Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

(2014) Yuexin Zhou et al.   NATURE

LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins

(2014) B. Schorch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular uptake of Clostridium difficile TcdA and truncated TcdA lacking the receptor binding domain

(2013) R. Gerhard et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Procalcitonin Levels Associate with Severity of Clostridium difficile Infection

(2013) Krishna Rao et al.   PLoS One

ULtiMATE System for Rapid Assembly of Customized TAL Effectors

(2013) Junjiao Yang et al.   PLoS One

Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex

(2013) M. A. Farrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clostridium difficile 027/BI/NAP1 Encodes a Hypertoxic and Antigenically Variable Form of TcdB

(2013) Jordi M. Lanis et al.   PLoS Pathogens

FH535 Inhibited Migration and Growth of Breast Cancer Cells

(2012) Joji Iida et al.   PLoS One

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

(2012) Nicole M. Chumbler et al.   PLoS Pathogens

Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models

(2011) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B

(2011) Selda Genisyuerek et al.   MOLECULAR MICROBIOLOGY

The Repetitive Oligopeptide Sequences Modulate Cytopathic Potency but Are Not Crucial for Cellular Uptake of Clostridium difficile Toxin A

(2011) Alexandra Olling et al.   PLoS One

Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen

(2010) Claudia Bluemel et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CSPG4 in Cancer: Multiple Roles

(2010) X. Wang et al.   CURRENT MOLECULAR MEDICINE

Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy

(2010) Lorna et al.   Frontiers in Bioscience-Landmark

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Clostridial Glucosylating Toxins Enter Cells via Clathrin-Mediated Endocytosis

(2010) Panagiotis Papatheodorou et al.   PLoS One

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

(2008) Guilin Yang et al.   BMC MICROBIOLOGY

gp96 Is a Human Colonocyte Plasma Membrane Binding Protein for Clostridium difficile Toxin A

(2008) X. Na et al.   INFECTION AND IMMUNITY

Interaction of Syntenin-1 and the NG2 Proteoglycan in Migratory Oligodendrocyte Precursor Cells

(2008) Nivedita Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY