The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia

c-Myc Suppression of DNA Double-strand Break Repair

(2015) Zhaozhong Li et al.   NEOPLASIA

Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon

(2013) G. Ramsingh et al.   BLOOD

Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia

(2013) A. H. Shih et al.   HAEMATOLOGICA

The genomic landscape of hypodiploid acute lymphoblastic leukemia

(2013) Linda Holmfeldt et al.   NATURE GENETICS

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression

(2013) H Zheng et al.   ONCOGENE

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

(2012) Tobias Rausch et al.   CELL

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

(2011) F. G. Rucker et al.   BLOOD

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Identification of a Novel TP53 Cancer Susceptibility Mutation Through Whole-Genome Sequencing of a Patient With Therapy-Related AML

(2011) Daniel C. Link   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML

(2010) S. Kayser et al.   BLOOD

Dephosphorylation of γ-H2AX by WIP1: An important homeostatic regulatory event in DNA repair and cell cycle control

(2010) Sung-Hwan Moon et al.   CELL CYCLE

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

(2010) Letetia Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

(2009) J. W. Vardiman et al.   BLOOD

Acquired copy number alterations in adult acute myeloid leukemia genomes

(2009) M. J. Walter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of therapy-related myelodysplasia and acute myeloid leukemia

(2008) J Pedersen-Bjergaard et al.   LEUKEMIA

Influence of DNA damage and repair upon the risk of treatment related leukemia

(2008) Vicent Guillem et al.   LEUKEMIA & LYMPHOMA

Early events in the mammalian response to DNA double-strand breaks

(2008) L. C. Riches et al.   MUTAGENESIS