Involvement of Mitochondria in Neurodegeneration in Multiple Sclerosis

VDAC1 functions in Ca 2+ homeostasis and cell life and death in health and disease

(2018) Varda Shoshan-Barmatz et al.   CELL CALCIUM

Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis

(2018) Graham Campbell et al.   FEBS LETTERS

Mitochondrial retrograde signaling in the nervous system

(2017) Rachel J. Hunt et al.   FEBS LETTERS

The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington’s disease

(2017) Aris A. Polyzos et al.   MECHANISMS OF AGEING AND DEVELOPMENT

No evidence of association between optic neuritis and secondary LHON mtDNA mutations in patients with multiple sclerosis

(2017) Sasan Andalib et al.   MITOCHONDRION

In vivo evidence of oxidative stress in brains of patients with progressive multiple sclerosis

(2017) In-Young Choi et al.   Multiple Sclerosis Journal

Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis

(2017) StevenM LeVine et al.   Neural Regeneration Research

The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years

(2017) Sergio E. Baranzini et al.   TRENDS IN GENETICS

In vivo evidence of oxidative stress in brains of patients with progressive multiple sclerosis

(2017) In-Young Choi et al.   Multiple Sclerosis Journal

MtDNA T4216C variation in multiple sclerosis: a systematic review and meta-analysis

(2016) Sasan Andalib et al.   ACTA NEUROLOGICA BELGICA

Enjoy the Trip: Calcium in Mitochondria Back and Forth

(2016) Diego De Stefani et al.   Annual Review of Biochemistry

Mitochondrial dysfunction in neocortex and hippocampus of olfactory bulbectomized mice, a model of Alzheimer’s disease

(2016) A. V. Avetisyan et al.   BIOCHEMISTRY-MOSCOW

Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions

(2016) Hans Lassmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Stat3, the Need for Design Thinking

(2016) Rui Yang et al.   International Journal of Biological Sciences

Toxicity of cuprizone a Cu2+ chelating agent on isolated mouse brain mitochondria: a justification for demyelination and subsequent behavioral dysfunction

(2016) Mehrdad Faizi et al.   TOXICOLOGY MECHANISMS AND METHODS

Toxicity of cuprizone a Cu2+ chelating agent on isolated mouse brain mitochondria: a justification for demyelination and subsequent behavioral dysfunction

(2016) Mehrdad Faizi et al.   TOXICOLOGY MECHANISMS AND METHODS

Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

(2016) Mona Sadeghian et al.   Scientific Reports

Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection

(2015) Liting Hang et al.   Annals of the New York Academy of Sciences

Structure and function of the mitochondrial calcium uniporter complex

(2015) Diego De Stefani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel Cytoprotective Inhibitors for Apoptotic Endonuclease G

(2015) Dae Song Jang et al.   DNA AND CELL BIOLOGY

A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches

(2015) V. V. Bashinskaya et al.   HUMAN GENETICS

Complex I Subunit Gene Therapy With NDUFA6 Ameliorates Neurodegeneration in EAE

(2015) V. Talla et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Lack of association between mitochondrial DNA G15257A and G15812A variations and multiple sclerosis

(2015) Sasan Andalib et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mitochondrial DNA T4216C and A4917G variations in multiple sclerosis

(2015) Sasan Andalib et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Apoptosis-inducing factor and calpain upregulation in glutamate-induced injury of rat spiral ganglion neurons

(2015) ZHONG-JIA DING et al.   Molecular Medicine Reports

Mitochondrial DNA sequence variation in multiple sclerosis

(2015) Gregory J. Tranah et al.   NEUROLOGY

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

(2014) Scott A. Soleimanpour et al.   CELL

Molecular mechanisms linking neuroinflammation and neurodegeneration in MS

(2014) Erik Ellwardt et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial complex I gene variations; as a potential genetic risk factor in pathogenesis of multiple sclerosis

(2014) Ahmad Poursadegh Zonouzi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Genome-wide association study as a method to analyze the genome architecture in polygenic diseases, with the example of multiple sclerosis

(2014) O. O. Favorova et al.   MOLECULAR BIOLOGY

The central role of mitochondria in axonal degeneration in multiple sclerosis

(2014) Graham R Campbell et al.   Multiple Sclerosis Journal

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Curcumin Inhibits Mitochondrial Injury and Apoptosis from the Early Stage in EAE Mice

