Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

(2013) Marian Beekman et al.   AGING CELL

Review of Selenium and Prostate Cancer Prevention

(2013) Lei Yang et al.   Asian Pacific Journal of Cancer Prevention

Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans

(2013) Alberto Montesanto et al.   BIOGERONTOLOGY

The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy

(2013) Fabio Concetti et al.   EXPERIMENTAL GERONTOLOGY

Vascular ageing: The role of oxidative stress

(2013) Annibale Alessandro Puca et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Okinawan Diet: Health Implications of a Low-Calorie, Nutrient-Dense, Antioxidant-Rich Dietary Pattern Low in Glycemic Load

(2013) D. Craig Willcox et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

(2013) Elsa Vera et al.   PLoS One

Dietary resveratrol prevents Alzheimer’s markers and increases life span in SAMP8

(2012) David Porquet et al.   AGE

MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case–control study using a multilocus genotyping

(2012) Fausta Di Cianni et al.   AGE

Evidence from case–control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity

(2012) Mette Soerensen et al.   AGE

Acute effects of resistance exercise and intermittent intense aerobic exercise on blood cell count and oxidative stress in trained middle-aged women

(2012) A.M. Cardoso et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Females Live Longer than Males: Role of Oxidative Stress

(2012) Jose Vina et al.   CURRENT PHARMACEUTICAL DESIGN

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies

(2012) Mette Soerensen et al.   EXPERIMENTAL GERONTOLOGY

Redox regulation of mitochondrial biogenesis

(2012) Claude A. Piantadosi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Actions of “antioxidants” in the protection against atherosclerosis

(2012) Maria E. Lönn et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT3 gene expression: A link between inherited mitochondrial DNA variants and oxidative stress

(2012) Patrizia D'Aquila et al.   GENE

Relationships between single nucleotide polymorphisms of antioxidant enzymes and disease

(2012) Amanda Crawford et al.   GENE

Mitochondria and cell signalling

(2012) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

TP53*P72 Allele Influences Negatively Female Life Expectancy in a Population of Central Italy: Cross-Sectional Study and Genetic-Demographic Approach Analysis

(2012) F. Di Pietro et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

(2012) I-Min Lee et al.   LANCET

UCP3 polymorphisms, hand grip performance and survival at old age: Association analysis in two Danish middle aged and elderly cohorts

(2012) Serena Dato et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Centenarians and diet: what they eat in the Western part of Sicily

(2012) Sonya Vasto et al.   Immunity & Ageing

Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes

(2011) Liana Spazzafumo et al.   AGE

Dietary restriction in rats and mice: A meta-analysis and review of the evidence for genotype-dependent effects on lifespan

(2011) William R. Swindell   AGEING RESEARCH REVIEWS

Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis

(2011) Mette Soerensen et al.   AGING CELL

Nucleus-encoded regulators of mitochondrial function: Integration of respiratory chain expression, nutrient sensing and metabolic stress

(2011) Richard C. Scarpulla   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

(2011) Vittorio Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A common polymorphism in the UCP3 promoter influences hand grip strength in elderly people

(2011) Paolina Crocco et al.   BIOGERONTOLOGY

Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity

(2011) Sangkyu Kim et al.   BIOGERONTOLOGY

Nitric Oxide-Derived Oxidants with a Focus on Peroxynitrite: Molecular Targets,Cellular Responses and Therapeutic Implications

(2011) P. Calcerrada et al.   CURRENT PHARMACEUTICAL DESIGN

Association of mtDNA haplogroup F with healthy longevity in the female Chuang population, China

(2011) Jie Feng et al.   EXPERIMENTAL GERONTOLOGY

Two variants located in the upstream enhancer region of human UCP1 gene affect gene expression and are correlated with human longevity

(2011) Giuseppina Rose et al.   EXPERIMENTAL GERONTOLOGY

Lifestyle Factors of People with Exceptional Longevity

(2011) Swapnil N. Rajpathak et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity

(2011) Giuseppina Rose et al.   PLoS One

No or only population-specific effect of PON1 on human longevity: A comprehensive meta-analysis

(2010) Amke Caliebe et al.   AGEING RESEARCH REVIEWS

Mitochondrial–nuclear epistasis: Implications for human aging and longevity

(2010) Gregory J. Tranah   AGEING RESEARCH REVIEWS

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

(2010) Mette Soerensen et al.   AGING CELL

A pathway that links reproductive status to lifespan in Caenorhabditis elegans

(2010) Cynthia Kenyon   Annals of the New York Academy of Sciences

Mediterranean diet and red wine protect against oxidative damage in young volunteers

(2010) Inés Urquiaga et al.   ATHEROSCLEROSIS

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

(2010) Michael Ristow et al.   EXPERIMENTAL GERONTOLOGY

Progeria syndromes and ageing: what is the connection?

(2010) Christopher R. Burtner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors

(2010) Marina Shargorodsky et al.   Nutrition & Metabolism

Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease

(2010) Aurelia Santoro et al.   PLoS One

Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study

(2010) Giuseppina Rose et al.   PLoS One

Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster

(2010) Kyu-Sun Lee et al.   REJUVENATION RESEARCH

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

(2009) Ludmila Pawlikowska et al.   AGING CELL

Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

(2009) Sang-Kyu Park et al.   AGING CELL

Effects of vitamins C and E and β-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trial

(2009) Yiqing Song et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Wine and oxidative stress: Up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humans

(2009) María Isabel Covas et al.   ATHEROSCLEROSIS

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Vitamin E Use Is Associated with Improved Survival in an Alzheimer’s Disease Cohort

(2009) Valory N. Pavlik et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Human longevity and 11p15.5: a study in 1321 centenarians

(2009) Francesco Lescai et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations

(2009) Yang Li et al.   HUMAN MOLECULAR GENETICS

Human genetic variations: Beacons on the pathways to successful ageing

(2009) Christie Cluett et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old

(2009) Mette Soerensen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Association of Mitochondrial DNA Haplogroups with Exceptional Longevity in a Chinese Population

(2009) Xiao-yun Cai et al.   PLoS One

Caloric restriction improves memory in elderly humans

(2009) A. V. Witte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

(2009) G. Atzmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study

(2009) Chiara Viviani Anselmi et al.   REJUVENATION RESEARCH

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Design of aging intervention studies: the NIA interventions testing program

(2008) N. L. Nadon et al.   AGE

Genes encoding longevity: from model organisms to humans

(2008) Maris Kuningas et al.   AGING CELL

Lipid peroxidation and decomposition — Conflicting roles in plaque vulnerability and stability

(2008) Sampath Parthasarathy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines

(2008) D. Bellizzi et al.   CELL STRESS & CHAPERONES

Should Supplemental Antioxidant Administration Be Avoided During Chemotherapy and Radiation Therapy?

(2008) B. D. Lawenda et al.   JNCI-Journal of the National Cancer Institute

Mitochondrial DNA Haplogroup D4a Is a Marker for Extreme Longevity in Japan

(2008) Erhan Bilal et al.   PLoS One

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA