Focal adhesion kinase phosphorylates the phosphatase and tensin homolog deleted on chromosome 10 under the control of p110δ phosphoinositide-3 kinase

Biophysical methods for the characterization of PTEN/lipid bilayer interactions

(2015) Rakesh K. Harishchandra et al.   METHODS

Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity

(2014) Victoria L. B. Nelson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

(2013) Lazaros C. Foukas et al.   EMBO Molecular Medicine

Regulation of Focal Adhesion Kinase Activation, Breast Cancer Cell Motility, and Amoeboid Invasion by the RhoA Guanine Nucleotide Exchange Factor Net1

(2013) H. S. Carr et al.   MOLECULAR AND CELLULAR BIOLOGY

FAK-heterozygous mice display enhanced tumour angiogenesis

(2013) Vassiliki Kostourou et al.   Nature Communications

Macrophages and chemokines as mediators of angiogenesis

(2013) Jennifer L. Owen et al.   Frontiers in Physiology

High levels of p110δ PI3K expression in solid tumor cells suppress PTEN activity, generating cellular sensitivity to p110δ inhibitors through PTEN activation

(2012) Niki Tzenaki et al.   FASEB JOURNAL

PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance

(2012) Amit Gupta et al.   MOLECULAR BIOLOGY OF THE CELL

Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells

(2011) Lakshmi S. Chaturvedi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis

(2011) Shouye Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolismin vivo

(2011) Greg C. Smith et al.   BIOCHEMICAL JOURNAL

Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells

(2011) Oumou Goundiam et al.   CELL BIOLOGY INTERNATIONAL

Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation

(2011) Carmine Giorgio et al.   PLoS One

Endothelial FAK is required for tumour angiogenesis

(2010) Bernardo Tavora et al.   EMBO Molecular Medicine

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

Both p110α and p110β Isoforms of Phosphatidylinositol 3-OH-Kinase are Required for Insulin Signalling in the Hypothalamus

(2010) A. Tups et al.   JOURNAL OF NEUROENDOCRINOLOGY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase

(2010) R. B. Chagpar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

Rak Functions as a Tumor Suppressor by Regulating PTEN Protein Stability and Function

(2009) Eun-Kyoung Yim et al.   CANCER CELL

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

(2009) Hind Al-Qassab et al.   Cell Metabolism

p85 Associates with Unphosphorylated PTEN and the PTEN-Associated Complex

(2009) R. Rabinovsky et al.   MOLECULAR AND CELLULAR BIOLOGY

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Ser/Thr/Tyr Protein Phosphorylation in the Archaeon Halobacterium salinarum—A Representative of the Third Domain of Life

(2009) Michalis Aivaliotis et al.   PLoS One

Activation of the PI3K Pathway in Cancer Through Inhibition of PTEN by Exchange Factor P-REX2a

(2009) B. Fine et al.   SCIENCE

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Biphasic function of focal adhesion kinase in endothelial tube formation induced by fibril-forming collagens

(2008) Junko Nakamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages

(2008) E. A. Papakonstanti et al.   JOURNAL OF CELL SCIENCE

In vivoinhibition of focal adhesion kinase causes insulin resistance

(2008) Bharti Bisht et al.   JOURNAL OF PHYSIOLOGY-LONDON