Argonaute Proteins and Mechanisms of RNA Interference in Eukaryotes and Prokaryotes

Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute

(2017) Daan C. Swarts et al.   MOLECULAR CELL

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription

(2017) Gloria Jih et al.   NATURE

A heterochromatin-dependent transcription machinery drives piRNA expression

(2017) Peter Refsing Andersen et al.   NATURE

Prokaryotic Argonaute proteins: novel genome-editing tools?

(2017) Jorrit W. Hegge et al.   NATURE REVIEWS MICROBIOLOGY

Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii

(2017) Adrian Zander et al.   Nature Microbiology

A decade of discovery: CRISPR functions and applications

(2017) Rodolphe Barrangou et al.   Nature Microbiology

DNA recognition by an RNA-guided bacterial Argonaute

(2017) Kevin W. Doxzen et al.   PLoS One

Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA

(2016) Naoki Matsumoto et al.   CELL

RNAi in Plants: An Argonaute-Centered View

(2016) Xiaofeng Fang et al.   PLANT CELL

A bacterial Argonaute with noncanonical guide RNA specificity

(2016) Emine Kaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

(2016) Tomohiro Miyoshi et al.   Nature Communications

A Dynamic Search Process Underlies MicroRNA Targeting

(2015) Stanley D. Chandradoss et al.   CELL

Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA

(2015) Daan C. Swarts et al.   NUCLEIC ACIDS RESEARCH

The Functions of MicroRNAs: mRNA Decay and Translational Repression

(2015) Hiro-oki Iwakawa et al.   TRENDS IN CELL BIOLOGY

Regulation of miRNA strand selection: follow the leader?

(2014) Hedda A. Meijer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The complexity of miRNA-mediated repression

(2014) A Wilczynska et al.   CELL DEATH AND DIFFERENTIATION

Identification and characterization of Argonaute gene family and meiosis-enriched Argonaute during sporogenesis in maize

(2014) Lihong Zhai et al.   Journal of Integrative Plant Biology

MicroRNAs Trigger Dissociation of eIF4AI and eIF4AII from Target mRNAs in Humans

(2014) Akira Fukao et al.   MOLECULAR CELL

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

(2014) Hansruedi Mathys et al.   MOLECULAR CELL

DNA-guided DNA interference by a prokaryotic Argonaute

(2014) Daan C. Swarts et al.   NATURE

The evolutionary journey of Argonaute proteins

(2014) Daan C Swarts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-molecule FRET supports the two-state model of Argonaute action

(2014) Adrian Zander et al.   RNA Biology

Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes

(2013) A Maxwell Burroughs et al.   Biology Direct

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

(2013) A. Le Thomas et al.   GENES & DEVELOPMENT

Bacterial Argonaute Samples the Transcriptome to Identify Foreign DNA

(2013) Ivan Olovnikov et al.   MOLECULAR CELL

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Turning catalytically inactive human Argonaute proteins into active slicer enzymes

(2013) Judith Hauptmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs

(2013) K. Rogers et al.   PLANT CELL

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

(2013) G. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small RNAs: Emerging key players in DNA double-strand break repair

(2013) ZhaoQing Ba et al.   Science China-Life Sciences

Structural and functional control of the eukaryotic mRNA decapping machinery

(2012) Marcos Arribas-Layton et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression

(2012) Grzegorz Sienski et al.   CELL

A Role for Small RNAs in DNA Double-Strand Break Repair

(2012) Wei Wei et al.   CELL

Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells

(2012) Julien Béthune et al.   EMBO REPORTS

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

(2012) Hiroshi Nishimasu et al.   NATURE

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

(2012) Jonathan J. Ipsaro et al.   NATURE

Argonaute proteins couple chromatin silencing to alternative splicing

(2012) Maya Ameyar-Zazoua et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The N domain of Argonaute drives duplex unwinding during RISC assembly

(2012) Pieter Bas Kwak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish

(2012) A. A. Bazzini et al.   SCIENCE

Arabidopsis Argonaute10 Specifically Sequesters miR166/165 to Regulate Shoot Apical Meristem Development

(2011) Hongliang Zhu et al.   CELL

RNA silencing in Monterey

(2011) O. S. Rissland et al.   DEVELOPMENT

3′ End Formation of PIWI-Interacting RNAs In Vitro

(2011) Shinpei Kawaoka et al.   MOLECULAR CELL

GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets

(2011) Joerg E. Braun et al.   MOLECULAR CELL

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Production of artificial piRNAs in flies and mice

(2011) F. Muerdter et al.   RNA

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

(2009) Kira S Makarova et al.   Biology Direct

An Effector of RNA-Directed DNA Methylation in Arabidopsis Is an ARGONAUTE 4- and RNA-Binding Protein

(2009) Xin-Jian He et al.   CELL

The Sequential Action of miR156 and miR172 Regulates Developmental Timing in Arabidopsis

(2009) Gang Wu et al.   CELL

Hierarchical Rules for Argonaute Loading in Drosophila

(2009) Benjamin Czech et al.   MOLECULAR CELL

RNA polymerase V transcription guides ARGONAUTE4 to chromatin

(2009) Andrzej T Wierzbicki et al.   NATURE GENETICS

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins

(2009) Bingbing Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Arabidopsis thaliana double-stranded RNA binding protein DRB1 directs guide strand selection from microRNA duplexes

(2009) A. L. Eamens et al.   RNA

RNAi in Budding Yeast

(2009) I. A. Drinnenberg et al.   SCIENCE

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY

Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation

(2008) Taiowa A. Montgomery et al.   CELL

Noncoding Transcription by RNA Polymerase Pol IVb/Pol V Mediates Transcriptional Silencing of Overlapping and Adjacent Genes

(2008) Andrzej T. Wierzbicki et al.   CELL

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL

The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution

(2008) Katsutomo Okamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Mechanism Selecting the Guide Strand from Small RNA Duplexes is Different Among Argonaute Proteins

(2008) Atsushi Takeda et al.   PLANT AND CELL PHYSIOLOGY

PolIVb influences RNA-directed DNA methylation independently of its role in siRNA biogenesis

(2008) R. A. Mosher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deadenylation is a widespread effect of miRNA regulation

(2008) A. Eulalio et al.   RNA

An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

(2008) J. Brennecke et al.   SCIENCE

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE

Origins and evolution of eukaryotic RNA interference

(2008) S SHABALINA et al.   TRENDS IN ECOLOGY & EVOLUTION

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY