The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases

A Synergistic Dysfunction of Mitochondrial Fission/Fusion Dynamics and Mitophagy in Alzheimer's Disease

(2017) Renato X. Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Perspectives on cellular senescence and short term dietary restriction in adults

(2016) James L. Kirkland   Aging-US

NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease

(2015) V. Corsetti et al.   HUMAN MOLECULAR GENETICS

Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains

(2015) Xuan Ye et al.   HUMAN MOLECULAR GENETICS

Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease–like pathology

(2015) Wei Zhang et al.   NEUROBIOLOGY OF AGING

SIRT3 Attenuates MPTP-Induced Nigrostriatal Degeneration Via Enhancing Mitochondrial Antioxidant Capacity

(2015) Lei Liu et al.   NEUROCHEMICAL RESEARCH

Glutathione transferases and neurodegenerative diseases

(2015) Anna Paola Mazzetti et al.   NEUROCHEMISTRY INTERNATIONAL

PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein

(2015) Carine Ciron et al.   Acta Neuropathologica Communications

The mitochondrial genome in aging and senescence

(2014) Andrea Lauri et al.   AGEING RESEARCH REVIEWS

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway

(2014) Gurdeep Marwarha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria as signaling organelles

(2014) Navdeep S Chandel   BMC BIOLOGY

Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation

(2014) Jaswinder Sharma et al.   BMC NEUROSCIENCE

Inhibition of Akt Phosphorylation Diminishes Mitochondrial Biogenesis Regulators, Tricarboxylic Acid Cycle Activity and Exacerbates Recognition Memory Deficit in Rat Model of Alzheimer’s Disease

(2014) Fatemeh Shaerzadeh et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease

(2014) Magali Dumont et al.   FASEB JOURNAL

Quantitative proteomic analysis reveals mitochondrial protein changes in MPP+-induced neuronal cells

(2014) Jee Won Choi et al.   Molecular BioSystems

Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity

(2014) Pengcheng Han et al.   NEUROBIOLOGY OF AGING

Mitochondria and the central nervous system: searching for a pathophysiological basis of psychiatric disorders

(2014) Emilio L. Streck et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

(2014) Xuan Ou et al.   STEM CELLS

Parkin and PINK1: much more than mitophagy

(2014) Leslie A. Scarffe et al.   TRENDS IN NEUROSCIENCES

Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin

(2014) R A Charan et al.   Cell Death & Disease

Mitochondrial Dysfunctions in Neurodegenerative Diseases: Relevance to Alzheimer’s Disease

(2014) Jana Hroudová et al.   Biomed Research International

Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease

(2013) Petar Podlesniy et al.   ANNALS OF NEUROLOGY

Mitochondrial respiration as a target for neuroprotection and cognitive enhancement

(2013) F. Gonzalez-Lima et al.   BIOCHEMICAL PHARMACOLOGY

Mitochondrial genome changes and neurodegenerative diseases

(2013) Milena Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

(2013) Russell H. Swerdlow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Clinical and genetic features of Huntington disease in Sri Lanka

(2013) Dulika S Sumathipala et al.   BMC Neurology

Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease

(2013) Sonia C. Correia et al.   Current Alzheimer Research

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

(2013) Maria Damiano et al.   HUMAN MOLECULAR GENETICS

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

(2013) D. F. Silva et al.   HUMAN MOLECULAR GENETICS

Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity

(2013) Serena Dato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Principles of the mitochondrial fusion and fission cycle in neurons

(2013) M. Cagalinec et al.   JOURNAL OF CELL SCIENCE

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

(2013) Jaime M. Ross et al.   NATURE

Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

(2013) Robert P Mason et al.   NATURE GENETICS

Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons

(2013) Lan Guo et al.   PLoS One

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

(2013) R. Tarawneh et al.   Cold Spring Harbor Perspectives in Medicine

Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a “chi”

