Amphiregulin enhances cardiac fibrosis and aggravates cardiac dysfunction in mice with experimental myocardial infarction partly through activating EGFR-dependent pathway

A heart–brain–kidney network controls adaptation to cardiac stress through tissue macrophage activation

(2017) Katsuhito Fujiu et al.   NATURE MEDICINE

Classically Activated Macrophages Protect against Lipopolysaccharide-induced Acute Lung Injury by Expressing Amphiregulin in Mice

(2016) Younian Xu et al.   ANESTHESIOLOGY

Bone Marrow CD11c+Cell–Derived Amphiregulin Promotes Pulmonary Fibrosis

(2016) Lin Ding et al.   JOURNAL OF IMMUNOLOGY

Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis

(2016) Kathleen Meyer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Distinct Function of Regulatory T Cells in Tissue Protection

(2015) Nicholas Arpaia et al.   CELL

SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer

(2015) Andreas I Papadakis et al.   CELL RESEARCH

The war against heart failure: the Lancet lecture

(2015) Eugene Braunwald   LANCET

Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

(2015) Chad McKee et al.   Scientific Reports

Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction

(2014) Timo Heidt et al.   CIRCULATION RESEARCH

Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction

(2014) Pooja Shivshankar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiovascular remodelling in coronary artery disease and heart failure

(2014) Gerd Heusch et al.   LANCET

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Intermittent hypoxia induces the proliferation of rat vascular smooth muscle cell with the increases in epidermal growth factor family and erbB2 receptor

(2013) Yoji Kyotani et al.   EXPERIMENTAL CELL RESEARCH

Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

(2013) Bryan C. Fuchs et al.   HEPATOLOGY

Origin, development, and differentiation of cardiac fibroblasts

(2013) Jacquelyn D. Lajiness et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Serum-Glucocorticoid Regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Contributing to Angiotensin II–Induced Inflammation and Cardiac Fibrosis

(2012) Min Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The prostacyclin agonist iloprost aggravates fibrosis and enhances viral replication in enteroviral myocarditis by modulation of ERK signaling and increase of iNOS expression

(2012) Stefan Gruhle et al.   BASIC RESEARCH IN CARDIOLOGY

Activation of CD4 + T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice

(2012) Ulrich Hofmann et al.   CIRCULATION

Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

(2012) Yang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

(2012) Anirudh Prahallad et al.   NATURE

The multiple roles of amphiregulin in human cancer

(2011) Benoit Busser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

TGF-β 1 -Mediated Fibrosis and Ion Channel Remodeling Are Key Mechanisms in Producing the Sinus Node Dysfunction Associated With SCN5A Deficiency and Aging

(2011) Xiaojin Hao et al.   Circulation-Arrhythmia and Electrophysiology

S100B-RAGE dependent VEGF secretion by cardiac myocytes induces myofibroblast proliferation

(2011) James N. Tsoporis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

(2010) Jon-Jon Santiago et al.   DEVELOPMENTAL DYNAMICS

Silibinin attenuates cardiac hypertrophy and fibrosis through blocking EGFR-dependent signaling

(2010) Wen Ai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Macrophage depletion suppresses sympathetic hyperinnervation following myocardial infarction

(2009) Gwenaelle Wernli et al.   BASIC RESEARCH IN CARDIOLOGY

Targeted Deletion of Nuclear Factor κB p50 Enhances Cardiac Remodeling and Dysfunction Following Myocardial Infarction

(2009) Leo Timmers et al.   CIRCULATION RESEARCH

IGF-I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats

(2009) Luciano Sobrevals et al.   HEPATOLOGY

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop

(2008) Nicole E. Willmarth et al.   CELLULAR SIGNALLING

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis

(2008) Maria J. Perugorria et al.   HEPATOLOGY