Binding and entry ofClostridium difficiletoxin B is mediated by multiple domains

Human neutrophils are activated by a peptide fragment ofClostridium difficiletoxin B presumably via formyl peptide receptor

(2015) Sebastian D. Goy et al.   CELLULAR MICROBIOLOGY

Identification of an epithelial cell receptor responsible forClostridium difficileTcdB-induced cytotoxicity

(2015) Michelle E. LaFrance et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B

(2014) Pengfei Yuan et al.   CELL RESEARCH

Pyknotic cell death induced byClostridium difficile TcdB: chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity

(2014) Katharina Wohlan et al.   CELLULAR MICROBIOLOGY

LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins

(2014) B. Schorch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of Severe Clostridium difficile Infection

(2013) Stephen R. Eaton et al.   CRITICAL CARE CLINICS

Cellular uptake of Clostridium difficile TcdA and truncated TcdA lacking the receptor binding domain

(2013) R. Gerhard et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

(2012) Nicole M. Chumbler et al.   PLoS Pathogens

Toward a structural understanding of Clostridium difficile toxins A and B

(2012) Rory N. Pruitt et al.   Frontiers in Cellular and Infection Microbiology

Cytotoxicity ofClostridium difficiletoxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol

(2012) Shan Li et al.   Pathogens and Disease

Binding of Clostridium difficile toxins to human milk oligosaccharides

(2011) Amr El-Hawiet et al.   GLYCOBIOLOGY

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B

(2011) Selda Genisyuerek et al.   MOLECULAR MICROBIOLOGY

The Repetitive Oligopeptide Sequences Modulate Cytopathic Potency but Are Not Crucial for Cellular Uptake of Clostridium difficile Toxin A

(2011) Alexandra Olling et al.   PLoS One

Clostridial Glucosylating Toxins Enter Cells via Clathrin-Mediated Endocytosis

(2010) Panagiotis Papatheodorou et al.   PLoS One

Structural organization of the functional domains of Clostridium difficile toxins A and B

(2010) R. N. Pruitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Functional properties of the carboxy-terminal host cell-binding domains of the two toxins, TcdA and TcdB, expressed by Clostridium difficile

(2008) T. Dingle et al.   GLYCOBIOLOGY

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY