HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer

Mitochondrial E3 Ubiquitin Protein Ligase 1 Mediates Cigarette Smoke–Induced Endothelial Cell Death and Dysfunction

(2016) Sun-Yong Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

(2016) Michaël Cerezo et al.   CANCER CELL

Non-thermal plasma inhibits human cervical cancer HeLa cells invasiveness by suppressing the MAPK pathway and decreasing matrix metalloproteinase-9 expression

(2016) Wei Li et al.   Scientific Reports

Anti-cancer Effect of Luminacin, a Marine Microbial Extract, in Head and Neck Squamous Cell Carcinoma Progression via Autophagic Cell Death

(2016) Yoo Seob Shin et al.   Cancer Research and Treatment

Iron stimulates plasma-activated medium-induced A549 cell injury

(2016) Tetsuo Adachi et al.   Scientific Reports

Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy

(2015) Jie Li et al.   Autophagy

TMEM175 Is an Organelle K + Channel Regulating Lysosomal Function

(2015) Chunlei Cang et al.   CELL

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial–nuclear network

(2015) Tetsuo Adachi et al.   FREE RADICAL BIOLOGY AND MEDICINE

ERK2 Mediates Metabolic Stress Response to Regulate Cell Fate

(2015) Sejeong Shin et al.   MOLECULAR CELL

Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy

(2015) Esperanza Arias et al.   MOLECULAR CELL

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer

(2015) Y-W Chang et al.   ONCOGENE

Non-thermal plasma induces AKT degradation through turn-on the MUL1 E3 ligase in head and neck cancer

(2015) Sun-Yong Kim et al.   Oncotarget

Non-thermal atmospheric pressure plasma induces apoptosis in oral cavity squamous cell carcinoma: Involvement of DNA-damage-triggering sub-G1 arrest via the ATM/p53 pathway

(2014) Jae Won Chang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Endoplasmic Reticulum Stress in Malignancy

(2014) Hanna J. Clarke et al.   CANCER CELL

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Non-Thermal Atmospheric Pressure Plasma Inhibits Thyroid Papillary Cancer Cell Invasion via Cytoskeletal Modulation, Altered MMP-2/-9/uPA Activity

(2014) Jae Won Chang et al.   PLoS One

Nonthermal plasma induces head and neck cancer cell death: the potential involvement of mitogen-activated protein kinase-dependent mitochondrial reactive oxygen species

(2014) S U Kang et al.   Cell Death & Disease

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

(2014) Clotilde Wiel et al.   Nature Communications

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

(2012) Sylvain Ladoire et al.   Autophagy

Akt is negatively regulated by the MULAN E3 ligase

(2012) Seunghee Bae et al.   CELL RESEARCH

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Ubiquitin receptors and protein quality control

(2012) Xuejun Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner

(2011) Hong Wa Yung et al.   PLoS One

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells

(2010) Chul-Ho Kim et al.   APPLIED PHYSICS LETTERS

Under the ROS: Thiol network is the principal suspect for autophagy commitment

(2010) Giuseppe Filomeni et al.   Autophagy

Induction of cell growth arrest by atmospheric non-thermal plasma in colorectal cancer cells

(2010) Chul-Ho Kim et al.   JOURNAL OF BIOTECHNOLOGY

Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells

(2010) Yidan Lin et al.   LUNG CANCER

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

The SUMO arena goes mitochondrial with MAPL

(2009) Luca Scorrano et al.   EMBO REPORTS

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

(2009) Emélie Braschi et al.   EMBO REPORTS

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Non-thermal plasma technologies: New tools for bio-decontamination

(2008) M. Moreau et al.   BIOTECHNOLOGY ADVANCES

GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth

(2008) Bicheng Zhang et al.   CELL RESEARCH

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One