations in the DNA damage response genesBRCA1,BRCA2,BARD1andTP53in patients with therapy related myeloid neoplasms

(2012) Eduard Schulz et al.   JOURNAL OF MEDICAL GENETICS

IDH1 and IDH2 mutations in therapy-related myelodysplastic syndrome and acute myeloid leukemia are associated with a normal karyotype and with der(1;7)(q10;p10)

(2012) M K Westman et al.   LEUKEMIA

Mutations of epigenetic regulators and of the spliceosome machinery in therapy-related myeloid neoplasms and in acute leukemias evolved from chronic myeloproliferative diseases

(2012) M T Voso et al.   LEUKEMIA

Therapy-related acute myeloid leukemia with favorable cytogenetics: Still favorable?

(2012) Ibrahim Aldoss et al.   LEUKEMIA RESEARCH

Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy

(2011) Monika M. Pichler et al.   BRITISH JOURNAL OF HAEMATOLOGY

Myeloid neoplasms with isolated isochromosome 17q represent a clinicopathologic entity associated with myelodysplastic/myeloproliferative features, a high risk of leukemic transformation, and wild-type TP53

(2011) Rashmi Kanagal-Shamanna et al.   CANCER

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study

(2011) O. Kosmider et al.   HAEMATOLOGICA

Identification of a Novel TP53 Cancer Susceptibility Mutation Through Whole-Genome Sequencing of a Patient With Therapy-Related AML

(2011) Daniel C. Link   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparative molecular analysis of therapy-related and de novo acute promyelocytic leukemia

(2011) T. Ottone et al.   LEUKEMIA RESEARCH

PROGNOSIS AND THERAPY WHEN ACUTE PROMYELOCYTIC LEUKEMIA AND OTHER “GOOD RISK” ACUTE MYELOID LEUKEMIAS OCCUR AS A THERAPY-RELATED MYELOID NEOPLASM

(2011) Richard A. Larson et al.   Mediterranean Journal of Hematology and Infectious Diseases

The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML

(2010) S. Kayser et al.   BLOOD

The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)

(2009) E. Voskaridou et al.   BLOOD

AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features

(2009) T Haferlach et al.   LEUKEMIA

Influence of DNA damage and repair upon the risk of treatment related leukemia

(2008) Vicent Guillem et al.   LEUKEMIA & LYMPHOMA