(2014) Jinzhou Feng et al.   Oxidative Medicine and Cellular Longevity

MYC and Mitochondrial Biogenesis

(2014) F. Morrish et al.   Cold Spring Harbor Perspectives in Medicine

Recent Mitochondrial DNA Mutations Increase the Risk of Developing Common Late-Onset Human Diseases

(2014) Gavin Hudson et al.   PLoS Genetics

MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

(2013) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial genome changes and neurodegenerative diseases

(2013) Milena Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation

(2013) Kasturi Mitra   BIOESSAYS

Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis

(2013) Mascha S. Recks et al.   CLINICAL IMMUNOLOGY

The role of myelin and oligodendrocytes in axonal energy metabolism

(2013) Aiman S Saab et al.   CURRENT OPINION IN NEUROBIOLOGY

Decoding multiple sclerosis: an update on genomics and future directions

(2013) Jorge R Oksenberg   Expert Review of Neurotherapeutics

Role of oxidative DNA damage in mitochondrial dysfunction and Huntington’s disease pathogenesis

(2013) Sylvette Ayala-Peña   FREE RADICAL BIOLOGY AND MEDICINE

Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

(2013) Rita Perfeito et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distribution of oligodendrocyte loss and mitochondrial toxicity in the cuprizone-induced experimental demyelination model

(2013) P. Acs et al.   JOURNAL OF NEUROIMMUNOLOGY

NADH-dehydrogenase Type-2 Suppresses Irreversible Visual Loss and Neurodegeneration in the EAE Animal Model of MS

(2013) Venu Talla et al.   MOLECULAR THERAPY

Deconstructing Mitochondrial Dysfunction in Alzheimer Disease

(2013) Vega García-Escudero et al.   Oxidative Medicine and Cellular Longevity

Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage

(2013) Scott R. Kennedy et al.   PLoS Genetics

Mitochondria and FOXO3: breath or die

(2013) Judith Hagenbuchner et al.   Frontiers in Physiology

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

(2012) Maarten E. Witte et al.   ACTA NEUROPATHOLOGICA

Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics

(2012) Brian Glancy et al.   BIOCHEMISTRY

Metabolic injury to axons and myelin

(2012) Shigeki Tsutsui et al.   EXPERIMENTAL NEUROLOGY

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Universal heteroplasmy of human mitochondrial DNA

(2012) B. A. I. Payne et al.   HUMAN MOLECULAR GENETICS

Mitochondria and ALS: Implications from novel genes and pathways

(2012) Mauro Cozzolino et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Human Mitochondrial DNA Replication

(2012) I. J. Holt et al.   Cold Spring Harbor Perspectives in Biology

Analysis of the mitochondrial proteome in multiple sclerosis cortex

(2011) Laurie Broadwater et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis

(2011) Jessica L. Zambonin et al.   BRAIN

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

B cells in multiple sclerosis: connecting the dots

(2011) H-Christian von Büdingen et al.   CURRENT OPINION IN IMMUNOLOGY

The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation

(2011) Hakan E. Duran et al.   FERTILITY AND STERILITY

Red blood cell extrudes nucleus and mitochondria against oxidative stress

(2011) Zhong-Wei Zhang et al.   IUBMB LIFE

Crosstalk between mitochondrial (dys)function and mitochondrial abundance

(2011) Sébastien Michel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis

(2011) M. Slee et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

(2011) Joung Hyuck Joo et al.   MOLECULAR CELL

Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination

(2011) S. Venkateswaran et al.   NEUROLOGY

Large scale screening of the mitochondrial DNA reveals no pathogenic mutations but a haplotype associated with multiple sclerosis in Caucasians

(2010) B. Kalman et al.   ACTA NEUROLOGICA SCANDINAVICA

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

Demyelination Increases Axonal Stationary Mitochondrial Size and the Speed of Axonal Mitochondrial Transport

(2010) S. Kiryu-Seo et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial genome and human mitochondrial diseases

(2010) I. O. Mazunin et al.   MOLECULAR BIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes

(2009) Sara Rodriguez-Enriquez et al.   Autophagy

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Enhanced number and activity of mitochondria in multiple sclerosis lesions

(2009) Maarten E Witte et al.   JOURNAL OF PATHOLOGY

Impaired regulation of electron transport chain subunit genes by nuclear respiratory factor 2 in multiple sclerosis

(2009) Ashish Pandit et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

(2009) R. Palty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

The mitochondrial serine protease HtrA2/Omi: an overview

(2008) L Vande Walle et al.   CELL DEATH AND DIFFERENTIATION

Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus

(2008) Tamara Vyshkina et al.   CLINICAL IMMUNOLOGY