(2013) Carolin Cornelius et al.   Immunity & Ageing

Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes

(2013) Carolin Cornelius et al.   Immunity & Ageing

Synaptic Activity and Bioenergy Homeostasis: Implications in Brain Trauma and Neurodegenerative Diseases

(2013) Natasha Khatri et al.   Frontiers in Neurology

Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration

(2013) Joseph McInnes   Translational Neurodegeneration

Cellular and molecular mechanisms of mitochondrial function

(2012) Laura D. Osellame et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH

(2012) L Pellegrini et al.   CELL DEATH AND DIFFERENTIATION

Metabolic Alterations Induced by Sucrose Intake and Alzheimer’s Disease Promote Similar Brain Mitochondrial Abnormalities

(2012) Cristina Carvalho et al.   DIABETES

Shaping the role of mitochondria in the pathogenesis of Huntington's disease

(2012) Veronica Costa et al.   EMBO JOURNAL

Mitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer’s disease

(2012) S. Wang et al.   EUROPEAN JOURNAL OF NEUROLOGY

Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells

(2012) Márcio Ribeiro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial DNA damage Is associated with reduced mitochondrial bioenergetics in Huntington's disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases?

(2012) Marta Di Carlo et al.   FREE RADICAL RESEARCH

Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: Implication in autosomal recessive juvenile Parkinsonism

(2012) Leonardo Bonilla-Ramirez et al.   GENE

Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice

(2012) Magali Dumont et al.   HUMAN MOLECULAR GENETICS

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

(2012) Daniela M. Arduíno et al.   HUMAN MOLECULAR GENETICS

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

(2012) X. Wang et al.   HUMAN MOLECULAR GENETICS

Neuroglobin, a Novel Target for Endogenous Neuroprotection against Stroke and Neurodegenerative Disorders

(2012) Zhanyang Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

trans-(−)-ϵ-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease

(2012) Jinrong Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R6/2 Huntington's Disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures

(2012) E. Cepeda-Prado et al.   JOURNAL OF NEUROSCIENCE

SIRT1 Protects against  -Synuclein Aggregation by Activating Molecular Chaperones

(2012) G. Donmez et al.   JOURNAL OF NEUROSCIENCE

Protein–RNA interactions: new genomic technologies and perspectives

(2012) Julian König et al.   NATURE REVIEWS GENETICS

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α

(2012) Wenjun Song et al.   NEUROBIOLOGY OF DISEASE

Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease

(2012) Eugenia Trushina et al.   PLoS One

CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease

(2012) Heather J. M. Weir et al.   PLoS One

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

The neurobiology of sirtuins and their role in neurodegeneration

(2012) Gizem Donmez   TRENDS IN PHARMACOLOGICAL SCIENCES

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Extending life span by increasing oxidative stress

(2011) Michael Ristow et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

(2011) Ashu Johri et al.   HUMAN MOLECULAR GENETICS

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

(2011) M. J. Calkins et al.   HUMAN MOLECULAR GENETICS

Neuroglobin is up-regulated in the cerebellum of pups exposed to maternal epileptic seizures

(2011) Daiana Correia Lima et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Sirtuins at a glance

(2011) T. Nakagawa et al.   JOURNAL OF CELL SCIENCE

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

β-Apptists and Tauists, it is time for a sermon from the book of biogenesis

(2011) Russell H. Swerdlow   JOURNAL OF NEUROCHEMISTRY

Evaluation of respiratory chain activity in lymphocytes of patients with Alzheimer disease

(2011) Pollyana Feldhaus et al.   METABOLIC BRAIN DISEASE

Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture

(2011) Sun Hee Kim et al.   PLoS One

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Autophagy in health and disease. 5. Mitophagy as a way of life

(2010) Roberta A. Gottlieb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

PGC-1α is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle

(2010) Lotte Leick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

(2010) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Principles of control over formation of structures responsible for respiratory functions of mitochondria

(2010) V. N. Luzikov   BIOCHEMISTRY-MOSCOW

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

(2010) Frits Kamp et al.   EMBO JOURNAL

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

(2010) Veronica Costa et al.   EMBO Molecular Medicine

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

(2010) Michael Ristow et al.   EXPERIMENTAL GERONTOLOGY

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

(2010) Daniel J. Ho et al.   EXPERIMENTAL NEUROLOGY

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

(2010) Valérie Vingtdeux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Resveratrol as a Therapeutic Agent for Neurodegenerative Diseases

(2010) Albert Y. Sun et al.   MOLECULAR NEUROBIOLOGY

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

(2010) Marta Martinez-Vicente et al.   NATURE NEUROSCIENCE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease

(2010) B. Zheng et al.   Science Translational Medicine

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications

(2010) Rebecca Banerjee et al.   TRENDS IN NEUROSCIENCES

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

(2009) Akihiko Nunomura et al.   ACTA NEUROPATHOLOGICA

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection

(2009) Kenichi Kakefuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking†

(2009) Andreas Weihofen et al.   BIOCHEMISTRY

Abnormal mitochondrial dynamics and neurodegenerative diseases

(2009) Bo Su et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial structural and functional dynamics in Huntington's disease

(2009) P. Hemachandra Reddy et al.   BRAIN RESEARCH REVIEWS

Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway

(2009) G Liot et al.   CELL DEATH AND DIFFERENTIATION

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

(2009) Paula M. Keeney et al.   HUMAN GENE THERAPY

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Brain mitochondrial dysfunction and oxidative damage in Parkinson’s disease

(2009) Ana Navarro et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

(2009) A. Kathrin Lutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?

(2009) Frank Gillardon   JOURNAL OF NEUROCHEMISTRY

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

(2009) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression

(2009) Shilpa Iyer et al.   MITOCHONDRION

The gene coding for PGC-1α modifies age at onset in Huntington's Disease

(2009) Patrick Weydt et al.   Molecular Neurodegeneration

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

(2009) Andrew F. MacAskill et al.   NEURON

α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity

(2009) Guangwei Liu et al.   NEUROSCIENCE LETTERS

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

Control of mitochondrial transport and localization in neurons

(2009) Andrew F. MacAskill et al.   TRENDS IN CELL BIOLOGY

Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients

(2008) Xinglong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Therapeutic role of sirtuins in neurodegenerative disease

(2008) Tiago Fleming Outeiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Age related mitochondrial degenerative disorders in humans

(2008) Amy K. Reeve et al.   Biotechnology Journal

Reactive species: A cell damaging rout assisting to chemical carcinogens

(2008) Mario E. Goetz et al.   CANCER LETTERS

Activation of Mitochondrial Biogenesis by Hormesis

(2008) Motoaki Sano et al.   CIRCULATION RESEARCH

Targeting the mitochondria to augment myocardial protection

(2008) D SCHWARTZ et al.   CURRENT OPINION IN PHARMACOLOGY

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

(2008) Rosa Resende et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

(2008) K. N. Green et al.   JOURNAL OF NEUROSCIENCE

N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking

(2008) A. L. Orr et al.   JOURNAL OF NEUROSCIENCE

Metformin Protects the Brain Against the Oxidative Imbalance Promoted by Type 2 Diabetes

(2008) Sonia Correia et al.   Medicinal Chemistry

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

(2008) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

(2008) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutant huntingtin and mitochondrial dysfunction

(2008) Ella Bossy-Wetzel et al.   TRENDS IN NEUROSCIENCES

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology

Parkinson's disease and aging: Same or different process?

(2007) Christopher H. Hawkes   MOVEMENT DISORDERS

Nonmotor symptoms of Parkinson's disease: Prevalence and awareness of patients and families

(2007) Sang-Myung Cheon et al.   PARKINSONISM & RELATED DISORDERS