Soluble TL1A is sufficient for activation of death receptor 3

Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease

(2015) B.-S. Kim et al.   BLOOD

Principles of antibody-mediated TNF receptor activation

(2015) H Wajant   CELL DEATH AND DIFFERENTIATION

The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator

(2015) Arianne C. Richard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Membrane Trafficking of Death Receptors: Implications on Signalling

(2013) Wulf Schneider-Brachert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fibroblast Growth Factor Inducible (Fn14)-specific Antibodies Concomitantly Display Signaling Pathway-specific Agonistic and Antagonistic Activity

(2013) Steffen Salzmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cloning, Expression, and Functional Characterization of TL1A-Ig

(2013) S. Q. Khan et al.   JOURNAL OF IMMUNOLOGY

Signaling Active CD95 Receptor Molecules Trigger Co-translocation of Inactive CD95 Molecules into Lipid Rafts

(2012) Isabell Lang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation

(2012) S Jin et al.   Mucosal Immunology

Cellular Inhibitors of Apoptosis Are Global Regulators of NF- B and MAPK Activation by Members of the TNF Family of Receptors

(2012) E. Varfolomeev et al.   Science Signaling

Tregs Expanded In Vivo by TNFRSF25 Agonists Promote Cardiac Allograft Survival

(2012) Dietlinde Wolf et al.   TRANSPLANTATION

Studies of Binding of Tumor Necrosis Factor (TNF)-like Weak Inducer of Apoptosis (TWEAK) to Fibroblast Growth Factor Inducible 14 (Fn14)

(2011) Andrea Fick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation

(2010) M Ehrenschwender et al.   CELL DEATH AND DIFFERENTIATION

Functional signaling of membrane-bound TL1A induces IFN-γ expression

(2010) Eva Biener-Ramanujan et al.   FEBS LETTERS

Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation

(2010) Taylor H. Schreiber et al.   JOURNAL OF CLINICAL INVESTIGATION

TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling

(2009) A Wicovsky et al.   CELL DEATH AND DIFFERENTIATION

Trimer Stabilization, Oligomerization, and Antibody-Mediated Cell Surface Immobilization Improve the Activity of Soluble Trimers of CD27L, CD40L, 41BBL, and Glucocorticoid-Induced TNF Receptor Ligand

(2009) A. Wyzgol et al.   JOURNAL OF IMMUNOLOGY

Activity of soluble OX40 ligand is enhanced by oligomerization and cell surface immobilization

(2008) Nicole Müller et al.   FEBS Journal

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

(2008) James E. Vince et al.   JOURNAL OF CELL BIOLOGY

TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease

(2008) Bhanu P. Pappu et al.   JOURNAL OF EXPERIMENTAL MEDICINE