Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA

Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYCPromoter

(2012) Angelo Gallo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5'-UTR RNA G-quadruplexes: translation regulation and targeting

(2012) A. Bugaut et al.   NUCLEIC ACIDS RESEARCH

Acute myeloid leukemia with mutated nucleophosmin (NPM1): Any hope for a targeted therapy?

(2011) Brunangelo Falini et al.   BLOOD REVIEWS

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

Spectroscopic study on the binding of porphyrins to (G4T4G4)4 parallel G-quadruplex

(2010) Chunying Wei et al.   BIOPHYSICAL CHEMISTRY

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

(2010) B. Falini et al.   BLOOD

Nucleophosmin C-terminal Leukemia-associated Domain Interacts with G-rich Quadruplex Forming DNA

(2010) Luca Federici et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Deciphering the folding transition state structure and denatured state properties of Nucleophosmin C-terminal domain

(2010) F. Scaloni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

(2009) D. Drygin et al.   CANCER RESEARCH

The structures of quadruplex nucleic acids and their drug complexes

(2009) Stephen Neidle   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nucleolar targeting: the hub of the matter

(2009) Edward Emmott et al.   EMBO REPORTS

Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance

(2009) Flavio Scaloni et al.   FASEB JOURNAL

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications

(2009) B Falini et al.   LEUKEMIA

Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells

(2008) Mohammed Abdullahel Amin et al.   BIOCHEMICAL JOURNAL

Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes

(2008) Julian Leon Huppert   CHEMICAL SOCIETY REVIEWS

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia

(2008) Charles G. Grummitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ

(2008) Paola Bonetti et al.   JOURNAL OF CELL BIOLOGY

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

(2008) L. B. Maggi et al.   MOLECULAR AND CELLULAR BIOLOGY