Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms

Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease

(2014) Puneet Talwar et al.   BMC GENOMICS

Presenilin-1/γ-Secretase Controls Glutamate Release, Tyrosine Phosphorylation, and Surface Expression ofN-Methyl-d-aspartate Receptor (NMDAR) Subunit GluN2B

(2013) Zhao Xuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

(2013) Jia Shen et al.   NATURE

Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors

(2012) Gael Barthet et al.   NEUROBIOLOGY OF AGING

Epidermal growth factor receptor is a preferred target for treating Amyloid- -induced memory loss

(2012) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular mechanisms of γ-secretase substrate selection, processing and toxicity

(2012) Gael Barthet et al.   PROGRESS IN NEUROBIOLOGY

Central Role of the EGF Receptor in Neurometabolic Aging

(2012) Sana Siddiqui et al.   International Journal of Endocrinology

Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates

(2011) Gael Barthet et al.   FASEB JOURNAL

Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

(2011) A. Gadadhar et al.   JOURNAL OF NEUROSCIENCE

Feedback regulation of EGFR signalling: decision making by early and delayed loops

(2011) Roi Avraham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling

(2011) Jindong Xu et al.   NEUROBIOLOGY OF AGING

Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer

(2011) Carmen Berasain et al.   Cancers

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

The Effect of Epidermal Growth Factor in the Injured Brain after Trauma in Rats

(2010) Dong Sun et al.   JOURNAL OF NEUROTRAUMA

Molecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimer's disease as based on APOE genotype

(2010) C Conejero-Goldberg et al.   MOLECULAR PSYCHIATRY

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

(2010) V Rocher-Ros et al.   ONCOGENE

Indirect Regulation of Presenilins in CREB-mediated Transcription

(2009) Hirotaka Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wild-Type But Not FAD Mutant Presenilin-1 Prevents Neuronal Degeneration by Promoting Phosphatidylinositol 3-Kinase Neuroprotective Signaling

(2008) L. Baki et al.   JOURNAL OF NEUROSCIENCE