Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions

Identification of Inhibitors of Biological Interactions Involving Intrinsically Disordered Proteins

(2015) Daniela Marasco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

G-quadruplex DNA recognition by nucleophosmin: New insights from protein dissection

(2014) Pasqualina Liana Scognamiglio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synergic Role of Nucleophosmin Three-helix Bundle and a Flanking Unstructured Tail in the Interaction with G-quadruplex DNA

(2014) Alessandro Arcovito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins

(2014) Mattia Poletto et al.   MOLECULAR BIOLOGY OF THE CELL

Structural polymorphism in the N-terminal oligomerization domain of NPM1

(2014) D. M. Mitrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion-like aggregation of mutant p53 in cancer

(2014) Jerson L. Silva et al.   TRENDS IN BIOCHEMICAL SCIENCES

The folding pathway of a functionally competent C-terminal domain of nucleophosmin: Protein stability and denatured state residual structure

(2013) Sara Chiarella et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA

(2013) Sara Chiarella et al.   NUCLEIC ACIDS RESEARCH

Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains

(2012) Daniela Marasco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling

(2012) M. Okuwaki et al.   NUCLEIC ACIDS RESEARCH

Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1

(2011) R. Balusu et al.   BLOOD

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

The induction of  -helical structure in partially unfolded HypF-N does not affect its aggregation propensity

(2011) B. Ahmad et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

(2010) B. Falini et al.   BLOOD

Mutant nucleophosmin deregulates cell death and myeloid differentiation through excessive caspase-6 and -8 inhibition

(2010) S. M. Leong et al.   BLOOD

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives

(2010) Brunangelo Falini et al.   CURRENT OPINION IN ONCOLOGY

Deciphering the folding transition state structure and denatured state properties of Nucleophosmin C-terminal domain

(2010) F. Scaloni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance

(2009) Flavio Scaloni et al.   FASEB JOURNAL

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

(2009) Sean A. Hudson et al.   FEBS Journal

NetCSSP: web application for predicting chameleon sequences and amyloid fibril formation

(2009) C. Kim et al.   NUCLEIC ACIDS RESEARCH

Structure – Function Relationships of Pre-Fibrillar Protein Assemblies in Alzheimers Disease and Related Disorders

(2008) F. Rahimi et al.   Current Alzheimer Research

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia

(2008) Charles G. Grummitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin and ARF

(2008) N Bolli et al.   LEUKEMIA

Transcription Regulation of the rRNA Gene by a Multifunctional Nucleolar Protein, B23/Nucleophosmin, through Its Histone Chaperone Activity

(2008) K. Murano et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

(2008) L. B. Maggi et al.   MOLECULAR AND CELLULAR BIOLOGY

Cell systems and the toxic mechanism(s) of α-synuclein

(2007) Mark R. Cookson et al.   EXPERIMENTAL NEUROLOGY