Kallikrein-related peptidases in lung diseases

Inhibitors of kallikrein-related peptidases: An overview

(2017) Nicolas Masurier et al.   MEDICINAL RESEARCH REVIEWS

Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses

(2017) James T. VanLeuven et al.   PLoS One

Epigenome-wide association study of chronic obstructive pulmonary disease and lung function in Koreans

(2017) Mi Kyeong Lee et al.   Epigenomics

Asthma Exacerbations: Pathogenesis, Prevention, and Treatment

(2017) Jamee R. Castillo et al.   Journal of Allergy and Clinical Immunology-In Practice

A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site

(2017) Marco R. Straus et al.   PLoS One

The kallikrein-related peptidase family: Dysregulation and functions during cancer progression

(2016) T. Kryza et al.   BIOCHIMIE

Kallikreins – The melting pot of activity and function

(2016) Magdalena Kalinska et al.   BIOCHIMIE

Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies

(2016) Margaritis Avgeris et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Chemokine release from human rhinovirus–infected airway epithelial cells promotes fibroblast migration

(2016) Christopher Shelfoon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway smooth muscle enlargement is associated with protease-activated receptor 2/ligand overexpression in patients with difficult-to-control severe asthma

(2016) Michel Aubier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Protease-activated Receptor-2 (PAR-2)-mediated Nf-κB Activation Suppresses Inflammation-associated Tumor Suppressor MicroRNAs in Oral Squamous Cell Carcinoma

(2016) Jeff J. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated Chemoradiotherapy Associated with Survival?

(2016) Dilek Unal et al.   Cancer Research and Treatment

Kallistatin Ameliorates Influenza Virus Pathogenesis by Inhibition of Kallikrein-Related Peptidase 1-Mediated Cleavage of Viral Hemagglutinin

(2015) Chia-Hsing Leu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The miRNA-Kallikrein interactions: Adding a new dimension

(2015) Maria D Pasic et al.   CELL CYCLE

The impact of hypoxemia on serum total and free prostate-specific antigen levels in patients with chronic obstructive pulmonary disease

(2015) Cengiz Ozge et al.   MEDICAL ONCOLOGY

Unleashing the therapeutic potential of human kallikrein-related serine proteases

(2015) Ioannis Prassas et al.   NATURE REVIEWS DRUG DISCOVERY

Kallikrein-related peptidase 13: an independent indicator of favorable prognosis for patients with nonsmall cell lung cancer

(2015) Fabien Gueugnon et al.   TUMOR BIOLOGY

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

(2015) Christopher M. Evans et al.   Nature Communications

Tissue Kallikrein Mediates Pro-Inflammatory Pathways and Activation of Protease-Activated Receptor-4 in Proximal Tubular Epithelial Cells

(2014) Wai Han Yiu et al.   PLoS One

A Quantitative Proteomic Approach to Identify Significantly Altered Protein Networks in the Serum of Patients with Lymphangioleiomyomatosis (LAM)

(2014) Nessa Banville et al.   PLoS One

The diagnostic and prognostic value of serum human kallikrein-related peptidases 11 in non-small cell lung cancer

(2014) Chun-Hua Xu et al.   TUMOR BIOLOGY

An exploration of pathways involved in lung carcinoid progression using gene expression profiling

(2013) Dorian R.A. Swarts et al.   CARCINOGENESIS

Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway

(2013) Thomas Kryza et al.   FASEB JOURNAL

Cleavage Activation of Human-adapted Influenza Virus Subtypes by Kallikrein-related Peptidases 5 and 12

(2013) Brian S. Hamilton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matriptase Proteolytically Activates Influenza Virus and Promotes Multicycle Replication in the Human Airway Epithelium

(2013) A. Beaulieu et al.   JOURNAL OF VIROLOGY

Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD

(2013) Fabio L M Ricciardolo et al.   THORAX

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans

(2012) Rachel A. Myers et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cleavage Activation of the Human-Adapted Influenza Virus Subtypes by Matriptase Reveals both Subtype and Strain Specificities

(2012) B. S. Hamilton et al.   JOURNAL OF VIROLOGY

Targeting the kallikrein-related peptidases for drug development

(2012) Georgia Sotiropoulou et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Human kallikrein-related peptidase 12 (KLK12) splice variants expression in breast cancer and their clinical impact

(2012) Maroulio Talieri et al.   TUMOR BIOLOGY

Epigenetic activation of human kallikrein 13 enhances malignancy of lung adenocarcinoma by promoting N-cadherin expression and laminin degradation

(2011) Ruey-Hwang Chou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer

(2011) Youwei Zhang et al.   CANCER LETTERS

Pentraxin-3 Is a Novel Biomarker of Lung Carcinoma

(2011) E. P. Diamandis et al.   CLINICAL CANCER RESEARCH

Kallikrein-related Peptidase 12 Hydrolyzes Matricellular Proteins of the CCN Family and Modifies Interactions of CCN1 and CCN5 with Growth Factors

(2011) Audrey Guillon-Munos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)

(2010) Peter Goettig et al.   BIOCHIMIE

Alternative Splicing Variant of Kallikrein-Related Peptidase 8 as an Independent Predictor of Unfavorable Prognosis in Lung Cancer

(2010) C. Planque et al.   CLINICAL CHEMISTRY

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

Bradykinin-Induced Lung Inflammation and Bronchoconstriction: Role in Parainfluenze-3 Virus-Induced Inflammation and Airway Hyperreactivity

(2010) K. J. Broadley et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

TMPRSS2 and TMPRSS4 Facilitate Trypsin-Independent Spread of Influenza Virus in Caco-2 Cells

(2010) S. Bertram et al.   JOURNAL OF VIROLOGY

Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases

(2009) Daniel J. Sexton et al.   BIOCHEMICAL JOURNAL

Frequent transcriptional inactivation of Kallikrein 10 gene by CpG island hypermethylation in non-small cell lung cancer

(2009) Youwei Zhang et al.   CANCER SCIENCE

A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: Activation of proteinase-activated receptor 1 and epidermal growth factor receptor

(2009) Lin Gao et al.   EXPERIMENTAL CELL RESEARCH

High kallikrein-related peptidase 6 in non-small cell lung cancer cells: an indicator of tumour proliferation and poor prognosis

(2009) Heuzé-Vourc’h Nathalie et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hyaluronidase Expression and Activity Is Regulated by Pro-Inflammatory Cytokines in Human Airway Epithelial Cells

(2008) María Elena Monzón et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A Multiparametric Serum Kallikrein Panel for Diagnosis of Non-Small Cell Lung Carcinoma

(2008) C. Planque et al.   CLINICAL CANCER RESEARCH

Experimental Rhinovirus Infection Increases Human Tissue Kallikrein Activation in Allergic Subjects

(2008) Sandra C. Christiansen et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Prostate-Specific Kallikreins-2 and -4 Enhance the Proliferation of DU-145 Prostate Cancer Cells through Protease-Activated Receptors-1 and -2

(2008) G. J. Mize et al.   MOLECULAR CANCER RESEARCH

Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma

(2007) Jasmine Singh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

(2007) Kristina Stefansson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY